Mebendazole

What is Mebendazole used for?

Mebendazole is used to treat infections caused by intestinal worms, including:

• Pinworms (Enterobiasis)
• Roundworms (Ascariasis)
• Whipworms (Trichuriasis)
• Hookworms (Ancylostomiasis and Necatoriasis)It helps eliminate these parasites by preventing them from absorbing nutrients, leading to their death.

How does Mebendazole work?

Mebendazole works by blocking the worms' ability to absorb glucose (sugar). Since worms rely on glucose for energy, they become weaker, unable to move, and eventually die. The dead worms are then expelled naturally from the body through bowel movements.

Is Mebendazole effective?

Yes, mebendazole is highly effective against most intestinal worms, with cure rates of 90% or higher in many cases. However, reinfection is common, especially with pinworms, so hygiene measures (like washing hands, cleaning clothes, and trimming fingernails) are necessary to prevent worms from returning.

How does one know if Mebendazole is working?

You will know mebendazole is working when symptoms improve, such as reduced itching, stomach pain, or diarrhea. Dead worms may be seen in stool after a few days. If symptoms persist after 3 weeks, consult a doctor to check if a second dose is needed.

What is the usual dose of Mebendazole?

For adults and children over 2 years old, the usual dose depends on the infection:

• Pinworms: A single dose of 100 mg, repeated after 2 weeks if needed.
• Other worms (roundworms, whipworms, hookworms): 100 mg twice daily for 3 days.Children under 2 years old should not take mebendazole unless advised by a doctor.

How do I take Mebendazole?

Mebendazole is usually taken by mouth as a chewable tablet or liquid. It can be taken with or without food. The tablet should be chewed completely before swallowing. No special diet is required, but maintaining good hygiene (like washing hands and cleaning bedding) helps prevent reinfection.

For how long do I take Mebendazole?

The duration of treatment depends on the type of worm infection:

• Pinworm infections: A single dose, repeated after two weeks if reinfection occurs.
• Other worm infections: Taken for 3 consecutive days.Follow your doctor's advice, and if symptoms persist, a second course of treatment may be needed.

How long does it take for Mebendazole to start working?

Mebendazole starts working within a few hours of taking the dose, but it may take a few days to a week for worms to be fully cleared from the intestines. Some people may see dead worms in their stool within 1–3 days after taking the medication.

How should I store Mebendazole?

Mebendazole should be stored at room temperature (20–25°C) in a dry place, away from moisture, heat, and direct sunlight. Keep the bottle tightly closed and out of reach of children. Do not use expired medication.

Who should avoid taking Mebendazole?

People who should avoid mebendazole include:

• Pregnant women (especially in the first trimester)
• Children under 2 years old, unless advised by a doctor
• Those with severe liver disease
• People allergic to mebendazole or similar drugs

Always consult a doctor before use.

Can I take Mebendazole with other prescription drugs?

Mebendazole may interact with:

• Metronidazole (Flagyl) – increases risk of serious skin reactions
• Cimetidine (for acid reflux) – may increase mebendazole levels in the blood
• Anticonvulsants (like carbamazepine) – may reduce effectiveness of mebendazoleAlways inform your doctor about other medications before taking mebendazole.

Can I take Mebendazole with vitamins or supplements?

Yes, mebendazole does not have major interactions with most vitamins or supplements. However, it is recommended to avoid high-fat meals and grapefruit juice, as they can affect absorption. If taking iron supplements, consult your doctor, as some anthelmintics can lower iron levels.

Can Mebendazole be taken safely while pregnant?

Mebendazole is not recommended in pregnancy, especially in the first trimester, due to a potential risk to the developing baby. If treatment is necessary, doctors may prescribe a different medication. Pregnant women should discuss the risks and benefits with their doctor before use.

Can Mebendazole be taken safely while breastfeeding?

Mebendazole is considered safe during breastfeeding, as only a small amount passes into breast milk. However, since data is limited, breastfeeding mothers should consult a doctor before use. If taken, monitor the baby for any side effects like diarrhea or irritability.

Is Mebendazole safe for the elderly?

Yes, mebendazole is generally safe for elderly patients, but those with liver disease should use caution. The drug is metabolized in the liver, so older adults with weakened liver function may require monitoring for potential side effects.

Is it safe to exercise while taking Mebendazole?

Yes, exercise is safe while taking mebendazole. However, if you experience stomach pain, dizziness, or fatigue, take it easy until you feel better. Also, ensure proper hydration and avoid strenuous workouts if you are feeling weak due to the worm infection or side effects of the medication.

Is it safe to drink alcohol while taking Mebendazole?

It is best to avoid alcohol while taking mebendazole. Alcohol can irritate the stomach and liver, increasing the risk of side effects like nausea and dizziness. While occasional drinking is unlikely to cause harm, it is safer to wait until your treatment is finished before consuming alcohol.