Pseudoephedrine
Drug Status
Government Approvals
US(FDA), UK(BNF)
WHO Essential Medicine
NO
Known Teratogen
NO
Pharmaceutical Class
Alpha-Adrenergic Agonist
Controlled Drug Substance
No

Pseudoephedrine
Summary
Pseudoephedrine is used to provide relief from nasal and sinus congestion caused by colds, allergies, and hay fever.
Pseudoephedrine works by causing the blood vessels in your nasal passages to narrow. This reduces swelling and congestion, helping to relieve symptoms.
For adults and children over 12 years, the usual dose is 60 mg every 4 to 6 hours, not exceeding 240 mg in 24 hours. For children aged 6 to 11 years, the dose is 30 mg every 4 to 6 hours, not exceeding 120 mg in 24 hours. It is not recommended for children under 6 years of age.
Common side effects include restlessness, difficulty sleeping, nausea, vomiting, and headache. More serious side effects can include nervousness, dizziness, and irregular heartbeat.
Do not use Pseudoephedrine if you are taking or have recently stopped taking an MAOI. Consult a doctor if you have heart disease, high blood pressure, thyroid disease, diabetes, or trouble urinating due to an enlarged prostate. Pregnant or breastfeeding women should seek medical advice before use.
Indications and Purpose
How does Pseudoephedrine work?
Pseudoephedrine works by narrowing blood vessels in the nasal passages, reducing swelling and congestion. Think of it like turning down the flow of water in a hose to reduce pressure. This action helps clear nasal congestion, making it easier to breathe. Pseudoephedrine is effective for relieving symptoms of colds, allergies, and sinus infections.
Is Pseudoephedrine effective?
Pseudoephedrine is effective for relieving nasal congestion due to colds, allergies, or sinus infections. It works by narrowing blood vessels in the nasal passages, reducing swelling and congestion. Clinical studies support its effectiveness for these conditions. Always use pseudoephedrine as directed by your doctor for the best results.
What is Pseudoephedrine?
Pseudoephedrine is a decongestant used to relieve nasal congestion from colds, allergies, or sinus infections. It works by narrowing blood vessels in the nasal passages, reducing swelling and congestion. Pseudoephedrine is often used in combination with other medications to treat symptoms of colds and allergies. Always use it as directed by your doctor.
Directions for Use
For how long do I take Pseudoephedrine?
Pseudoephedrine is usually used for short-term relief of nasal congestion. Take it as directed by your doctor, typically for a few days until your symptoms improve. Do not use it for more than 7 days without consulting your doctor. Prolonged use can lead to rebound congestion, where symptoms worsen.
How do I dispose of Pseudoephedrine?
Dispose of unused pseudoephedrine by taking it to a drug take-back program or collection site at a pharmacy or hospital. If you can't find a take-back program, you can throw it in the trash at home. First, mix it with something undesirable like used coffee grounds, seal it in a plastic bag, and throw it away.
How do I take Pseudoephedrine?
Take pseudoephedrine as directed by your doctor, usually every 4 to 6 hours. It can be taken with or without food. Do not crush or chew extended-release tablets, as this can release the drug all at once, increasing the risk of side effects. If you miss a dose, take it as soon as you remember unless it's almost time for your next dose. Do not double the dose to catch up. Avoid taking it close to bedtime to prevent trouble sleeping.
How long does it take for Pseudoephedrine to start working?
Pseudoephedrine starts working within 30 minutes to an hour after taking it. You should notice relief from nasal congestion as the medication reduces swelling in your nasal passages. The full effect may take a little longer, depending on individual factors like your overall health. Always take pseudoephedrine as directed for the best results.
How should I store Pseudoephedrine?
Store pseudoephedrine at room temperature, away from moisture and light. Keep it in a tightly closed container. Avoid storing it in humid places like bathrooms, as moisture can affect the medication's effectiveness. Always keep pseudoephedrine out of reach of children to prevent accidental ingestion.
What is the usual dose of Pseudoephedrine?
The usual dose of pseudoephedrine for adults is 60 mg every 4 to 6 hours, not exceeding 240 mg in 24 hours. For children, the dose is based on age and weight, so follow your doctor's instructions. Elderly patients may require a lower dose due to increased sensitivity. Always follow your doctor's specific dosing instructions for your health needs.
