Mifepristone
Ectopic Pregnancy, Brain Neoplasms ... show more
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Drug Status
Government Approvals
US(FDA), UK(BNF)
WHO Essential Medicine
NO
Known Teratogen
No
Pharmaceutical Class
Progestin Antagonist
Controlled Drug Substance
No
mifepristone
Summary
Mifepristone is used for the medical termination of early pregnancy. It is not used for other conditions or symptoms.
Mifepristone works by blocking progesterone, which is a hormone necessary for pregnancy to continue. Without progesterone, the pregnancy cannot continue.
The usual dose of Mifepristone is a single 200 mg tablet taken orally with water. It is typically used with another medication called misoprostol.
Common side effects of Mifepristone include nausea, vomiting, and cramping. These effects are usually mild and temporary.
Mifepristone should not be used if you have an ectopic pregnancy, which is a pregnancy outside the uterus, or if you have an allergy to the medication. Consult your doctor for safety.
Indications and Purpose
How does Mifepristone work?
Mifepristone works by blocking the hormone progesterone, which is necessary for pregnancy to continue. Without progesterone, the lining of the uterus breaks down, and the pregnancy cannot continue. This process is similar to how a plant wilts without water. Mifepristone is used with misoprostol to effectively end a pregnancy.
Is Mifepristone effective?
Mifepristone is effective for medical termination of early pregnancy. It works by blocking the hormone progesterone, which is necessary for pregnancy to continue. Clinical studies show that Mifepristone, when used with misoprostol, is highly effective in ending early pregnancies. If you have questions about its effectiveness for your specific situation, talk with your doctor.
What is Mifepristone?
Mifepristone is a medication used for medical termination of early pregnancy. It belongs to a class of drugs called antiprogestins, which block the hormone progesterone necessary for pregnancy to continue. Mifepristone is used in combination with another medication called misoprostol to end a pregnancy. It is not used for other conditions or symptoms.
Directions for Use
For how long do I take Mifepristone?
Mifepristone is usually taken as a single dose for medical termination of pregnancy. It's not intended for long-term use. Follow your doctor's instructions carefully. If you have questions about the duration of use for your specific situation, consult your healthcare provider for guidance.
How do I dispose of Mifepristone?
To dispose of Mifepristone, return any unused medication to a drug take-back program or collection site at a pharmacy or hospital. If this isn't possible, you can dispose of it in the trash at home. Remove it from its original container, mix it with something undesirable like used coffee grounds, seal it in a plastic bag, and throw it away. This helps prevent harm to people and the environment.
How do I take Mifepristone?
Mifepristone is usually taken as a single dose. It's important to follow your doctor's instructions on how to take it. You should take Mifepristone with a glass of water. Do not crush or chew the tablet. It's best to take it on an empty stomach, which means not eating for a few hours before and after taking the medication. If you miss a dose, contact your healthcare provider for advice. Always follow your doctor's specific instructions for taking Mifepristone.
How long does it take for Mifepristone to start working?
Mifepristone begins working within a few hours after taking it. The full effect, which includes cramping and bleeding, usually occurs within 24 to 48 hours. The time it takes to work can vary based on individual factors like your body's response and the stage of pregnancy. Always follow your doctor's instructions for the best results.
How should I store Mifepristone?
Store Mifepristone at room temperature, away from moisture and light. Keep it in its original container, tightly closed, and out of reach of children. Do not store it in the bathroom, where humidity can affect the medication. Always check the expiration date and properly dispose of any unused or expired medication.
What is the usual dose of Mifepristone?
The usual dose of Mifepristone for adults is a single 200 mg tablet taken orally. This medication is typically used in combination with another medicine called misoprostol for medical termination of pregnancy. Always follow your doctor's specific dosing instructions. Dose adjustments may be necessary for special populations, so it's important to consult your healthcare provider for personalized advice.
Warnings and Precautions
Can I take Mifepristone with other prescription drugs?
Mifepristone can interact with certain medications, such as corticosteroids, which are used to reduce inflammation, and anticoagulants, which are blood thinners. These interactions can increase the risk of adverse effects. Always inform your doctor about all medications you are taking to avoid potential interactions. Your doctor can help manage any risks and adjust your treatment plan if necessary.
