Amantadine
Sun Pharmaceutical Industries Ltd ,
Sun Pharmaceutical Industries Ltd
Parkitidin 129mg Tablet ER 10s ,
Parkitidin 193mg Tablet ER 10s
DRUG STATUS
Approvals
US. FDA / uk mhra / ema / pdma
Essential Medicine
WHO / India
Use in Pregnancy
Not Advised / Caution
Pharmaceutical Class
ama / pdma
Indications and Purpose
How does Amantadine work?
Amantadine works by increasing the levels of dopamine in the brain, which helps improve movement and control in conditions like Parkinson's disease. It also has antiviral properties, blocking the flu virus from spreading in the body.
How does one know if Amantadine is working?
Amantadine hydrochloride can help improve a patient's condition. If it doesn't help within a few days, or if it stops working after a few weeks, talk to your doctor. They may need to change your dose. For example, they might increase it to 300 mg each day or have you stop taking it for a while and then start again. Taking it with levodopa can also help or make the benefits more consistent.
Is Amantadine effective?
Amantadine can help prevent and treat the flu caused by influenza A viruses. It can also be used to treat Parkinson's disease. However, it's not a substitute for the flu vaccine. The flu virus can change over time, which can make amantadine less effective. For the flu, it's best to take amantadine as soon as possible after symptoms start. There's not much evidence that amantadine can help with other respiratory illnesses.
What is Amantadine used for?
Amantadine hydrochloride helps treat and prevent symptoms like shaking, stiffness, and difficulty moving in people with Parkinson's disease. It can also help control muscle spasms caused by certain medications. Additionally, amantadine can treat or prevent the flu caused by influenza A virus, especially if taken early on.
Directions for Use
For how long do I take Amantadine?
The length of time to take amantadine depends on the condition being treated. For the flu, you should take it for 1-2 days after your symptoms go away. For Parkinson's disease, it may stop working after a few months. If this happens, your doctor may increase your dose or have you stop taking it for a while. Other Parkinson's medications may also be needed.
How do I take Amantadine?
Take amantadine as prescribed, either with or without food. Follow your doctor’s instructions for the correct dosage and timing. If you miss a dose, take it as soon as possible unless it's close to the next dose. Do not double the dose. Stay hydrated, as it may cause dry mouth.
How long does it take for Amantadine to start working?
Amantadine typically starts to work within a few days to a week, though it may take longer to see full effects, especially for conditions like Parkinson’s disease. For flu prevention or treatment, it may begin working within 24 to 48 hours. Individual response times can vary. Always follow your healthcare provider’s guidance on treatment progress.
How should I store Amantadine?
Store amantadine at room temperature, away from moisture and heat. Keep it in a tightly closed container, out of reach of children. Avoid storing it in the bathroom, where humidity can affect the medication.
Warnings and Precautions
Can Amantadine be taken safely while breastfeeding?
Amantadine, a medication used to treat Parkinson's disease and influenza, passes into breast milk. It's best to avoid breastfeeding while taking amantadine, as it could potentially harm the baby.
Can Amantadine be taken safely while pregnant?
Using Amantadine during pregnancy is only recommended if the benefits to the pregnant person outweigh the potential risks to the developing baby. There is limited data on the effects of Amantadine on human pregnancies. Some reported cases suggest a possible link between Amantadine use early in pregnancy (during weeks 6-7) and certain birth defects, such as heart and limb abnormalities. However, more research is needed to confirm these findings.
Can I take Amantadine with other prescription drugs?
Be careful when taking amantadine with stimulants for the brain. Anticholinergic drugs can make the side effects of amantadine worse. Thioridazine can worsen tremors in older adults with Parkinson's disease, and triamterene/hydrochlorothiazide can raise amantadine levels in the blood. Quinine or quinidine can slow down how quickly amantadine is removed from the body. Don't take the live flu vaccine within 2 weeks before or 2 days after taking amantadine, unless a doctor says it's necessary.
Can I take Amantadine with vitamins or supplements?
**Interactions with Other Medicines:** * Taking Dyazide with amantadine can increase amantadine levels in the body. * Quinine or quinidine can reduce how quickly your body gets rid of amantadine, leading to higher levels. **Interactions with Vaccines:** * Avoid live attenuated influenza vaccine (LAIV) around amantadine use, as it could reduce its effectiveness. * Trivalent inactivated influenza vaccine can be taken with amantadine at any time.
