Tivozanib
Renal Cell Carcinoma
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Drug Status
Government Approvals
US(FDA)
WHO Essential Medicine
NO
Known Teratogen
NO
Pharmaceutical Class
Kinase Inhibitor
Controlled Drug Substance
No
Tivozanib
Summary
Tivozanib is used to treat advanced renal cell carcinoma, a type of kidney cancer. It is particularly used when other treatments have not been successful.
Tivozanib works by blocking abnormal proteins that signal cancer cells to multiply. This helps to slow or stop the spread of cancer cells in the body.
Tivozanib is taken orally as a capsule once daily for the first 21 days of a 28-day cycle. It is important to take it at the same time each day with or without food.
Common side effects of Tivozanib include diarrhea, nausea, vomiting, fatigue, loss of appetite, weight loss, and headaches. If you experience any severe or persistent side effects, contact your doctor immediately.
Tivozanib should not be used during pregnancy or breastfeeding. It may also cause high blood pressure and bleeding problems. Men and women should use effective birth control during treatment and for one month after the final dose. Always inform your doctor about any existing health conditions and any other medications or supplements you are taking.
Indications and Purpose
How does Tivozanib work?
Tivozanib is a kinase inhibitor that works by blocking the action of abnormal proteins that signal cancer cells to multiply. By inhibiting these proteins, Tivozanib helps to slow or stop the spread of cancer cells, making it effective in treating advanced renal cell carcinoma.
Is Tivozanib effective?
Tivozanib is used to treat advanced renal cell carcinoma, particularly when other treatments have failed. It works by blocking proteins that signal cancer cells to multiply, helping to slow or stop the spread of cancer. Clinical trials and studies have shown its effectiveness in managing this type of cancer, but individual results may vary.
What is Tivozanib?
Tivozanib is used to treat advanced renal cell carcinoma, a type of kidney cancer. It works by blocking proteins that signal cancer cells to multiply, helping to slow or stop the spread of cancer. Tivozanib is taken orally in cycles and may be used when other treatments have failed.
Directions for Use
For how long do I take Tivozanib?
Tivozanib is usually taken in cycles of 28 days, with the medication taken for the first 21 days followed by a 7-day break. The cycle may be repeated as recommended by your doctor, depending on how well the medication works and the side effects experienced.
How do I take Tivozanib?
Tivozanib should be taken once daily, with or without food, for the first 21 days of a 28-day cycle. It's important to take it at the same time each day and swallow the capsules whole with a glass of water. There are no specific food restrictions, but always follow your doctor's instructions.
How should I store Tivozanib?
Store Tivozanib in its original container, tightly closed, at room temperature, away from excess heat and moisture. Keep it out of reach of children and pets. Do not store it in the bathroom. For disposal, use a medicine take-back program to ensure it is not consumed by others.
What is the usual dose of Tivozanib?
Tivozanib is typically taken as a capsule once daily for adults. It is usually taken for the first 21 days of a 28-day cycle. There is no information available for pediatric use, as it is primarily prescribed for adults with advanced renal cell carcinoma. Always follow your doctor's specific instructions regarding dosage.
Warnings and Precautions
Can Tivozanib be taken safely while breastfeeding?
Women should not breastfeed during treatment with Tivozanib and for one month after the final dose. This is to prevent any potential harm to the nursing infant. Discuss with your doctor any concerns about breastfeeding while on this medication.
Can Tivozanib be taken safely while pregnant?
Tivozanib should not be used during pregnancy as it may harm the fetus. Women should have a pregnancy test before starting treatment and use effective birth control during treatment and for one month after the final dose. Men should also use birth control to prevent pregnancy during treatment and for one month after the final dose. If pregnancy occurs, contact your doctor immediately.
Who should avoid taking Tivozanib?
Important warnings for Tivozanib include the risk of high blood pressure, bleeding problems, and potential harm to a fetus. Patients should inform their doctor of any existing health conditions, such as heart problems or liver disease. It's crucial to avoid pregnancy during treatment and for one month after the final dose. Always discuss your full medical history with your healthcare provider before starting Tivozanib.
