Dexbrompheniramine + Pseudoephedrine

Find more information about this combination medication at the webpages for Dexbrompheniramine and Pseudoephedrine

Perennial Allergic Rhinitis, Asthma ... show more

Advisory

  • This medicine contains a combination of 2 drugs Dexbrompheniramine and Pseudoephedrine.
  • Dexbrompheniramine and Pseudoephedrine are both used to treat the same disease or symptom but work in different ways in the body.
  • Most doctors will advise making sure that each individual medicine is safe and effective before using a combination form.
  • The combination of Dexbrompheniramine and Pseudoephedrine is classified as a controlled substance. Due to its potential for abuse and addiction, the government restricts its prescription and usage.

Drug Status

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Government Approvals

None

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WHO Essential Medicine

NO

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Known Teratogen

NO

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Pharmaceutical Class

Alpha-Adrenergic Agonist

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Controlled Drug Substance

YES

Summary

  • Dexbrompheniramine and Pseudoephedrine are used to relieve symptoms of allergies and colds. These symptoms include nasal congestion, which is a stuffy nose, runny nose, sneezing, and itchy or watery eyes. Pseudoephedrine specifically targets nasal and sinus congestion, while Dexbrompheniramine addresses allergic reactions by blocking histamine, which is a substance in the body that causes allergy symptoms. Together, they provide a comprehensive treatment for both nasal and other allergy-related symptoms.

  • Pseudoephedrine works by narrowing blood vessels in the nasal passages, which reduces swelling and congestion. Dexbrompheniramine is an antihistamine, which means it blocks the action of histamine, a chemical in the body that causes allergic symptoms like sneezing and itching. Together, they provide comprehensive relief by addressing both nasal congestion and other allergy symptoms, making them effective for managing allergy and cold symptoms.

  • For adults, the usual dose of Pseudoephedrine is 60 mg every 4 to 6 hours, not exceeding 240 mg in 24 hours. Dexbrompheniramine is typically taken at a dose of 2 mg every 4 to 6 hours, with a maximum of 12 mg per day. Both medications can be taken with or without food, but taking them with food may help reduce stomach upset. It's important to follow the dosing instructions on the package or provided by a healthcare provider.

  • Common side effects of Dexbrompheniramine and Pseudoephedrine include restlessness, nausea, vomiting, weakness, and headache. Dexbrompheniramine may cause drowsiness, while Pseudoephedrine can lead to nervousness and difficulty sleeping. Serious side effects, though less common, include dizziness, fast or irregular heartbeat, and difficulty breathing. If any severe side effects occur, it is important to seek medical attention immediately.

  • Avoid using Dexbrompheniramine and Pseudoephedrine if you have taken MAOIs, which are a type of antidepressant, in the past two weeks, as this can cause dangerous interactions. People with heart disease, high blood pressure, thyroid disease, diabetes, or glaucoma should consult a doctor before use. Dexbrompheniramine can cause drowsiness, so caution is advised when driving or operating machinery. Pregnant or breastfeeding women should consult a healthcare provider before use.

Indications and Purpose

How does combination of Dexbrompheniramine and Pseudoephedrine work?

Dexbrompheniramine and Pseudoephedrine work together to alleviate symptoms of allergies and colds. Pseudoephedrine acts as a nasal decongestant by narrowing the blood vessels in the nasal passages, which reduces swelling and congestion. Dexbrompheniramine, an antihistamine, blocks the action of histamine, a chemical in the body that causes allergic symptoms like sneezing and itching. Together, they provide comprehensive relief by addressing both nasal congestion and other allergy symptoms.

How effective is combination of Dexbrompheniramine and Pseudoephedrine?

The effectiveness of Dexbrompheniramine and Pseudoephedrine is supported by their long-standing use in treating allergy and cold symptoms. Pseudoephedrine is well-documented for its ability to relieve nasal congestion by constricting blood vessels in the nasal passages. Dexbrompheniramine is effective in reducing allergic symptoms by blocking histamine receptors. Clinical studies and user experiences have shown that when combined, these medications provide comprehensive relief from both nasal congestion and other allergy symptoms, making them a popular choice for managing these conditions.

Directions for Use

What is the usual dose of combination of Dexbrompheniramine and Pseudoephedrine?

For adults, the usual daily dose of Pseudoephedrine is 60 mg every 4 to 6 hours, not exceeding 240 mg in 24 hours. Dexbrompheniramine is typically taken at a dose of 2 mg every 4 to 6 hours, with a maximum of 12 mg per day. Both medications should be taken as directed on the package or by a healthcare provider. It's important to follow dosing instructions carefully to avoid potential side effects or overdose. Both medications are used to relieve symptoms of allergies and colds, but they work in different ways: Pseudoephedrine as a decongestant and Dexbrompheniramine as an antihistamine.

