Acarbose
Essar Formulations ,
Capital Pharma
Esbose 25mg Tablet ,
AC Bose 50mg Tablet
Diabetes Mellitus ,
Type 2
DRUG STATUS
Approvals
US. FDA / uk mhra / ema / pdma
Essential Medicine
WHO / India
Use in Pregnancy
Not Advised / Caution
Pharmaceutical Class
ama / pdma
Summary
Acarbose is a medication used to manage blood sugar levels in people with type 2 diabetes.
Acarbose works by blocking enzymes in your intestines that break down carbohydrates into simple sugars. This slows down the breakdown of carbohydrates, helping to prevent spikes in your blood sugar levels after meals.
Acarbose is taken by mouth with the first bite of each main meal. The starting dose is usually 25 mg three times a day, but can be increased to 50 mg three times a day if needed. The maximum dose depends on your weight.
The most common side effects of Acarbose are digestive issues like gas, diarrhea, and stomach discomfort. These usually improve over time. Serious but rare side effects include liver problems, skin reactions, swelling, intestinal blockages, and low platelet count.
Acarbose can cause hypoglycemia, especially if taken with other diabetes medications. It's also not well understood how Acarbose affects fertility or its safety during pregnancy and breastfeeding. It's important to discuss these potential risks with your healthcare provider. Certain medications and supplements, like amoxicillin, corticosteroids, and vitamin C, can interact with Acarbose.
Indications and Purpose
How does Acarbose work?
Acarbose is a medication that helps manage blood sugar levels after eating. It works by blocking enzymes in the intestines that break down carbohydrates into simple sugars. By slowing down the breakdown of carbohydrates, acarbose helps prevent spikes in blood sugar levels after meals. Acarbose does not affect the enzyme that breaks down lactose, so it does not cause lactose intolerance.
How does one know if Acarbose is working?
The benefit of Acarbose is monitored by checking blood glucose levels and HbA1c levels, and adjusting the dosage as needed.
Is Acarbose effective?
Acarbose has been shown to be effective in improving glycemic control in people with type 2 diabetes, and in reducing the risk of microvascular complications.
What is Acarbose used for?
Acarbose help people with type 2 diabetes control their blood sugar levels. They work by slowing down the breakdown of carbohydrates in food, which helps keep blood sugar levels from getting too high after meals. Acarbose should be used along with a healthy diet and exercise plan.
Directions for Use
How do I take Acarbose?
Acarbose should be taken with meals that contain carbohydrates, with the first bite of food, and patients should follow a healthy diet and avoid high-carbohydrate foods.
How long does it take for Acarbose to start working?
Acarbose starts working as soon as it is taken, and its effects can be observed within 1-2 hours after a meal. However, the full effects of the medication may not be seen for several weeks, as it takes time for the body to adjust to the new medication.
How should I dispose of Acarbose?
If you can, bring unused medicines to a drug take-back program or collection site at a pharmacy or hospital. They will dispose of the medicines properly so they don't harm people or the environment. If you can't find a take-back program, you can throw most medicines in the trash at home. But first, take them out of their original containers, mix them with something undesirable like used coffee grounds, seal the mixture in a plastic bag and throw it away.
How should I store Acarbose?
Acarbose should be stored at room temperature in a tightly closed container, protected from moisture, heat, and light. It should be used before the expiration date and disposed of properly.
What are the consequences to stopping Acarbose?
Patients should not stop taking Acarbose without consulting with their healthcare provider, as this can cause a rapid increase in blood glucose levels.
What is Acarbose’s dose and duration?
Acarbose is a medication used to treat type 2 diabetes. It is taken by mouth with the first bite of each main meal. The recommended starting dose is 25 mg three times a day. If needed, this dose can be increased to 50 mg three times a day. The maximum dose for people weighing 60 kg or less is 50 mg three times a day. The maximum dose for people weighing more than 60 kg is 100 mg three times a day.
What should I do if I miss a dose of Acarbose?
If you forget to take one or more doses: take your next dose at the normal time and in the normal amount. Do not take any more than your doctor prescribed.
Warnings and Precautions
Can Acarbose be taken safely while breastfeeding?
The safety of Acarbose during breastfeeding is unknown, and breastfeeding mothers should avoid taking the medication unless the potential benefits outweigh the potential risks.
Can Acarbose be taken safely while pregnant?
Acarbose is a Pregnancy Category B drug, but there is limited information available on its safety during pregnancy, and more research is needed.
Can Acarbose be taken safely while trying to conceive?
The effect of Acarbose on fertility is not well understood. More research is needed to confirm its safety. Patients of reproductive age should discuss potential risks and benefits with their healthcare provider.
Can I take Acarbose with other prescription drugs?
Antibiotics: Some antibiotics, such as amoxicillin, can increase the risk of hypoglycemia when taken with Acarbose.
Corticosteroids: Corticosteroids, such as prednisone, can increase blood glucose levels and reduce the effectiveness of Acarbose.
Insulin and sulfonylureas: Acarbose can increase the risk of hypoglycemia when taken with insulin or sulfonylureas, such as glipizide and glyburide.
Can I take Acarbose with vitamins or supplements?
Vitamin C: Vitamin C can decrease the effectiveness of Acarbose, as it can increase the absorption of carbohydrates in the digestive tract.
Chromium: Chromium can increase the effectiveness of Acarbose, which can increase the risk of hypoglycemia.
St. John's Wort: St. John's Wort can decrease the effectiveness of Acarbose, as it can interfere with the metabolism of the medication.
What are Acarbose possible harms and risks?
Acarbose is a medication used to lower blood sugar levels. The most common side effects are digestive issues like gas, diarrhea, and stomach discomfort. These usually improve over time. Serious but rare side effects include liver problems, skin reactions, swelling, intestinal blockages, jaundice, liver damage, low platelet count, and intestinal gas bubbles.
Who should avoid taking Acarbose?
Hypoglycemia: Acarbose can cause hypoglycemia (low blood glucose levels) in some people, especially if taken with other diabetes medications. Patients should monitor their blood glucose levels closely and report any signs of hypoglycemia to their healthcare provider.
Digestive issues: Acarbose can cause digestive issues such as bloating, flatulence, and diarrhea, especially in the first few weeks of treatment. Patients should report any digestive symptoms to their healthcare provider.
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