Cimetidine

English

Brand Name :

Tymidin 200mg Tablet , C Met 400mg Tablet ... show more

Approved Treatment Indication :

Peptic Esophagitis, Duodenal Ulcer ... show more

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Summary

What conditions is Cimetidine used for?
Cimetidine is used to treat conditions like ulcers, gastroesophageal reflux disease (GERD), and heartburn. It can also help prevent ulcers caused by nonsteroidal anti-inflammatory drugs.
How does Cimetidine work in the body?
Cimetidine works by blocking histamine receptors in the stomach lining. This decreases the production of stomach acid, relieving symptoms like heartburn and allowing ulcers to heal.
What are the usual dosages and routes of administration for Cimetidine?
Cimetidine is typically taken orally, with or without food. The usual dose for adults is 800-1600 mg per day, divided into two to four doses. Always follow your doctor's instructions.
What are the most commonly observed adverse effects of Cimetidine?
Common side effects of Cimetidine include diarrhea, headache, dizziness, and tiredness. Rare but serious effects can include confusion, liver problems, or low white blood cell counts.
What are important safety warnings and contraindications for Cimetidine?
Cimetidine should not be used by individuals allergic to it, pregnant or breastfeeding women without doctor approval, or those with severe kidney or liver disease. It can interact with certain drugs and supplements, so share your medication list with your doctor. If you experience side effects like sleep disturbances, mood changes, or cognitive issues, contact your doctor.

Approvals

US(FDA), UK(BNF)

Essential Medicine

YES

Teratogenicity

Unlisted

Pharmaceutical Class

Histamine-2 Receptor Antagonist

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Drug Ingredient

Cimetidine

Know More About This Medicine -

Summary

What conditions is Cimetidine used for?
Cimetidine is used to treat conditions like ulcers, gastroesophageal reflux disease (GERD), and heartburn. It can also help prevent ulcers caused by nonsteroidal anti-inflammatory drugs.
How does Cimetidine work in the body?
Cimetidine works by blocking histamine receptors in the stomach lining. This decreases the production of stomach acid, relieving symptoms like heartburn and allowing ulcers to heal.
What are the usual dosages and routes of administration for Cimetidine?
Cimetidine is typically taken orally, with or without food. The usual dose for adults is 800-1600 mg per day, divided into two to four doses. Always follow your doctor's instructions.
What are the most commonly observed adverse effects of Cimetidine?
Common side effects of Cimetidine include diarrhea, headache, dizziness, and tiredness. Rare but serious effects can include confusion, liver problems, or low white blood cell counts.
What are important safety warnings and contraindications for Cimetidine?
Cimetidine should not be used by individuals allergic to it, pregnant or breastfeeding women without doctor approval, or those with severe kidney or liver disease. It can interact with certain drugs and supplements, so share your medication list with your doctor. If you experience side effects like sleep disturbances, mood changes, or cognitive issues, contact your doctor.

Indications and Purpose

What is Cimetidine used for?

Cimetidine treats stomach and duodenal ulcers, GERD, Zollinger-Ellison syndrome, and heartburn. It may also help prevent ulcers caused by nonsteroidal anti-inflammatory drugs (NSAIDs).

How does Cimetidine work?

Cimetidine is an H2 receptor blocker that inhibits histamine in the stomach lining. This reduces acid secretion, allowing the stomach lining to heal and preventing further damage.

Is Cimetidine effective?

Yes, Cimetidine is effective at reducing stomach acid and treating related conditions. It has been widely used and studied, showing significant results in healing ulcers and relieving heartburn symptoms.

How does one know if Cimetidine is working?

You’ll notice reduced symptoms such as less heartburn or stomach pain. Regular check-ups may include tests or endoscopy to confirm healing, particularly in ulcers.

Directions for Use

What is the usual dose of Cimetidine?

For adults, the typical dose is 800–1600 mg daily, divided into two to four doses. Pediatric doses vary based on weight and specific conditions. Always follow your doctor’s prescribed dosage.

How do I take Cimetidine?

Cimetidine is taken orally, with or without food, typically once at bedtime or twice daily. Follow your doctor's instructions. Avoid taking it with alcohol or highly acidic beverages like orange juice.

For how long do I take Cimetidine?

The duration depends on your condition. For ulcers, treatment may last 4–8 weeks. For GERD or heartburn, it’s taken as needed or as prescribed for long-term maintenance.

How long does it take for Cimetidine to start working?

Cimetidine typically starts reducing stomach acid within 1 to 2 hours after a dose. For ulcers, symptom relief can take a few days, and full healing may require several weeks.

How should I store Cimetidine?

Store Cimetidine in a cool, dry place away from moisture and direct sunlight. Keep it out of reach of children and pets.

Warnings and Precautions

Who should avoid taking Cimetidine?

It is not recommended for individuals allergic to it, pregnant or breastfeeding women without doctor approval, or those with severe kidney or liver disease. Always consult your doctor before use.

Can I take Cimetidine with other prescription drugs?

Cimetidine interacts with certain drugs, including warfarin, phenytoin, and theophylline, by altering their metabolism. Share your medication list with your doctor to avoid harmful interactions.

Can I take Cimetidine with vitamins or supplements?

Some supplements, like iron or calcium, may reduce the effectiveness of Cimetidine. Take them at least 2 hours apart and check with your doctor about potential interactions.

Can Cimetidine be taken safely while pregnant?

Cimetidine may be used in pregnancy if benefits outweigh risks, but only under a doctor’s guidance. Safer alternatives like antacids may be preferred.

Can Cimetidine be taken safely while breastfeeding?

Cimetidine passes into breast milk in small amounts. Consult your doctor to weigh the benefits and risks before using it while breastfeeding.

Is Cimetidine safe for the elderly?

Yes, but older adults may be more susceptible to side effects like confusion. Doses may need adjustment to reduce these risks.

Is it safe to exercise while taking Cimetidine?

Yes, light to moderate exercise is safe. However, avoid activities that may worsen acid reflux, like high-intensity exercises, shortly after eating. Adjust based on your condition.

Is it safe to drink alcohol while taking Cimetidine?

Limit alcohol as it can irritate the stomach and reduce the effectiveness of Cimetidine. Occasional alcohol consumption should be discussed with your doctor.