Bromocriptine
Parkinson Disease, Acromegaly ... show more
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DRUG STATUS
Approvals
US(FDA), UK(BNF)
Essential Medicine
YES
Teratogenicity
Unlisted
Pharmaceutical Class
Ergot Derivative
Bromocriptine
Know More About This Medicine -
Click HereSummary
Bromocriptine is primarily used to treat conditions caused by high levels of prolactin, such as hormonal imbalances, infertility, or pituitary tumors. It also treats Parkinson's disease and type 2 diabetes. It can also help with menstrual irregularities.
Bromocriptine works by stimulating dopamine receptors in the brain. This suppresses the production of prolactin from the pituitary gland, improves motor control in Parkinson's disease, and helps regulate blood sugar in diabetes.
For prolactin-related conditions, 1.25-2.5 mg daily is common, with gradual adjustments. For Parkinson's disease, doses may go up to 10-40 mg daily. The medicine should be swallowed whole with water.
Common side effects include nausea, vomiting, headache, dizziness, and fatigue. Serious risks include low blood pressure, hallucinations, and heart issues.
Bromocriptine should be avoided if you are allergic to it, have uncontrolled high blood pressure, heart disease, or severe liver impairment. It is not recommended for breastfeeding mothers unless prescribed for conditions like milk oversupply. Alcohol can worsen side effects, so it is best to avoid drinking while on Bromocriptine.
Indications and Purpose
What is Bromocriptine used for?
Bromocriptine treats high prolactin levels, pituitary tumors, Parkinson’s disease, and type 2 diabetes. It also helps with menstrual irregularities, infertility, and conditions like acromegaly (excessive growth hormone).
How does Bromocriptine work?
Bromocriptine activates dopamine receptors in the brain. This suppresses prolactin production from the pituitary gland, improves motor control in Parkinson’s, and helps regulate blood sugar in diabetes.
Is Bromocriptine effective?
Yes, Bromocriptine has proven effective in managing conditions like high prolactin, Parkinson’s, and diabetes. Studies show it normalizes prolactin levels, reduces tumor size, improves motor symptoms, and lowers blood sugar.
How does one know if Bromocriptine is working?
Blood tests (prolactin levels or blood sugar), symptom improvement (e.g., regular menstruation or better motor function), and imaging (tumor size reduction) are used to evaluate its effectiveness.
Directions for Use
What is the usual dose of Bromocriptine?
The adult dose varies depending on the condition. For prolactin-related conditions, 1.25–2.5 mg daily is common, with gradual adjustments. For Parkinson’s, doses may go up to 10–40 mg daily. Pediatric doses are less common and must be determined by a doctor.
How do I take Bromocriptine?
Take Bromocriptine with food to reduce nausea. Swallow the tablet whole with water. Follow your doctor’s prescription strictly, and do not stop or change the dose without consulting them.
For how long do I take Bromocriptine?
The treatment duration depends on your condition and how you respond. Some may need long-term use, especially for chronic conditions like Parkinson’s or hormonal imbalances. Your doctor will regularly evaluate your progress.
How long does it take for Bromocriptine to start working?
For high prolactin, you may notice improvements within a few days to weeks. Diabetes and Parkinson’s symptoms may take a few weeks to months to improve. Regular monitoring helps assess progress.
How should I store Bromocriptine?
**How should I store this medicine?** **Acetaminophen:** * Keep the medicine in its original container, tightly closed, out of children's reach. * Store it at room temperature, away from light, excess heat, and moisture. * Avoid storing it in the bathroom.
Warnings and Precautions
Who should avoid taking Bromocriptine?
Avoid Bromocriptine if you are allergic to it or have uncontrolled high blood pressure, heart disease, or severe liver impairment. Pregnant women with specific conditions must consult their doctor first.
Can I take Bromocriptine with other prescription drugs?
Some drugs, like antihypertensives, antidepressants, and antipsychotics, may interact with Bromocriptine. Always share your medication list with your doctor to avoid harmful interactions.
Can I take Bromocriptine with vitamins or supplements?
Generally, vitamins are safe, but inform your doctor about any supplements, as some may interact or worsen side effects like nausea or dizziness.
Can Bromocriptine be taken safely while pregnant?
It may be used in certain cases under a doctor’s supervision. Bromocriptine is often prescribed to treat infertility before pregnancy but must be discontinued once pregnant unless advised otherwise.
Can Bromocriptine be taken safely while breastfeeding?
Bromocriptine suppresses milk production, so it is not recommended for breastfeeding mothers unless specifically prescribed for conditions like milk oversupply.
Is Bromocriptine safe for the elderly?
Elderly patients may be more sensitive to side effects like dizziness or low blood pressure. Doses may need adjustment, and they should be closely monitored by a doctor.
Is it safe to exercise while taking Bromocriptine?
Light to moderate exercise is safe and often encouraged. Avoid strenuous activities if you feel dizzy or fatigued. Always listen to your body and consult your doctor for guidance.
Is it safe to drink alcohol while taking Bromocriptine?
Alcohol can worsen side effects like dizziness or nausea, so it is best to avoid drinking while on Bromocriptine. Discuss occasional alcohol use with your doctor for personalized advice.
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