Geffy 250mg Tablet 10s (GEFITINIB)
Introduction to Geffy 250mg Tablet 10s
Geffy 250mg Tablet 10s is a medication primarily used to treat a specific type of lung cancer known as non-small cell lung cancer (NSCLC). It is particularly effe... See More
What is Geffy tablet?
Geffy tablet is a targeted therapy used to treat non-small cell lung cancer (NSCLC) in patients with specific EGFR mutations. It works by inhibiting the epidermal growth factor receptor (EGFR), slowing or stopping cancer cell growth. Geffy tablet is mainly prescribed for advanced or metastatic NSCLC and is taken orally once daily. It is more effective in patients whose tumors have EGFR mutations confirmed by genetic testing.
What is the usual dose of Geffy tablet?
The standard dose of Geffy tablet for adults is 250 mg once daily. It is usually taken as a single tablet at the same time each day. It is not commonly used in children, as its safety and efficacy in pediatric patients are not well established. If severe side effects occur, the dose may be adjusted or treatment may be paused, as per the doctor's advice.
How do I take Geffy tablet?
Geffy tablet should be taken once daily, with or without food. The tablet should be swallowed whole with water. If swallowing is difficult, it can be dispersed in a glass of water and consumed immediately. Avoid grapefruit and grapefruit juice, as they can interfere with the drug’s absorption. Also, St. John’s Wort should be avoided, as it may reduce the effectiveness of Geffy tablet.
For how long do I take Geffy tablet?
Geffy tablet is taken as long as it remains effective and the side effects are manageable. Patients may continue treatment for months or years if their cancer does not progress. Regular monitoring with scans and medical tests is required to check whether the medication is working and if any side effects are developing. If the cancer progresses, alternative treatments may be considered.
What disease or symptom is Geffy tablet used for?
Geffy tablet is used for the treatment of non-small cell lung cancer (NSCLC) that is locally advanced or metastatic and has EGFR gene mutations. It is prescribed mainly for patients who have not received prior chemotherapy. This medication is most effective in patients with specific genetic mutations confirmed through EGFR testing. It is not effective in cancers that do not have these mutations.
How long does it take for Geffy tablet to start working?
Geffy tablet starts working within a few weeks, but noticeable improvements are usually seen after several weeks to months of treatment. Tumor shrinkage or symptom relief may take one to three months. Regular imaging tests like CT scans or MRIs are used to monitor progress. Some patients feel better within the first month, while others take longer to respond.
Is Geffy tablet effective?
Clinical studies have shown that Geffy tablet is highly effective in NSCLC patients with EGFR mutations, improving survival rates and quality of life. Studies indicate that progression-free survival (PFS) is longer compared to standard chemotherapy. However, it does not work well for tumors without EGFR mutations. Research shows that patients with mutations exon 19 deletion or exon 21 L858R benefit the most from this treatment.
How do I know if Geffy tablet is working?
Doctors monitor the effectiveness of Geffy tablet using CT scans, MRIs, or PET scans to check for tumor shrinkage. Patients may also notice reduced cancer symptoms like less coughing, improved breathing, and less fatigue. Blood tests and biomarker monitoring may also be used. If the tumor continues to grow, doctors may recommend alternative treatments.
How does Geffy tablet work?
Geffy tablet is an EGFR tyrosine kinase inhibitor (TKI) that blocks signals for cancer cell growth. It specifically targets mutated EGFR receptors, preventing them from sending signals that cause uncontrolled cell division. This leads to tumor shrinkage and slowed progression of NSCLC. It is most effective in tumors with EGFR mutations, as normal EGFR cells are less affected.
Who should avoid taking Geffy tablet?
Geffy tablet should not be taken by people who do not have EGFR mutations, as it will not be effective. It is also not recommended for pregnant or breastfeeding women, people with severe liver or kidney disease, or those with a history of interstitial lung disease. Patients allergic to Geffy tablet or any of its ingredients should avoid this medicine.
Can I take Geffy tablet with other prescription drugs?
Geffy tablet interacts with certain antibiotics, antifungals, and anticonvulsants. Drugs like rifampicin, phenytoin, and carbamazepine can lower its effectiveness. Proton pump inhibitors (PPIs) like omeprazole can reduce absorption. Patients should inform their doctor about all medications they are taking to prevent dangerous interactions.
Can Geffy tablet be taken safely while pregnant?
Geffy tablet is not safe during pregnancy, as it can harm the developing fetus. Animal studies suggest that it may cause birth defects and miscarriage. Women of childbearing age should use effective contraception while taking this medication and for at least two weeks after stopping it. If pregnancy occurs, the doctor should be informed immediately.
Can Geffy tablet be taken safely while breastfeeding?
Geffy tablet is not recommended while breastfeeding because it can pass into breast milk and harm the infant. Women taking Geffy tablet should avoid breastfeeding during treatment and for at least two weeks after stopping the medication.
Is Geffy tablet safe for the elderly?
Geffy tablet can be used in elderly patients, but they may be more prone to side effects like diarrhea, liver issues, and skin rashes. Regular monitoring of liver and kidney function is recommended. Dose adjustments may be needed based on tolerance and side effects.
How should I store Geffy tablet?