Warnings and Precautions
Can I take Pseudoephedrine with other prescription drugs?
Pseudoephedrine can interact with certain medications, increasing the risk of side effects. Avoid using it with MAO inhibitors, as this can cause dangerous increases in blood pressure. It may also interact with other stimulants, increasing nervousness or heart rate. Always inform your doctor about all medications you are taking to prevent interactions.
Can Pseudoephedrine be taken safely while breastfeeding?
Pseudoephedrine is excreted into breast milk in small amounts. It may reduce milk supply and cause irritability in the breastfed infant. Use it cautiously while breastfeeding and only if necessary. Consult your doctor for advice on safer alternatives if you are concerned about its effects on your baby or milk supply.
Can Pseudoephedrine be taken safely while pregnant?
Pseudoephedrine should be used during pregnancy only if clearly needed. Limited evidence is available on its safety during pregnancy. Some studies suggest a possible risk of birth defects if used in the first trimester. Always consult your doctor before using pseudoephedrine during pregnancy to weigh the benefits and risks.
Does Pseudoephedrine have adverse effects?
Adverse effects are unwanted reactions to a medication. Common adverse effects of pseudoephedrine include nervousness, dizziness, and trouble sleeping. These effects are usually mild. Serious side effects, like increased blood pressure or heart rate, require immediate medical attention. If you notice any new or worsening symptoms, contact your doctor.
Does Pseudoephedrine have any safety warnings?
Yes, pseudoephedrine has safety warnings. It can raise blood pressure, so people with hypertension should use it cautiously. It may also cause nervousness, dizziness, or sleeplessness. If you experience these symptoms, stop using the medication and consult your doctor. Avoid using pseudoephedrine if you have severe high blood pressure, heart disease, or are taking MAO inhibitors.
Is it safe to drink alcohol while taking Pseudoephedrine?
It's best to avoid alcohol while taking pseudoephedrine. Alcohol can increase the risk of side effects like dizziness and drowsiness. It may also worsen the medication's effects on blood pressure. If you choose to drink, limit your alcohol intake and watch for any adverse reactions. Consult your doctor for personalized advice.
Is it safe to exercise while taking Pseudoephedrine?
You can exercise while taking pseudoephedrine, but be aware of potential side effects. This medication can cause increased heart rate and blood pressure, which might affect your exercise capacity. If you feel dizzy or lightheaded during physical activity, stop and rest. Consult your doctor if you have concerns about exercising while on pseudoephedrine.
Is it safe to stop Pseudoephedrine?
Pseudoephedrine is usually used for short-term relief of nasal congestion. You can stop taking it once your symptoms improve. There are no withdrawal symptoms associated with stopping pseudoephedrine. However, if you have been using it for an extended period, consult your doctor before stopping to ensure your symptoms are managed effectively.
Is Pseudoephedrine addictive?
Pseudoephedrine is not considered addictive or habit-forming. It does not cause dependency or withdrawal symptoms when you stop taking it. However, misuse or overuse can lead to serious side effects. Always use pseudoephedrine as directed by your doctor and avoid taking more than the recommended dose.
Is Pseudoephedrine safe for the elderly?
Elderly individuals may be more sensitive to the effects of pseudoephedrine, such as increased blood pressure and heart rate. Use it cautiously and under a doctor's supervision. Monitor for any adverse effects, and consult your doctor if you experience any unusual symptoms. Your doctor may adjust the dose to ensure safety.
What are the most common side effects of Pseudoephedrine?
Side effects are unwanted reactions to a medication. Common side effects of pseudoephedrine include nervousness, dizziness, and trouble sleeping. These effects vary from person to person and are usually mild. If you experience new symptoms after starting pseudoephedrine, they might be temporary or unrelated to the medication. Talk with your doctor before stopping any medication.
Who should avoid taking Pseudoephedrine?
Do not use pseudoephedrine if you have severe high blood pressure, heart disease, or are taking MAO inhibitors. These are absolute contraindications due to severe risks. Use caution if you have diabetes, thyroid disorders, or glaucoma, as these are relative contraindications. Always consult your doctor before using pseudoephedrine if you have any of these conditions.