Atorvastatin
Coronary Artery Disease, Hypercholesterolemia ... show more
DRUG STATUS
Approvals
US(FDA), UK(BNF)
Essential Medicine
YES
Teratogenicity
Unlisted
Pharmaceutical Class
HMG-CoA Reductase Inhibitor

Atorvastatin
Know More About This Medicine -
Click HereSummary
Atorvastatin is used to lower high cholesterol levels, raise good cholesterol, lower triglyceride levels, and reduce the risk of heart attacks, strokes, and other heart-related issues.
Atorvastatin works by blocking an enzyme in the liver that is responsible for making cholesterol. By reducing cholesterol production, it helps lower total cholesterol levels in the blood.
Atorvastatin is typically taken once a day, either before or after you eat. If taken before eating, wait at least 1 hour after taking it. If taken after eating, wait at least 2 hours after taking it.
Common side effects of Atorvastatin include stuffy nose, sore throat, diarrhea, urinary tract infection, upset stomach, nausea, muscle cramps, joint pain, trouble sleeping, and in serious cases, muscle damage and liver problems.
Atorvastatin is not recommended for pregnant or breastfeeding women. It can interact with several medications, so always inform your doctor about all the medications you're taking to avoid dangerous interactions. If you experience significant mood changes, muscle pain, or discomfort, contact your doctor immediately.
Indications and Purpose
What is Atorvastatin used for?
Atorvastatin is used to:
- Lower high cholesterol (LDL or "bad" cholesterol)
- Raise HDL (good) cholesterol
- Lower triglyceride levels
- Reduce the risk of heart attacks, strokes, and other heart-related issues.
How does Atorvastatin work?
Atorvastatin works by blocking an enzyme in the liver (HMG-CoA reductase) that is responsible for making cholesterol. By reducing cholesterol production, atorvastatin helps lower total cholesterol levels in the blood.
Is Atorvastatin effective?
Yes, atorvastatin is generally effective at lowering cholesterol levels and reducing the risk of heart disease, stroke, and heart attacks. It helps lower LDL ("bad" cholesterol), raise HDL ("good" cholesterol), and lower triglycerides.
How does one know if Atorvastatin is working?
You can know if atorvastatin is working by having blood tests that measure your cholesterol levels. Your doctor will monitor LDL and HDL levels, and triglycerides, to see if the medication is effectively lowering cholesterol. It may take a few weeks to see significant changes.
Directions for Use
How do I take Atorvastatin?
Take Atorvastatin once a day, either before or after you eat. If you take it before eating, wait at least 1 hour after taking it. If you take it after eating, wait at least 2 hours after taking it.
How long does it take for Atorvastatin to start working?
Atorvastatin can start lowering cholesterol within a few days, but it usually takes about 2 to 4 weeks to see significant effects on cholesterol levels.
How should I store Atorvastatin?
Keep at room temperature between 68° and 77°F (20° and 25°C).
Warnings and Precautions
Who should avoid taking Atorvastatin?
**Important Warnings:** * Estrogens can increase the risk of uterine cancer. Report any unusual vaginal bleeding. * Estrogens may not protect against heart disease or strokes and may increase the risk of heart attacks, strokes, breast cancer, and blood clots. Avoid using estrogens for these purposes. * If you experience fatigue, loss of appetite, upper belly pain, dark urine, or yellowing of your skin or eyes, contact your doctor immediately as these may be signs of liver problems. * If you have unexplained muscle weakness, tenderness, or pain, especially with fever or fatigue, contact your doctor right away.
Can I take Atorvastatin with other prescription drugs?
Atorvastatin can interact with several prescription medications. Some examples include:
- Certain antibiotics (like erythromycin)
- Antifungals (like itraconazole)
- Immunosuppressants (like cyclosporine)
- Blood thinners (like warfarin)
- Other cholesterol-lowering medications (like fibrates)
Always inform your doctor about all the medications you're taking to avoid dangerous interactions.
Can I take Atorvastatin with vitamins or supplements?
Atorvastatin can generally be taken with most vitamins or supplements. However, some supplements, like grapefruit juice, can interfere with the way atorvastatin works. It's also important to be cautious with supplements like fish oil, niacin, or antioxidants. Always check with your doctor or pharmacist before taking any new supplements while on atorvastatin
Can Atorvastatin be taken safely while pregnant?
Atorvastatin should not be taken by pregnant women because it can harm the baby. Women who could get pregnant should use birth control while taking atorvastatin. Studies on animals have not shown any birth defects or miscarriages at doses up to 30 times the human dose. In rats, lower baby growth and development were seen at doses 6 times the human dose.
Can Atorvastatin be taken safely while breastfeeding?
Atorvastatin is a medication used to lower cholesterol. It is not recommended for breastfeeding women because it can pass into breast milk and potentially harm the baby.
Is Atorvastatin safe for the elderly?
Atorvastatin can generally be safe for elderly people, but caution is needed. Older adults may be more prone to side effects like muscle pain or liver issues. Your doctor may adjust the dosage or monitor you more closely for side effects if you are elderly.