Store Geffy tablet at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep it out of reach of children and do not store it in the bathroom. Do not use expired tablets.
Does Geffy tablet make people tired or drowsy?
Geffy tablet does not directly cause drowsiness, but fatigue is a common side effect, affecting 10-15% of patients. This may be due to the body adjusting to the medication or the effects of cancer itself. If fatigue is severe, patients should get adequate rest, avoid driving or operating machinery, and inform their doctor if tiredness persists or worsens.
Does Geffy tablet cause stomach upset?
Yes, Geffy tablet can cause stomach-related side effects such as diarrhea (50-60%), nausea (25%), vomiting (15%), and abdominal pain. If mild, these symptoms can be managed by taking the medication with food and drinking plenty of fluids. If diarrhea is severe, leading to dehydration, or if nausea and vomiting persist, a doctor should be consulted for proper management or dose adjustment.
Does Geffy tablet affect sleep?
Geffy tablet does not commonly cause sleep disturbances, but some patients may experience insomnia or increased fatigue. These effects are usually mild but can impact daily activities. If sleep issues persist, maintaining a proper sleep schedule and avoiding stimulants like caffeine in the evening may help. If sleep problems become severe, consulting a doctor for further evaluation is recommended.
Does Geffy tablet make it hard to think or concentrate?
Geffy tablet does not usually cause major cognitive side effects, but some patients report mild confusion, difficulty concentrating, or memory problems. This may be linked to fatigue or the underlying disease. If cognitive issues become significant, patients should rest, stay hydrated, and seek medical advice if symptoms interfere with daily activities or worsen over time.
Does Geffy tablet affect mood?
Geffy tablet is not directly linked to mood disorders, but some patients report mild anxiety, irritability, or depression. These effects could be related to cancer treatment stress or fatigue. If mood swings become severe or persistent, talking to a doctor or mental health professional can help. Lifestyle changes, stress management, and emotional support may also improve well-being.
Does Geffy tablet interfere with sexual function?
Geffy tablet does not directly cause sexual dysfunction, but side effects like fatigue, nausea, or mood changes may reduce libido. Some patients may experience low energy levels, which can indirectly affect sexual activity. If this becomes a concern, discussing it with a doctor can help. Managing fatigue and emotional well-being may improve overall sexual health and intimacy.
Does Geffy tablet affect appetite?
Yes, loss of appetite is a common side effect of Geffy tablet, occurring in 15-20% of patients. It may be due to nausea, taste changes, or digestive issues. Eating small, frequent meals and staying hydrated can help. If appetite loss leads to significant weight loss or weakness, patients should consult their doctor for dietary support or medication adjustments.
Does Geffy tablet cause weight gain?
Geffy tablet does not usually cause weight gain. In fact, weight loss is more common, as it can reduce appetite and cause diarrhea or nausea. Patients should maintain proper nutrition and hydration. If weight loss is excessive or rapid, a doctor may suggest dietary changes, supplements, or medication adjustments to help maintain a healthy weight.
Does Geffy tablet cause headaches?
Headaches occur in about 10-15% of patients taking Geffy tablet. They are usually mild but can sometimes be persistent. Staying hydrated, managing stress, and using mild pain relievers like paracetamol (if approved by a doctor) may help. If headaches are severe, frequent, or accompanied by other symptoms like dizziness or vision changes, medical advice should be sought.
Does Geffy tablet limit driving?
Geffy tablet does not directly impair driving ability, but side effects like fatigue, dizziness, or blurred vision may make it unsafe to drive. Patients should assess how they feel before driving. If they experience dizziness, drowsiness, or lack of concentration, they should avoid driving and consult their doctor about managing these side effects safely.
Is it safe to drink alcohol while taking Geffy tablet?
Drinking alcohol while on Geffy tablet is not recommended, as alcohol can worsen side effects like liver toxicity, nausea, and fatigue. Even moderate alcohol consumption may put extra stress on the liver, which is already processing the drug. If patients choose to drink occasionally, they should consult their doctor and limit intake to avoid complications.
Is it safe to drink coffee or tea while taking Geffy tablet?
Drinking coffee or tea is generally safe, as caffeine does not directly interact with Geffy tablet. However, excessive caffeine intake may worsen stomach upset, nausea, or insomnia, which some patients already experience as side effects. If caffeine seems to trigger discomfort, reducing intake or switching to decaffeinated beverages may help. Consulting a doctor is advised if symptoms persist.
Is it safe to exercise while taking Geffy tablet?
Yes, light to moderate exercise is generally safe and can help maintain strength and reduce fatigue. However, strenuous activity should be avoided if patients experience fatigue, dizziness, or weakness from Geffy tablet. Walking, yoga, and light stretching are usually well-tolerated. If side effects make exercise difficult, consulting a doctor about adjusting activity levels is recommended.
What are Geffy tablet possible harms and risks?
Common side effects include diarrhea (50-60%), skin rash (40-50%), nausea, vomiting, and loss of appetite. Serious but less common risks include liver toxicity, lung inflammation (interstitial lung disease), and severe diarrhea leading to dehydration. Regular monitoring of liver function tests is required. If severe side effects occur, the dose may need to be reduced or stopped.
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