Azathioprine
Steris Healthcare Pvt Ltd ,
سٹیریس ہیلتھ کیئر پرائیویٹ لمیٹڈ
Azathioprine 50mg Tablet 10S ,
Azathioprine 50mg Tablet 10S
DRUG STATUS
Approvals
US. FDA / uk mhra / ema / pdma
Essential Medicine
WHO / India
Use in Pregnancy
Not Advised / Caution
Pharmaceutical Class
ama / pdma
Indications and Purpose
How does Azathioprine work?
Azathioprine works by suppressing the immune system, preventing the body from attacking itself in autoimmune diseases and reducing the chances of transplant rejection by limiting immune cell production.
How does one know if Azathioprine is working?
The effectiveness of azathioprine can be monitored through clinical evaluation, laboratory tests (such as blood work to monitor white blood cell count), and observing the improvement of symptoms related to the treated condition, like inflammation or organ function.
Is Azathioprine effective?
Yes, azathioprine is generally effective in preventing transplant rejection and treating autoimmune conditions by suppressing the immune system and reducing inflammation. However, its effectiveness varies from person to person.
What is Azathioprine used for?
Azathioprine is used to prevent organ rejection after transplants and treat autoimmune conditions like rheumatoid arthritis, lupus, Crohn’s disease, and ulcerative colitis by suppressing abnormal immune responses.
Directions for Use
For how long do I take Azathioprine?
The duration of azathioprine treatment depends on the condition being treated. For transplant recipients, it may be long-term to prevent rejection, while for autoimmune diseases, it can be used until disease control is achieved. Follow your doctor's advice regarding the length of treatment.
How do I take Azathioprine?
Azathioprine is taken orally, usually once a day, with or without food. It is important to follow the prescribed dosage exactly and take the medicine at the same time each day. If a dose is missed, take it as soon as remembered, but skip it if the next dose is near.
How long does it take for Azathioprine to start working?
Azathioprine may take several weeks to a few months to show full effects, especially in autoimmune disorders. Its effect on preventing transplant rejection can be seen relatively early but requires continuous monitoring.
How should I store Azathioprine?
Azathioprine should be stored at room temperature, away from moisture, heat, and light. Keep it out of the reach of children and dispose of any unused medication according to your pharmacist’s advice.
What is the usual dose of Azathioprine?
The typical starting dose for azathioprine in adults is 1 to 3 mg per kilogram of body weight per day, depending on the condition being treated. For children, the dose is usually calculated based on weight and specific health needs. The dosage may vary according to the patient's response.
Warnings and Precautions
Can Azathioprine be taken safely while breastfeeding?
Azathioprine may be passed into breast milk, and while some studies suggest it may be safe in small amounts, breastfeeding while on this medication should be discussed with a doctor to weigh potential risks.
Can Azathioprine be taken safely while pregnant?
Azathioprine should only be used during pregnancy if the benefit outweighs the risk, as it can harm the fetus. It's important to consult a healthcare provider for appropriate guidance and monitoring during pregnancy.
Can I take Azathioprine with other prescription drugs?
Azathioprine can interact with other immunosuppressive drugs, certain antibiotics, and medications that affect liver enzymes. Discuss all other prescriptions with your doctor to avoid harmful interactions.
Can I take Azathioprine with vitamins or supplements?
Azathioprine may interact with certain supplements, such as folic acid, which can reduce its effectiveness. It is important to consult your doctor about any vitamins or supplements to avoid interactions.
Does Azathioprine affect appetitie
Azathioprine can cause a loss of appetite, especially during the first few weeks of treatment. If appetite changes are severe or lead to weight loss, consult your doctor.
Does Azathioprine affect mood?
Mood changes are not common with azathioprine, but side effects like fatigue or chronic illness symptoms may impact mood. If significant mood changes occur, inform your healthcare provider.
Does Azathioprine affect sleep?
Sleep disturbances are not common with azathioprine. However, certain side effects like nausea, pain, or fever due to infections could indirectly affect sleep. Notify your doctor if sleep problems occur.