Can Mifepristone be taken safely while breastfeeding?
Mifepristone is not recommended while breastfeeding. There is limited information on whether it passes into breast milk, but due to its effects, it's best to avoid using it while nursing. If you need to take Mifepristone and are breastfeeding, talk with your doctor about safer alternatives or temporary cessation of breastfeeding.
Can Mifepristone be taken safely while pregnant?
Mifepristone is used specifically for medical termination of pregnancy and is not safe for use during a continuing pregnancy. It works by blocking the hormone progesterone, which is necessary for pregnancy to continue. If you are pregnant and wish to continue the pregnancy, do not take Mifepristone. Always consult your doctor for guidance on medication use during pregnancy.
Does Mifepristone have adverse effects?
Adverse effects are unwanted reactions to a medication. With Mifepristone, common adverse effects include nausea, vomiting, and cramping. These effects are usually mild and temporary. Serious adverse effects, like heavy bleeding or infection, are rare but require immediate medical attention. If you experience any new or worsening symptoms, contact your doctor. They can help determine if these symptoms are related to Mifepristone and provide appropriate care.
Does Mifepristone have any safety warnings?
Yes, Mifepristone has important safety warnings. It is used for medical termination of pregnancy and should not be used if you have an ectopic pregnancy, which is a pregnancy outside the uterus. Not following safety warnings can lead to serious health risks. If you experience severe abdominal pain, heavy bleeding, or signs of infection, seek medical help immediately. Always follow your doctor's instructions and discuss any concerns with them.
Is it safe to drink alcohol while taking Mifepristone?
It's best to avoid alcohol while taking Mifepristone. Alcohol can increase the risk of side effects like nausea and dizziness. It may also interfere with the medication's effectiveness. If you choose to drink, limit your intake and watch for any adverse reactions. Always consult your doctor for personalized advice regarding alcohol consumption while on Mifepristone.
Is it safe to exercise while taking Mifepristone?
It's generally safe to exercise while taking Mifepristone, but listen to your body. The medication can cause cramping and bleeding, which might make exercise uncomfortable. Avoid strenuous activities and high-impact sports until you feel better. Light activities like walking can be beneficial. If you experience dizziness or severe discomfort, stop exercising and rest. Consult your doctor if you have concerns about exercising while on Mifepristone.
Is it safe to stop Mifepristone?
Mifepristone is usually taken as a single dose for medical termination of pregnancy, so stopping it isn't typically a concern. However, if you have any questions or concerns about your treatment, it's important to talk with your doctor. They can provide guidance and ensure your health and safety are prioritized.
Is Mifepristone addictive?
Mifepristone is not addictive or habit-forming. It does not cause dependency or withdrawal symptoms. Mifepristone works by blocking the hormone progesterone, which is necessary for pregnancy to continue. This mechanism does not affect brain chemistry in ways that could lead to addiction. You won't experience cravings for this medication or feel compelled to take more than prescribed. If you have concerns about medication dependence, Mifepristone does not carry this risk.
Is Mifepristone safe for the elderly?
Mifepristone can be used by elderly patients, but they may be more vulnerable to side effects due to age-related health changes. It's important for elderly patients to be closely monitored by their healthcare provider when using Mifepristone. Discuss any existing health conditions with your doctor to ensure the medication is safe for you.
What are the most common side effects of Mifepristone?
Side effects are unwanted reactions to a medication. Common side effects of Mifepristone include nausea, vomiting, and cramping. These effects are usually mild and temporary. If you experience new symptoms after starting Mifepristone, they might be temporary or unrelated to the medication. It's important to talk with your doctor before stopping any medication. They can help determine if your symptoms are related to Mifepristone and provide guidance.
Who should avoid taking Mifepristone?
Mifepristone should not be used if you have an ectopic pregnancy, which is a pregnancy outside the uterus, or if you have an allergy to the medication. It is also contraindicated in people with chronic adrenal failure, which is when the adrenal glands don't produce enough hormones. Always consult your doctor to ensure Mifepristone is safe for you.
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