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fibisafe (MIFEPRISTONE)

Fibisafe 25mg Tablet is a medication designed to address high blood sugar levels in individuals with Cushing Syndrome.

It plays a pivotal role by blocking the activity of cortisol, a stress-related hor... See More

Available in 2 variations

Fibisafe 25mg Tablet

Mifepristone (25mg)

strip of 10 tablets

MRP : ₹385

Fibisafe 10mg Tablet

Mifepristone (10mg)

strip of 10 tablets

MRP : ₹275

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What is Fibisafe?

Fibisafe is a medication used primarily for medical abortion in early pregnancy and for treating Cushing’s syndrome. It works by blocking progesterone, a hormone needed to maintain pregnancy, leading to the detachment of the pregnancy from the uterus. It is often used with misoprostol to complete the abortion process. In Cushing’s syndrome, it helps reduce high blood sugar by blocking cortisol effects. It is a prescription drug and should be taken under medical supervision.

What is the usual dose of Fibisafe?

For medical abortion, the typical dose is 200 mg taken once, followed by misoprostol (800 mcg) after 24–48 hours. For Cushing’s syndrome, the dose starts at 300 mg per day and may be increased based on response. The dosage may vary depending on the individual’s health condition and should be prescribed by a doctor to ensure safety and effectiveness.

How do I take Fibisafe?

Fibisafe should be taken orally with water. For abortion, it is followed by misoprostol, which helps expel the pregnancy. It is best taken under medical supervision to monitor any complications. Do not take it with grapefruit juice, as it may interfere with absorption. Always follow your doctor’s instructions for the best results and safety.

For how long do I take Fibisafe?

For medical abortion, it is taken as a single dose, followed by misoprostol after 24–48 hours. For Cushing’s syndrome, it is taken daily for long-term management, depending on the patient's response and doctor’s guidance. The duration varies based on the condition being treated, and medical follow-up is necessary to assess effectiveness and any side effects.

What is Fibisafe used for?

Fibisafe is primarily used for medical abortion in pregnancies up to 10 weeks. It is also used to treat Cushing’s syndrome in patients with high blood sugar levels due to excess cortisol. Additionally, it may be used in certain cases of missed miscarriage and as an investigational drug for other hormonal conditions.

How long does it take for Fibisafe to start working?

For abortion, Fibisafe starts working within 24 to 48 hours, causing the pregnancy to detach from the uterus. Misoprostol, taken afterward, induces uterine contractions to expel the pregnancy. For Cushing’s syndrome, the effects may take several weeks to regulate blood sugar and cortisol levels.

Is Fibisafe effective?

Yes, Fibisafe is highly effective for medical abortion, with a success rate of 95-98% when combined with misoprostol. It is also effective in treating Cushing’s syndrome, helping control blood sugar and cortisol levels. However, its effectiveness depends on correct usage and medical supervision.

How does one know if Fibisafe is working?

For abortion, signs include bleeding and cramping within 24–48 hours after taking misoprostol. A follow-up test or ultrasound after 7–14 days confirms success. In Cushing’s syndrome, improvement in blood sugar levels and symptoms indicates effectiveness. If no changes occur, consult a doctor for further evaluation.

How does Fibisafe work?

Fibisafe works by blocking progesterone, a hormone needed for pregnancy. This causes the uterine lining to break down, making it unsuitable for pregnancy. In Cushing’s syndrome, it blocks cortisol receptors, helping reduce high blood sugar levels. Its action depends on the condition being treated.

Who should avoid taking Fibisafe?

Women with ectopic pregnancy, bleeding disorders, severe anemia, or adrenal insufficiency should avoid it. It is also not recommended for those with liver disease, kidney problems, or heart conditions. Always consult a doctor before taking Fibisafe to ensure it is safe based on your health condition.

Can I take Fibisafe with vitamins or supplements?

Some vitamins and supplements, like St. John’s Wort, may reduce its effectiveness. Avoid grapefruit juice and high-dose vitamin C, as they can interfere with absorption. Always check with your doctor before taking supplements with Fibisafe.