Does Amantadine affect appetitie
Amantadine doesn't typically affect appetite, but some people may experience side effects like nausea or dry mouth that could influence appetite. If you notice significant changes, consult your healthcare provider.
Does Amantadine affect mood?
Amantadine can make mental health problems worse, such as anxiety, depression, agitation, aggression, hallucinations, paranoia, and psychosis. In some cases, it can even lead to suicide attempts, even in people who don't have a history of mental illness. However, the exact number of people who experience these side effects is not known.
Does Amantadine affect sleep?
Yes, amantadine can affect sleep. It may cause insomnia or disturbed sleep in some people, while others may feel unusually drowsy. If sleep problems occur, it's important to talk to your healthcare provider, as they may adjust the dosage or suggest ways to manage the side effect.
Does Amantadine cause headaches?
Yes, headaches are a possible side effect of amantadine. While not everyone experiences them, some individuals may develop headaches while taking the medication. If headaches are persistent or bothersome, it's important to talk to your healthcare provider.
Does Amantadine cause stomach upset?
Yes, amantadine can cause stomach upset in some people, including symptoms like nausea, vomiting, or indigestion. Taking it with food may help reduce these side effects. If stomach issues persist, consult your healthcare provider.
Does Amantadine cause weight gain?
Amantadine is not commonly associated with weight gain. However, some people may experience side effects like swelling or fluid retention, which could potentially contribute to weight changes. If you notice unexplained weight gain, it's a good idea to consult your healthcare provider..
Does Amantadine interfere with sexual function?
Amantadine hydrochloride is a medication that can sometimes lead to increased sexual urges as a side effect. If this happens, lowering the dose or stopping the medication altogether may help. However, it's important to note that the exact frequency of this side effect is unknown.
Does Amantadine limit driving?
Yes, amantadine can cause side effects like dizziness, drowsiness, or blurred vision, which may impair your ability to drive safely. It's important to assess how you feel while taking the medication before driving. If you experience any of these side effects, it's best to avoid driving and consult your healthcare provider.
Does Amantadine make it hard to think or concentrate?
At a daily dosage of 100 mg, the side effects on the nervous system were similar to those of a placebo (a substance with no active ingredient, used for comparison). However, a daily dosage of 200 mg may increase these side effects, such as trouble focusing or thinking clearly. The exact rates of these side effects are not given. If you experience these side effects, you should not do activities that need you to pay attention.
Does Amantadine make people tired or drowsy?
Yes, amantadine can cause drowsiness or fatigue in some people. It may also cause dizziness or sleep disturbances. If you experience excessive tiredness, it's important to talk to your healthcare provider to adjust the dosage or consider alternatives.
Is Amantadine safe for the elderly?
For people over 65, the dosage of amantadine hydrochloride may need to be lowered because the body doesn't get rid of it as well as it used to. It's important to watch for side effects, especially if you're taking other medications that can affect the brain or nervous system, like stimulants or anticholinergic agents. If you start to have unusual urges, like gambling or sexual thoughts, let your doctor know. They may need to lower your dose or stop the medication altogether.
What are Amantadine possible harms and risks?
Amantadine can have serious side effects, especially for people with certain health conditions. It can affect your brain and nerves, making you feel less alert, less coordinated, and less able to drive or do things that require these skills. It can also worsen mental health problems like depression and anxiety, and it can make seizures worse for people with epilepsy. Taking too much amantadine can be deadly, and it has been known to cause heart, breathing, kidney, and brain problems. If you have Parkinson's disease, suddenly stopping amantadine can cause a serious flare-up of symptoms.
Who should avoid taking Amantadine?
Amantadine is a medication that should not be taken if you are allergic to it. If you take too much of it, it can be harmful to your heart, lungs, kidneys, or brain. If you experience any of the following symptoms, seek medical attention immediately: - Mood changes - Swelling - Difficulty urinating - Shortness of breath If your condition does not improve after a few days or if it becomes worse after a few weeks, talk to your doctor. Do not take more of this medication than prescribed. If you notice an increase in gambling, sexual activity, or other intense urges, talk to your doctor. Your dose may need to be lowered or the medication may need to be stopped. Be careful if you take this medication with other medications that stimulate the central nervous system or block the effects of acetylcholine. If you have epilepsy, this medication may increase your risk of seizures. If you experience any side effects that affect your central nervous system or vision, do not drive or operate machinery. If you suspect an overdose, seek immediate medical attention.
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