Tranexamic Acid
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Drug Status
Government Approvals
US(FDA)
WHO Essential Medicine
NO
Known Teratogen
NO
Pharmaceutical Class
None
Controlled Drug Substance
NO
Tranexamic Acid
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Click HereSummary
Tranexamic acid is primarily used to reduce heavy menstrual bleeding. It helps make periods lighter but doesn't stop them completely.
Tranexamic acid works by slowing down the body's process of breaking down blood clots, which helps lessen bleeding. You take it as a pill and your body gets rid of it through your kidneys.
For adults with healthy kidneys, the usual dose is three 1300mg pills per day, for a total of 3900mg daily, taken for up to five days during your period. The tablets are taken orally.
Common side effects include headaches, stuffy nose, backaches, stomach aches, and muscle or joint pain. More serious but rarer side effects include blood clots, allergic reactions, and eye problems.
Tranexamic acid shouldn't be used by women who can get pregnant and have allergies to it or who take birth control pills. It also shouldn't be used by anyone who's had blood clots. Serious side effects like blood clots in the eyes or lungs are possible and need immediate medical attention. Severe allergic reactions can also happen.
Indications and Purpose
How does one know if Tranexamic Acid is working?
The benefit of Tranexamic Acid is evaluated by monitoring the reduction in menstrual blood loss and improvement in symptoms related to heavy menstrual bleeding. Patients should report any lack of improvement or worsening of symptoms to their healthcare provider.
How does Tranexamic Acid work?
Tranexamic Acid works by inhibiting the breakdown of fibrin, a protein that helps form blood clots. It blocks the binding sites of plasminogen, preventing it from dissolving fibrin, thus stabilizing blood clots and reducing bleeding.
Is Tranexamic Acid effective?
Tranexamic Acid has been shown to effectively reduce menstrual blood loss in women with heavy menstrual bleeding. Clinical studies have demonstrated a significant reduction in menstrual blood loss compared to placebo, with improvements in social, leisure, and physical activities.
What is Tranexamic Acid?
Tranexamic Acid is used to treat heavy menstrual bleeding in women. It belongs to a class of medications called antifibrinolytics, which work by improving blood clotting. It helps reduce the amount of blood lost during menstruation but does not stop the bleeding entirely.
What is Tranexamic Acid used for?
Tranexamic Acid is indicated for the treatment of cyclic heavy menstrual bleeding in females of reproductive potential. It may also be prescribed for other conditions involving excessive bleeding, as determined by a healthcare provider.
Directions for Use
For how long do I take Tranexamic Acid?
Tranexamic Acid is typically used for up to 5 days during the menstrual cycle to treat heavy bleeding. It should not be used for more than 5 days in a row during each menstrual period.
How do I dispose of Tranexamic Acid?
If you can, bring unused medicines to a drug take-back program or collection site at a pharmacy or hospital. They will dispose of this medicine properly so they don't harm people or the environment. If you can't find a take-back program, you can throw most medicines in the trash at home. But first, take them out of their original containers, mix them with something undesirable like used coffee grounds, seal the mixture in a plastic bag and throw it away.
How do I take Tranexamic Acid?
Tranexamic Acid should be taken orally, with or without food, three times a day for up to 5 days during menstruation. There are no specific food restrictions, but it is important to follow the prescribed dosage and schedule.
How long does it take for Tranexamic Acid to start working?
Tranexamic Acid typically starts working within a few hours of taking it, as it reaches peak plasma concentration relatively quickly. The full therapeutic effect may be noticed within a day or two, depending on the condition being treated. Individual factors like metabolism and overall health can affect how quickly the medicine works. For heavy menstrual bleeding, you may notice a reduction in bleeding within the first few days of use. Always follow your healthcare provider's instructions for taking Tranexamic Acid to ensure the best results and consult them if you have any concerns about its effectiveness.
How should I store Tranexamic Acid?
Tranexamic Acid should be stored at room temperature, between 59°F to 86°F (15°C to 30°C), in its original container, tightly closed, and out of reach of children. It should be kept away from excess heat and moisture, and not stored in the bathroom.
What is the usual dose of Tranexamic Acid?
For adults, the typical dose of Tranexamic Acid is 1300 mg taken orally three times a day, for a maximum of 5 days during menstruation. For children, the dosage should be calculated based on body weight, typically 25 mg/kg per dose, but specific pediatric dosing should be confirmed with a healthcare provider.
Warnings and Precautions
Can I take Tranexamic Acid with other prescription drugs?
Tranexamic Acid should not be used with combined hormonal contraceptives due to increased risk of thrombosis. It may also interact with tissue plasminogen activators, reducing their efficacy. Patients should inform their healthcare provider of all medications they are taking to avoid interactions.
Can I take Tranexamic Acid with vitamins or supplements?
