Ibuprofen
Rheumatoid Arthritis, Ankylosing Spondylitis ... show more
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DRUG STATUS
Government Approvals
US(FDA), UK(BNF)
WHO Essential Medicine
YES
Known Teratogen
Unlisted
Pharmaceutical Class
Nonsteroidal Anti-inflammatory Drug
Ibuprofen
Learn more about this medicine -
Click HereSummary
Ibuprofen is used to treat various conditions such as headaches, muscle pain, toothaches, menstrual cramps, minor injuries, arthritis, tendonitis, and other inflammatory conditions. It's also used to reduce fever caused by infections or other conditions.
Ibuprofen works by inhibiting enzymes called cyclooxygenase (COX) which are responsible for producing chemicals called prostaglandins that cause inflammation, pain, and fever. By blocking these enzymes, ibuprofen reduces these symptoms.
For adults, the usual dosage of ibuprofen is 200 to 400 mg every 4 to 6 hours as needed. The maximum daily dose is 1200 mg for over-the-counter use and up to 2400 mg for prescription use. It's taken orally, ideally with food or milk to reduce stomach irritation.
Common side effects of ibuprofen include stomach upset, nausea, dizziness, and headache. More serious effects can include gastrointestinal bleeding, ulcers, kidney damage, and increased risk of heart attack or stroke with long-term use. Allergic reactions such as skin rashes or swelling are also possible.
Ibuprofen should not be used by individuals with a history of gastrointestinal bleeding, ulcers, severe kidney or liver disease, or heart conditions such as heart failure. It's also not recommended for pregnant individuals, especially in the third trimester. Caution is advised for people with high blood pressure, asthma, or a history of allergic reactions to NSAIDs.
Indications and Purpose
What is Ibuprofen used for?
Ibuprofen is indicated for relieving pain, tenderness, swelling, and stiffness caused by osteoarthritis and rheumatoid arthritis. It is also used for mild to moderate pain, including menstrual pain, headaches, muscle aches, and pain from the common cold or toothaches.
How does Ibuprofen work?
Ibuprofen works by inhibiting the enzyme cyclooxygenase, which reduces the production of prostaglandins, substances that cause pain, inflammation, and fever. This action helps relieve symptoms associated with various conditions.
Is Ibuprofen effective?
Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that effectively relieves pain, reduces inflammation, and lowers fever by inhibiting the production of substances in the body that cause these symptoms. It is widely used for conditions like arthritis, headaches, and menstrual pain.
How does one know if Ibuprofen is working?
The benefit of ibuprofen is evaluated by monitoring the relief of symptoms such as pain, inflammation, and fever. Regular check-ups with a doctor can help assess its effectiveness and adjust the dosage if necessary.
Directions for Use
What is the usual dose of Ibuprofen?
For adults, the usual dose of ibuprofen is one tablet up to three times a day as needed, with no more than three tablets in a 24-hour period. For children, the dose is based on weight and age, and it's important to follow the dosing chart provided on the medication packaging or consult a doctor. Children should not take more than four doses in 24 hours.
How do I take Ibuprofen?
Ibuprofen can be taken with food or milk to prevent stomach upset. Follow the directions on the package or prescription label carefully, and do not take more or less than directed. There are no specific food restrictions, but avoid alcohol to reduce the risk of stomach bleeding.
For how long do I take Ibuprofen?
Ibuprofen is typically used for short-term relief of pain and inflammation. For pain, it should not be used for more than 10 days unless directed by a doctor. For fever, it should not be used for more than 3 days. Always follow your doctor's instructions for duration of use.
How long does it take for Ibuprofen to start working?
Ibuprofen typically starts working within 30 minutes to an hour after taking it. However, the full effect may take longer depending on the condition being treated.
How should I store Ibuprofen?
Store ibuprofen in its original container, tightly closed, at room temperature, away from excess heat and moisture. Keep it out of reach of children and dispose of unneeded medication through a take-back program.
Warnings and Precautions
Who should avoid taking Ibuprofen?
Important warnings for ibuprofen include the risk of heart attack, stroke, and gastrointestinal bleeding. It should not be used by individuals with a history of heart disease, recent heart surgery, or gastrointestinal issues without consulting a doctor. Always follow the prescribed dosage and duration.
Can I take Ibuprofen with other prescription drugs?
Significant drug interactions with ibuprofen include anticoagulants, other NSAIDs, oral steroids, SSRIs, and SNRIs. These can increase the risk of bleeding or other side effects. Always inform your doctor of all medications you are taking.
Can I take Ibuprofen with vitamins or supplements?
From all available and reliable information, there is no confirmed data on this. Please consult a doctor for personalized advice.
Can Ibuprofen be taken safely while pregnant?
Ibuprofen should be avoided during pregnancy, especially after 20 weeks, as it may harm the fetus and cause complications during delivery. Consult your doctor for alternatives and personalized advice if you are pregnant or planning to become pregnant.
Can Ibuprofen be taken safely while breastfeeding?
Ibuprofen is generally considered safe to use while breastfeeding, as it appears in breast milk in very low concentrations. However, it's always best to consult your doctor for personalized advice.
Is Ibuprofen safe for the elderly?
Elderly individuals may have an increased risk of adverse reactions to ibuprofen, especially gastrointestinal bleeding and perforation. It's important to use the lowest effective dose for the shortest duration necessary and consult a doctor for personalized advice.
Is it safe to exercise while taking Ibuprofen?
Ibuprofen does not typically limit the ability to exercise. However, if you experience any side effects such as dizziness or shortness of breath, it may be best to avoid strenuous activities and consult your doctor.
Is it safe to drink alcohol while taking Ibuprofen?
Drinking alcohol while taking ibuprofen can increase the risk of stomach bleeding and other gastrointestinal issues. It's advisable to limit alcohol consumption to reduce these risks. If you have concerns, consult your doctor for personalized advice.
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