How does one take combination of Dexbrompheniramine and Pseudoephedrine?

Dexbrompheniramine and Pseudoephedrine can be taken with or without food, but taking them with food may help reduce stomach upset. It is important to follow the dosing instructions on the package or provided by a healthcare provider. Avoid consuming large amounts of caffeine, as it can increase the side effects of Pseudoephedrine. Additionally, alcohol should be avoided as it can enhance the drowsiness effect of Dexbrompheniramine. Always use the measuring device provided with liquid forms to ensure accurate dosing.

For how long is combination of Dexbrompheniramine and Pseudoephedrine taken?

Dexbrompheniramine and Pseudoephedrine are typically used for short-term relief of allergy and cold symptoms. The duration of use should not exceed 7 days unless directed by a healthcare provider. This is because prolonged use can lead to side effects or mask underlying conditions that require medical attention. Both medications are intended to provide temporary relief from symptoms, and if symptoms persist beyond a week, it is advisable to consult a doctor.

How long does it take for combination of Dexbrompheniramine and Pseudoephedrine to work?

Dexbrompheniramine and Pseudoephedrine are often combined to relieve symptoms of allergies and nasal congestion. Pseudoephedrine, a nasal decongestant, typically starts working within 30 minutes, providing relief from nasal and sinus congestion. Dexbrompheniramine, an antihistamine, may take a bit longer to show effects, usually within 1 to 2 hours, as it works to alleviate symptoms like runny nose, sneezing, and itchy eyes. Together, these medications provide a comprehensive approach to managing allergy and cold symptoms, with Pseudoephedrine offering quick relief from congestion and Dexbrompheniramine addressing other allergy symptoms.

Warnings and Precautions

Are there harms and risks from taking combination of Dexbrompheniramine and Pseudoephedrine?

Common side effects of Dexbrompheniramine and Pseudoephedrine include restlessness, nausea, vomiting, weakness, and headache. Dexbrompheniramine may cause drowsiness, while Pseudoephedrine can lead to nervousness and difficulty sleeping. Serious side effects, though less common, include dizziness, fast or irregular heartbeat, and difficulty breathing. If any severe side effects occur, it is important to seek medical attention immediately. Both medications can cause side effects related to their action on the nervous system and should be used with caution.

Can I take combination of Dexbrompheniramine and Pseudoephedrine with other prescription drugs?

Dexbrompheniramine and Pseudoephedrine can interact with several prescription medications. Notably, they should not be used with monoamine oxidase inhibitors (MAOIs), which are used to treat depression and other conditions, as this can lead to dangerous increases in blood pressure. Additionally, combining these medications with other sedatives or tranquilizers can enhance drowsiness. It's important to inform your healthcare provider of all medications you are taking to avoid potential interactions and side effects.

Can I take combination of Dexbrompheniramine and Pseudoephedrine if I am pregnant?

The safety of Dexbrompheniramine and Pseudoephedrine during pregnancy is not fully established, and they should be used only if clearly needed and prescribed by a healthcare provider. Pseudoephedrine is generally avoided during the first trimester due to potential risks to the fetus, while Dexbrompheniramine's effects are less well-documented. Pregnant women should consult their healthcare provider to discuss the potential risks and benefits before using these medications. Alternative treatments may be considered based on the individual's health needs and pregnancy stage.

Can I take combination of Dexbrompheniramine and Pseudoephedrine while breastfeeding?

The safety of Dexbrompheniramine and Pseudoephedrine during lactation and breastfeeding is not fully established. Pseudoephedrine is known to pass into breast milk and may reduce milk production, while Dexbrompheniramine may also be excreted in breast milk and could potentially affect a nursing infant. Therefore, it is important for breastfeeding mothers to consult with a healthcare provider before using these medications to weigh the potential benefits and risks. Alternative treatments may be recommended depending on the specific circumstances.

Who should avoid taking combination of Dexbrompheniramine and Pseudoephedrine?

Important warnings for Dexbrompheniramine and Pseudoephedrine include avoiding use if you have taken MAOIs in the past two weeks, as this can cause dangerous interactions. People with heart disease, high blood pressure, thyroid disease, diabetes, or glaucoma should consult a doctor before use. Dexbrompheniramine can cause drowsiness, so caution is advised when driving or operating machinery. Both medications should be used with caution in children and should not be given to children under certain ages without medical advice. Pregnant or breastfeeding women should consult a healthcare provider before use.