Can I take Fibisafe with other prescription drugs?

Fibisafe interacts with anticoagulants, corticosteroids, antifungal drugs, and certain antibiotics, affecting its function. If you take other medications, consult a doctor to avoid harmful interactions. It is essential to disclose all medicines before starting treatment.

Can Fibisafe be taken safely while pregnant?

No, Fibisafe is used to terminate pregnancy and should not be taken by women wanting to continue pregnancy. If mistakenly taken, seek immediate medical help to assess the situation and possible complications.

Can Fibisafe be taken safely while breastfeeding?

Fibisafe may pass into breast milk, but its effects on infants are unclear. It is advised to pump and discard breast milk for a few days after taking it. Consult a doctor before using it while breastfeeding.

Is Fibisafe safe for the elderly?

Fibisafe is not commonly used in elderly patients except for Cushing’s syndrome. If prescribed, close monitoring is needed for liver function, blood sugar, and potential side effects. Always consult a doctor before use.

How should I store Fibisafe?

Store at room temperature (20–25°C) in a dry place, away from light and moisture. Keep it out of reach of children. Do not use expired medication, as it may lose effectiveness.

Does Fibisafe make people tired or drowsy?

Some people may experience fatigue or dizziness after taking Fibisafe. If this happens, rest and avoid activities requiring alertness, like driving, until the symptoms go away.

Does Fibisafe cause stomach upset?

Yes, nausea, vomiting, and diarrhea are common side effects. Taking it with water and resting can help. If symptoms are severe, consult a doctor for medical advice.

Does Fibisafe affect sleep?

Some people experience insomnia or disrupted sleep after taking Fibisafe. If this occurs, maintain a relaxing bedtime routine and avoid caffeine. If severe, consult a doctor.

Does Fibisafe make it hard to think or concentrate?

In rare cases, Fibisafe may cause dizziness or confusion. If this affects daily activities, avoid driving or operating machinery and seek medical advice if symptoms persist.

Does Fibisafe affect mood?

Some users report anxiety, mood swings, or irritability after taking Fibisafe. These effects are usually temporary. If mood changes are severe or persistent, consult a healthcare provider.

Does Fibisafe interfere with sexual function?

Fibisafe is not known to directly affect libido or sexual performance, but its emotional and physical effects may temporarily reduce interest in sexual activity.

Does Fibisafe affect appetite?

Some users may experience loss of appetite, while others report increased hunger due to hormonal changes. Eating balanced meals and staying hydrated can help manage these effects.

Does Fibisafe cause weight gain?

Weight changes are not common, but some people may experience fluid retention or bloating. If significant weight gain occurs, consult a doctor for advice.

Does Fibisafe cause headaches?

Yes, mild to moderate headaches are a possible side effect. Staying hydrated and resting may help. If severe, seek medical advice.

Does Fibisafe limit driving?

Fibisafe may cause dizziness, lightheadedness, tiredness, weakness, and nausea. This can make it difficult to drive or do other tasks that require your full attention. Talk to your doctor about whether it is safe for you to drive or do other activities while taking this medication.

Is it safe to drink alcohol while taking Fibisafe?

Alcohol may increase dizziness, nausea, and liver strain. It is best to avoid alcohol while taking Fibisafe.

Is it safe to drink coffee or tea while taking Fibisafe?

Caffeine does not interact directly but may worsen nausea or anxiety. If sensitive, limit intake while taking Fibisafe.

Is it safe to exercise while taking Fibisafe?

Light activity is fine, but avoid heavy exercise if you feel weak, dizzy, or have heavy bleeding. Listen to your body and rest if needed.

What are Fibisafe possible harms and risks?

Common side effects include nausea, vomiting, cramping, diarrhea, headache, and dizziness. Serious risks include excessive bleeding, infection, and incomplete abortion, requiring medical attention. In rare cases, severe allergic reactions can occur. Monitoring and follow-up with a doctor help manage these risks effectively.