Does Azathioprine cause headaches?
Headaches are a potential side effect of azathioprine, especially if related to the underlying condition. If headaches persist or become severe, consult your doctor.
Does Azathioprine cause headaches?
Headaches are a potential side effect of azathioprine, especially if related to the underlying condition. If headaches persist or become severe, consult your doctor.
Does Azathioprine cause stomach upset?
Azathioprine can cause stomach upset, including nausea, vomiting, or loss of appetite, especially at the start of treatment. Taking the medicine with food may help reduce these side effects.
Does Azathioprine cause weight gain?
Azathioprine is not commonly associated with weight gain, but some people may experience changes in appetite or fluid retention. Notify your doctor if significant weight gain is noticed.
Does Azathioprine cause weight gain?
Azathioprine is not commonly associated with weight gain, but some people may experience changes in appetite or fluid retention. Notify your doctor if significant weight gain is noticed.
Does Azathioprine interfere with sexual function?
Azathioprine does not typically interfere with sexual function, though certain side effects like fatigue may affect libido. If sexual dysfunction occurs, discuss it with your doctor to rule out other factors.
Does Azathioprine limit driving?
Azathioprine does not usually affect the ability to drive directly. However, if you feel unwell or experience severe side effects like dizziness, avoid driving and consult a healthcare provider.
Does Azathioprine limit driving?
Azathioprine does not usually affect the ability to drive directly. However, if you feel unwell or experience severe side effects like dizziness, avoid driving and consult a healthcare provider.
Does Azathioprine make it hard to think or concentrate?
Azathioprine does not typically affect cognitive function directly. However, if you experience fatigue or other severe side effects, it might affect concentration. Report any cognitive issues to your doctor.
Does Azathioprine make people tired or drowsy?
Azathioprine generally does not cause drowsiness directly, but it can make some people feel fatigued, especially if side effects like anemia or infection occur. If you experience significant tiredness, consult your doctor.
Is Azathioprine safe for the elderly?
Azathioprine should be used with caution in elderly patients, who may be more susceptible to side effects like bone marrow suppression and liver toxicity. Close monitoring and dose adjustments may be necessary for this age group.
Is it safe to drink alcohol while taking Azathioprine?
Drinking alcohol while taking azathioprine should be avoided as it can increase the risk of liver damage and interfere with the immune-suppressing effects. Limit or avoid alcohol and consult your doctor for guidance.
Is it safe to drink alcohol while taking Azathioprine?
Drinking alcohol while taking azathioprine should be avoided as it can increase the risk of liver damage and interfere with the immune-suppressing effects. Limit or avoid alcohol and consult your doctor for guidance.
Is it safe to drink coffee or tea while taking Azathioprine?
Caffeine does not significantly affect the action of azathioprine, but excessive intake can increase side effects like anxiety or insomnia. Drink in moderation and discuss any concerns with your doctor.
Is it safe to drink coffee or tea while taking Azathioprine?
Caffeine does not significantly affect the action of azathioprine, but excessive intake can increase side effects like anxiety or insomnia. Drink in moderation and discuss any concerns with your doctor.
Is it safe to exercise while taking Azathioprine?
Moderate exercise is generally safe while taking azathioprine, but be cautious of infections or fatigue. Always discuss your exercise plans with your doctor to ensure it's safe given your condition and treatment.
Is it safe to exercise while taking Azathioprine?
Moderate exercise is generally safe while taking azathioprine, but be cautious of infections or fatigue. Always discuss your exercise plans with your doctor to ensure it's safe given your condition and treatment.
What are Azathioprine possible harms and risks?
Common side effects include nausea, vomiting, loss of appetite, and hair loss. Serious risks include bone marrow suppression, liver toxicity, and increased risk of infections and certain cancers. Regular blood tests are required to monitor for these effects.
Who should avoid taking Azathioprine?
Azathioprine should be avoided by people with a history of severe infections, liver disease, or bone marrow disorders. It's also contraindicated in pregnancy unless absolutely necessary, and special caution is needed in breastfeeding mothers.
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