Terbinafine
Chronic Mucocutaneous Candidiasis, Tinea Pedis ... show more
DRUG STATUS
Approvals
US(FDA), UK(BNF)
Essential Medicine
YES
Teratogenicity
Unlisted
Pharmaceutical Class
Allylamine Antifungal
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Terbinafine
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Click HereSummary
Terbinafine is an antifungal medication used to treat various fungal infections. These include athlete's foot, ringworm, jock itch, and nail infections.
Terbinafine works by inhibiting an enzyme in the fungus that is necessary for its cell membrane. This action either kills the fungus or stops its growth.
Terbinafine is typically taken by mouth in tablet form. The duration of treatment depends on the type of infection. For skin infections, it's generally 2 to 4 weeks, and for nail infections, it can last 6 to 12 weeks. Always follow your doctor's instructions.
Some common side effects of Terbinafine include gastrointestinal symptoms like nausea, diarrhea, or stomach pain, headaches, and changes in taste or loss of taste. Some people may also experience skin rashes or reactions.
People with liver disease, kidney disease, or allergies to terbinafine or similar antifungals should avoid taking Terbinafine. It's also not recommended during pregnancy, especially in the first trimester, and while breastfeeding. Always consult a doctor if you have any underlying health conditions.
Indications and Purpose
What is Terbinafine used for?
It is used to treat various fungal infections, including:
- Athlete's foot
- Ringworm
- Jock itch
- Nail infections (onychomycosis)
How does Terbinafine work?
Terbinafine works by inhibiting an enzyme in the fungus that is necessary for its cell membrane, which ultimately kills the fungus or stops its growth. It targets the fungal cell wall and disrupts its integrity.
Is Terbinafine effective?
Yes, Terbinafine is effective for treating many types of fungal infections, especially those of the skin and nails. It works by killing the fungi or stopping their growth.
How does one know if Terbinafine is working?
You should notice improvement in symptoms such as reduced itching, redness, or scaling in the case of skin infections. For nail infections, it may take several weeks, but you should see healthier nails growing out as the treatment works. It’s important to complete the full course of treatment, even if symptoms improve before then.
Directions for Use
What is the usual dose of Terbinafine?
Terbinafine tablets are a medicine for fungal infections. Doctors decide the correct amount and how long to take it, as it depends on the infection. There's no standard dose, and it's not safe to use in children without a doctor's guidance. You should always talk to a doctor before taking this medicine.
How do I take Terbinafine?
Terbinafine is usually taken by mouth in the form of a tablet. It is best taken with food to improve absorption.
For how long do I take Terbinafine?
The duration of treatment depends on the type of infection:
- Skin infections: Generally 2 to 4 weeks.
- Nail infections: Treatment can last 6 to 12 weeks.
How long does it take for Terbinafine to start working?
You may start to notice improvement in symptoms within a few days to a week, but for nail infections, it may take several weeks to months before the full effect is seen.
How should I store Terbinafine?
Store Terbinafine tablets at room temperature (around 68-77°F or 20-25°C), away from moisture, heat, and light. Keep it in its original packaging and out of reach of children.
Warnings and Precautions
Who should avoid taking Terbinafine?
People who should avoid taking Terbinafine include:
- Those with liver disease or a history of liver problems
- People with kidney disease
- People who are allergic to terbinafine or similar antifungals
Always consult a doctor if you have any underlying health conditions.
Can I take Terbinafine with other prescription drugs?
Terbinafine may interact with some medications. For example:
- It can interact with cimetidine (an acid reducer) or rifampin (an antibiotic), which can alter how Terbinafine works in your body.
- It may also interact with certain medications used for heart conditions or antifungal drugs.
Always inform your healthcare provider about all other medications you are taking to avoid potential drug interactions.
Can I take Terbinafine with vitamins or supplements?
Generally, Terbinafine can be taken with most vitamins or supplements, but some supplements (like those that affect liver function) may interact with it. It's a good idea to inform your doctor about any vitamins, minerals, or supplements you are taking to ensure there are no interactions.
Can Terbinafine be taken safely while pregnant?
Terbinafine should generally be avoided during pregnancy, especially in the first trimester, as it is not considered entirely safe. Consult your doctor for advice, and they may recommend an alternative antifungal medication if needed.
Can Terbinafine be taken safely while breastfeeding?
Terbinafine is not recommended while breastfeeding because it can pass into breast milk. Discuss alternatives with your doctor if you are breastfeeding.
Is Terbinafine safe for the elderly?
Yes, Terbinafine can be used by elderly individuals, but they may be more susceptible to side effects, especially liver-related issues. Doctors may monitor liver function more closely in older adults. Always follow the doctor’s instructions.
Is it safe to exercise while taking Terbinafine?
Exercise is generally safe while taking Terbinafine, as long as you are feeling well. However, if you experience side effects like dizziness, fatigue, or muscle pain, it’s best to rest and consult your doctor before engaging in vigorous physical activity.
Is it safe to drink alcohol while taking Terbinafine?
It's best to avoid alcohol while taking Terbinafine, especially because Terbinafine can affect liver function, and alcohol can further strain the liver. Drinking alcohol while on Terbinafine can increase the risk of liver damage.