Barinate 60mg Injection 1ml

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Barinate 60mg Injection 1ml

Introduction to Barinate 60mg Injection 1ml

Barinate 60mg Injection 1ml contains Artesunate, which is a medication primarily utilized for the treatment of malaria, particularly in severe cases. Belonging to the artemisinin class of medications holds a place on the World Health Organization's List of Essential Medicines.

It functions as a prodrug, rapidly converting to its active form, dihydroartemisinin (DHA). This transformation generates reactive oxygen species, inducing oxidative stress and causing damage to malarial proteins. Additionally, it inhibits the essential Plasmodium falciparum exported protein 1 (EXP1), reducing parasite glutathione levels.

While generally well-tolerated, common side effects may include a slow heartbeat, allergic reactions, dizziness, and low white blood cell levels In severe cases, kidney failure requiring dialysis, hemoglobinuria (presence of hemoglobin in urine), and jaundice have been reported.

It is considered safe during pregnancy, particularly in the second and third trimesters, although caution is advised in the first trimester. It is generally safe for use in children, with adjustments in dosing for those under 20 kg. Notably, it should be avoided in newborns when combined with sulfadoxine/pyrimethamine due to potential effects on bilirubin.

In the event of a missed dose, it is crucial to consult with a healthcare professional for guidance on the appropriate course of action. The timing and severity of the missed dose will be considered to determine the most suitable response.

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Related Faqs

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Is Arh Plus banned in India?

The availability of this particular medication is restricted to India and can only be obtained with a legitimate prescription from a qualified medical professional It is not accessible overthecounter or through other means without proper authorization This precaution ensures that the medication is used safely and effectively as prescribed by a healthcare provider who has evaluated the individuals specific medical condition and needs Engaging in selfmedication or obtaining the medication without the necessary expertise and supervision can lead to potential risks and adverse effects Therefore it is essential to adhere to the regulations and consult a healthcare practitioner in India to obtain a prescription for this medication By doing so individuals can ensure their health and wellbeing are prioritized while utilizing the medication appropriately for their medical requirements

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How does Barinate work?

The mechanism of action involves the production and release of free radicals that effectively eliminate the malarial parasite known as Plasmodium By generating these highly reactive molecules the medication targets and disrupts crucial components of the parasites life cycle preventing its survival and replication within the human body This oxidative process induced by the medication leads to the destruction of the malarial parasite inhibiting its ability to cause further harm and enabling the bodys immune system to effectively clear the infection This unique mode of action makes the medication a valuable tool in the fight against malaria as it directly targets the parasite while minimizing the risk of developing resistance Additionally the production of free radicals not only plays a pivotal role in combating the malarial infection but also contributes to the medications effectiveness against other types of parasitic infections By specifically targeting the parasites vulnerable structures and pathways this mechanism of action ensures that the medication provides a potent and reliable defense against malaria and related diseases

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Where does Barinate come from?

Artemisinin is a compound that is extracted from the Artemisia annua plant commonly known as the sweet wormwood or qinghao plant This plant has long been used in traditional Chinese medicine for its medicinal properties Artemisinin is specifically derived from the leaves and flowers of the plant through a process of extraction and purification Artemisinin is wellknown for its antimalarial properties It has been used as a key component in the treatment of malaria especially in cases where the disease has become resistant to other medications The compound works by targeting the malaria parasites in the bloodstream effectively killing them and helping to alleviate the symptoms of the disease Apart from its antimalarial benefits artemisinin has also shown promising results in the treatment of other diseases Research suggests that it may have potential in treating certain types of cancers such as breast lung and colorectal cancers Additionally it has also displayed antiinflammatory and immunomodulatory properties which could be beneficial in various autoimmune disorders The extraction and production of artemisinin is a complex process involving careful cultivation of the Artemisia annua plant and precise extraction techniques Due to the growing demand for artemisininbased treatments efforts are being made to increase its production and lower its cost making it more accessible to those in need

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Is Barinate banned in India?

The availability of this specific product in India is limited to individuals who hold a valid prescription from a licensed healthcare practitioner The regulations in place ensure that only those who genuinely require the item for medical purposes can obtain it This approach aims to promote responsible use and prevent misuse or abuse of the product Individuals must consult with a certified medical professional who will assess their condition and prescribe the item if deemed necessary This process helps to safeguard public health and maintain the integrity of the healthcare system By effectively controlling the accessibility of the product the authorities prioritize the wellbeing and safety of individuals in need Therefore it is essential for individuals to adhere to the established guidelines and seek professional medical advice to obtain the item legally and responsibly

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Does artesunate contain sulphur?

There is absolutely no trace of sulphur in this particular product It is completely devoid of any sulphur content This ensures that the product remains free from any sulphurrelated compounds or elements The absence of sulphur in this product is crucial for those individuals who may have allergies or sensitivities to sulphur as it eliminates any potential adverse reactions they may experience Moreover the absence of sulphur also contributes to the overall quality and purity of the product making it suitable for a wider range of consumers Being sulphurfree this product provides a safer and more inclusive option for individuals seeking its benefits without the worry of sulphurrelated issues Rest assured the absence of sulphur in this product upholds its integrity and ensures a reliable and suitable choice for those with specific sulphurrelated concerns or preferences

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Why is artesunate better than quinine?

When it comes to treating certain medical conditions such as malaria the method of administration can play a crucial role in the effectiveness of the treatment In the case of malaria treatment research has shown that injecting artesunate into the muscle or vein has yielded superior results compared to the use of quinine This finding highlights the importance of consulting with a healthcare professional before making any decisions regarding the use of these medications Artesunate a medication known for its antimalarial properties has demonstrated its ability to effectively combat the malaria parasite when administered through intramuscular or intravenous injection These methods of delivery allow the medication to be absorbed directly into the bloodstream enabling it to reach the target area quickly and efficiently As a result artesunate has shown greater treatment efficacy in comparison to quinine another commonly used antimalarial drug However it is crucial to emphasize the significance of consulting a doctor or healthcare provider before considering the use of any medication including artesunate Malaria is a complex disease and its treatment may require a tailored approach based on factors such as the specific type of malaria infection the patients medical history and any potential contraindications Only a qualified healthcare professional can assess these factors and determine the most suitable course of treatment for each individual patient In conclusion while research suggests that intramuscular or intravenous injection of artesunate may offer superior treatment effects compared to quinine for malaria it is essential to seek professional medical advice before initiating any medication regimen By doing so patients can ensure that their treatment plan is specifically tailored to their unique circumstances maximizing the chances of successful recovery

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Published At: Oct 19, 2023

Updated At: Sep 19, 2024

Reviewed By:

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Published At: Oct 19, 2023

Updated At: Sep 19, 2024

Disclaimer : This information is not a substitute for medical advice. Consult your healthcare provider before making any changes to your treatment . Do not ignore or delay professional medical advice based on anything you have seen or read on Medwiki.