There are no well-documented confirmed interactions between Tranexamic Acid and vitamins or supplements. There is no evidence that this medicine causes nutrient depletion or requires supplementation. However, it's important to inform your healthcare provider about all medications, supplements, and conditions before starting Tranexamic Acid. This helps ensure safe use and avoids potential interactions. If you have any concerns about taking vitamins or supplements with this medication, consult your healthcare provider for personalized advice.
Can Tranexamic Acid be taken safely while breastfeeding?
Tranexamic Acid is present in breast milk at a concentration of about one hundredth of the serum concentration. The effects on the breastfed infant are unknown, so the benefits of breastfeeding should be weighed against the mother's need for the medication.
Can Tranexamic Acid be taken safely while pregnant?
Tranexamic Acid is not indicated for use in pregnant women. There is no available data on its use in pregnant women to evaluate the risk of major birth defects or miscarriage. It crosses the placenta, and its use should be avoided unless absolutely necessary.
Does Tranexamic Acid have adverse effects?
Adverse effects are unwanted or harmful effects that can occur with medication use. Tranexamic Acid may cause side effects like nausea, diarrhea, or headache, which are not very common. Rare but serious adverse effects include vision changes, blood clots, or allergic reactions, which need immediate medical attention. If you experience any new or worsening symptoms, it's important to contact your healthcare provider. They can help determine if the symptoms are related to the medication and advise on the best course of action. Always talk to your doctor before stopping any medication.
Does Tranexamic Acid have any safety warnings?
Tranexamic Acid comes with safety warnings, particularly for those with a history of blood clots, as it can increase the risk of clotting. It's important to watch for symptoms like sudden leg pain, swelling, or shortness of breath, which could indicate a clot. People with kidney problems should use it cautiously, as it can affect kidney function. If you experience any unusual symptoms, such as vision changes or severe headaches, contact your doctor immediately. Always inform your healthcare provider about your medical history and any other medications you're taking to ensure safe use.
Is it safe to drink alcohol while taking Tranexamic Acid?
Most people tolerate Tranexamic Acid well, and occasional alcoholic drinks should not affect the way this medicine works. There are no well-established interactions between Tranexamic Acid and alcohol that would interfere with the medicine's effectiveness or cause harm. However, it's always wise to consume alcohol in moderation and be aware of how your body responds. If you experience any unusual symptoms while taking the medication, consult your healthcare provider for advice. They can help determine if any adjustments are needed.
Is it safe to exercise while taking Tranexamic Acid?
Most people tolerate Tranexamic Acid well, and it should not limit your ability to exercise. There are no known symptoms caused by this medicine that would affect exercise capacity, physical strength, or endurance. However, if you experience any unusual symptoms during physical activity, such as dizziness or shortness of breath, take precautions and consult your healthcare provider. They can help determine if any adjustments to your exercise routine are needed. Always listen to your body and exercise within your comfort level.
Is it safe to stop Tranexamic Acid?
Tranexamic Acid is often used for short-term treatment of acute conditions, like heavy menstrual bleeding. Stopping it suddenly may lead to a return of symptoms, such as increased bleeding. There are no known withdrawal symptoms, but it's crucial to consult your doctor before stopping the medication. They can guide you on how to safely discontinue use and manage any returning symptoms. Never stop taking it without medical advice, as this could lead to complications depending on your condition.
Is Tranexamic Acid addictive?
Tranexamic Acid has no known potential for dependence or addiction. It is not habit-forming, and there are no behaviors or warning signs associated with physical or psychological dependence on this medication. You can use it as prescribed by your healthcare provider without concern for addiction. However, it's always important to follow your doctor's instructions and not to use the medication for longer than recommended. If you have any concerns about your medication, discuss them with your healthcare provider.
Is Tranexamic Acid safe for the elderly?
Tranexamic Acid is indicated for females of reproductive potential and is not intended for use by postmenopausal women. There are no specific dosage adjustments recommended for elderly patients unless there is evidence of renal impairment.
What are the most common side effects of Tranexamic Acid?
A side effect is an unwanted reaction that can occur with medication use. Common side effects of Tranexamic Acid include nausea, diarrhea, headache, back pain, and muscle cramps. These side effects are not very common and may be mild and temporary. It's important to note that new symptoms can occur when starting any new medicine, and they may not always be related to the medication. If you experience any new or worsening symptoms, speak to your healthcare provider before stopping the medicine. They can help determine the cause and advise on the best course of action.
Who should avoid taking Tranexamic Acid?
Tranexamic Acid is contraindicated in individuals with active thromboembolic disease, a history of thrombosis, or known hypersensitivity to the drug. It should not be used with combined hormonal contraceptives due to increased risk of thrombosis. Patients with renal impairment may require dosage adjustments.
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