Gefitinib
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Drug Status
Government Approvals
US(FDA), UK(BNF)
WHO Essential Medicine
YES
Known Teratogen
Definite
Pharmaceutical Class
Kinase Inhibitor
Controlled Drug Substance
No
gefitinib
Summary
Gefitinib is used to treat non-small cell lung cancer, which is a type of lung cancer. It is effective for cancers with specific genetic mutations that respond to this treatment.
Gefitinib works by blocking a protein called epidermal growth factor receptor (EGFR), which helps cancer cells grow and divide. By inhibiting this protein, Gefitinib slows down or stops the growth of cancer cells.
The usual starting dose of Gefitinib for adults is 250 mg once daily. It is taken as a pill, usually at the same time each day, with or without food.
Common side effects of Gefitinib include diarrhea, skin rash, and nausea. These effects vary from person to person and are usually mild to moderate.
Gefitinib can cause serious lung problems, liver damage, and severe skin reactions. It is not recommended for people with severe liver problems or during pregnancy. Always consult your doctor about any concerns before starting Gefitinib.
Indications and Purpose
How does Gefitinib work?
Gefitinib works by blocking a protein called epidermal growth factor receptor (EGFR), which helps cancer cells grow and divide. By inhibiting this protein, Gefitinib slows down or stops the growth of cancer cells. This mechanism makes it effective for treating non-small cell lung cancer with specific genetic mutations.
Is Gefitinib effective?
Gefitinib is effective in treating non-small cell lung cancer, which is a type of lung cancer. It works by blocking a protein that helps cancer cells grow. Clinical studies show Gefitinib can shrink tumors and improve survival rates in patients with specific genetic mutations.
What is Gefitinib?
Gefitinib is a medication used to treat non-small cell lung cancer, which is a type of lung cancer. It belongs to a class of drugs called tyrosine kinase inhibitors, which block proteins that help cancer cells grow. Gefitinib is used when the cancer has specific genetic mutations and is often part of a comprehensive cancer treatment plan.
Directions for Use
For how long do I take Gefitinib?
Gefitinib is usually a long-term medication for managing non-small cell lung cancer. You'll typically take it every day as a continuous treatment unless your doctor suggests otherwise. How long you'll need this medication depends on your body's response and any side effects you experience. Always talk with your doctor before changing or stopping your Gefitinib treatment.
How do I dispose of Gefitinib?
Bring unused Gefitinib to a drug take-back program or collection site at a pharmacy or hospital. If you can't find a take-back program, you can throw it in the trash at home. First, mix it with something undesirable like used coffee grounds, seal it in a plastic bag, and throw it away.
How do I take Gefitinib?
Take Gefitinib as a once-daily pill, usually at the same time each day. You can take it with or without food. If you have trouble swallowing the pill, it can be dissolved in water. If you miss a dose, take it as soon as you remember unless it's almost time for your next dose. Then, skip the missed dose and continue your normal schedule. Never take two doses at once. Always follow your doctor's specific instructions.
How long does it take for Gefitinib to start working?
Gefitinib starts working in your body shortly after you take it, but it may take several weeks to see noticeable effects. The time it takes to achieve full therapeutic effect can vary based on individual factors like your overall health and the specific characteristics of your cancer. Regular monitoring by your doctor will help assess how well the medication is working.
How should I store Gefitinib?
Store Gefitinib at room temperature, away from moisture and light. Keep it in a tightly closed container. Don't store it in humid places like bathrooms. Always keep Gefitinib out of children's reach to prevent accidental swallowing. Check the expiration date regularly and dispose of any unused or expired medication properly.
What is the usual dose of Gefitinib?
The usual starting dose of Gefitinib for adults is 250 mg once daily. It is important to take it at the same time each day. Your doctor may adjust your dose based on your response to the treatment. Always follow your doctor's specific dosing instructions for your personal health needs.
Warnings and Precautions
Can Gefitinib be taken safely while breastfeeding?
Gefitinib is not recommended while breastfeeding. We don't have much information about whether it passes into human breast milk. If you're taking Gefitinib and want to breastfeed, talk with your doctor about safer medication options that would allow you to nurse your baby safely.
Can Gefitinib be taken safely while pregnant?
Gefitinib is not recommended during pregnancy. It can harm an unborn baby. If you're pregnant or planning to become pregnant, talk with your doctor about the safest treatment options. Your doctor can help create a plan that protects both you and your baby.
Can I take Gefitinib with other prescription drugs?
Gefitinib can interact with certain medications, such as warfarin, which is a blood thinner, and phenytoin, which is used for seizures. These interactions can increase the risk of side effects or reduce Gefitinib's effectiveness. Always inform your doctor about all medications you're taking to manage these risks.
Does Gefitinib have adverse effects?
Adverse effects are unwanted reactions to a medication. Common adverse effects of Gefitinib include diarrhea, skin rash, and nausea. Serious effects can include lung problems and liver damage. If you notice any new or worsening symptoms, contact your doctor immediately. Regular monitoring helps manage these risks.
Does Gefitinib have any safety warnings?
Gefitinib has important safety warnings. It can cause serious lung problems, liver damage, and severe skin reactions. If you experience symptoms like difficulty breathing, yellowing of the skin or eyes, or severe skin rash, seek medical help immediately. Regular monitoring by your doctor is important to manage these risks.
Is Gefitinib addictive?
Gefitinib is not addictive or habit-forming. This medication doesn't cause dependency or withdrawal symptoms when you stop taking it. If you have concerns about medication dependence, you can feel confident that Gefitinib doesn't carry this risk while managing your health condition.
Is Gefitinib safe for the elderly?
Elderly patients may be more vulnerable to Gefitinib's side effects, such as diarrhea and skin reactions. Regular monitoring by a doctor is important to manage these risks. Discuss any concerns with your doctor to ensure safe and effective treatment.
Is it safe to drink alcohol while taking Gefitinib?
It's best to avoid alcohol while taking Gefitinib. Alcohol can increase the risk of liver damage, which is a potential side effect of Gefitinib. If you choose to drink, limit your alcohol intake and discuss it with your doctor to get personalized advice based on your health situation.
Is it safe to exercise while taking Gefitinib?
You can exercise while taking Gefitinib, but be cautious. Gefitinib can cause fatigue, which might affect your exercise capacity. Listen to your body and avoid strenuous activities if you feel tired. Stay hydrated and rest if you experience dizziness or unusual fatigue during exercise.
Is it safe to stop Gefitinib?
Stopping Gefitinib suddenly can affect your treatment. If you're taking it for cancer, stopping could allow the cancer to progress. Always talk with your doctor before stopping Gefitinib. They might suggest a gradual reduction or switching to another treatment to manage your condition safely.
What are the most common side effects of Gefitinib?
Side effects are unwanted reactions that can happen when taking a medication. Common side effects of Gefitinib include diarrhea, skin rash, and nausea. These effects vary from person to person. If you notice new symptoms after starting Gefitinib, they might be temporary or unrelated to the medication. Talk with your doctor before stopping any medication.
Who should avoid taking Gefitinib?
Don't take Gefitinib if you're allergic to it or its ingredients. Serious allergic reactions require immediate medical help. Gefitinib is not recommended for people with severe liver problems. Always consult your doctor about any concerns or conditions before starting Gefitinib.
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