Thioridazine
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Drug Status
Government Approvals
US(FDA)
WHO Essential Medicine
NO
Known Teratogen
NO
Pharmaceutical Class
Phenothiazine
Controlled Drug Substance
NO
Thioridazine
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Click HereSummary
Thioridazine is used to treat symptoms of schizophrenia, particularly in individuals who haven't responded well to at least two other medications.
Thioridazine works by decreasing abnormal excitement in the brain. It belongs to a group of medications called conventional antipsychotics, which help control schizophrenia symptoms by affecting the balance of certain chemicals in the brain.
Thioridazine is taken as a tablet by mouth, usually two to four times a day. The exact dosage is determined by your doctor based on your condition and response to treatment.
Common side effects of Thioridazine include drowsiness, changes in appetite, mood changes, gastrointestinal issues like nausea and constipation, and weight gain. It can also cause sexual side effects and cognitive effects like difficulty concentrating.
Thioridazine can cause a serious irregular heartbeat potentially leading to sudden death. It should only be used if other medications have failed. Patients with heart conditions or low potassium levels should avoid it. It's also not recommended for older adults with dementia due to an increased risk of death.
Indications and Purpose
What is Thioridazine used for?
Thioridazine is indicated for the treatment of schizophrenia, a mental illness characterized by disturbed or unusual thinking, loss of interest in life, and strong or inappropriate emotions. It is prescribed for patients who have not been helped by at least two other medications or have experienced severe side effects from them.
How does Thioridazine work?
Thioridazine works by decreasing abnormal excitement in the brain. It belongs to a group of medications called conventional antipsychotics, which help control symptoms of schizophrenia by affecting the balance of certain chemicals in the brain. This action helps reduce symptoms like disturbed thinking and inappropriate emotions.
Is Thioridazine effective?
Thioridazine is used to treat symptoms of schizophrenia in individuals who have not responded well to at least two other medications. It belongs to a group of medications called conventional antipsychotics and works by decreasing abnormal excitement in the brain. Its effectiveness is based on its ability to control symptoms, although it does not cure the condition.
How does one know if Thioridazine is working?
The benefit of thioridazine is evaluated by monitoring the control of schizophrenia symptoms. Regular doctor visits and laboratory tests, including electrocardiograms, help assess the medication's effectiveness and safety. Patients should communicate any changes in symptoms or side effects to their doctor, who may adjust the dosage or treatment plan accordingly.
Directions for Use
What is the usual dose of Thioridazine?
The usual daily dose of thioridazine for adults is typically determined by the doctor based on the patient's condition and response to treatment. It is usually taken two to four times a day. For children, the dosage is also determined by the doctor and is based on the child's weight and medical condition. Always follow the doctor's prescription and guidance.
How do I take Thioridazine?
Thioridazine is taken as a tablet by mouth, usually two to four times a day, at the same times each day. Follow your doctor's instructions and prescription label carefully. There are no specific food restrictions mentioned, so you can continue your usual diet unless advised otherwise by your doctor.
For how long do I take Thioridazine?
Thioridazine is used to control symptoms of schizophrenia and is typically taken for as long as the doctor prescribes. The duration of use can vary depending on the individual's response to the medication and the severity of their condition. It is important to continue taking thioridazine even if you feel well and not to stop without consulting your doctor.
How long does it take for Thioridazine to start working?
From all available and reliable information, there is no confirmed data on this. Please consult a doctor for personalized advice.
How should I store Thioridazine?
Store thioridazine in its original container, tightly closed, at room temperature, away from excess heat and moisture. Keep it out of reach of children. Do not store it in the bathroom. Dispose of unneeded medication through a take-back program, not by flushing it down the toilet. Consult your pharmacist or local waste department for disposal options.
Warnings and Precautions
Who should avoid taking Thioridazine?
Thioridazine can cause a serious irregular heartbeat, potentially leading to sudden death. It should only be used if other medications have failed. Patients with heart conditions, low potassium, or those taking certain medications should avoid it. Older adults with dementia face increased death risk. Regular heart monitoring is essential. Discuss all medications and health conditions with your doctor before use.
Can I take Thioridazine with other prescription drugs?
Thioridazine interacts with several medications, increasing the risk of serious irregular heartbeat. These include amiodarone, cisapride, disopyramide, dofetilide, erythromycin, fluoxetine, fluvoxamine, moxifloxacin, paroxetine, pimozide, pindolol, procainamide, propranolol, quinidine, sotalol, and sparfloxacin. Patients should inform their doctor of all medications they are taking to avoid dangerous interactions.
Can I take Thioridazine with vitamins or supplements?
From all available and reliable information, there is no confirmed data on this. Please consult a doctor for personalized advice.
Can Thioridazine be taken safely while pregnant?
Thioridazine may cause problems in newborns if taken during the last months of pregnancy. Pregnant women or those planning to become pregnant should discuss the risks and benefits with their doctor. There is no strong evidence from human studies on fetal harm, but caution is advised. Always consult your doctor for personalized advice.
Can Thioridazine be taken safely while breastfeeding?
From all available and reliable information, there is no confirmed data on this. Please consult a doctor for personalized advice.
Is Thioridazine safe for the elderly?
Older adults should generally avoid taking thioridazine, as it is not as safe as other medications for treating the same conditions. Studies have shown an increased risk of death in older adults with dementia who take antipsychotic medications like thioridazine. It is important for elderly patients or their caregivers to discuss the risks and benefits with their doctor before starting this medication.
Is it safe to exercise while taking Thioridazine?
Thioridazine may cause drowsiness and affect your thinking and movements, which could limit your ability to exercise safely. If you plan to engage in physical activities, discuss this with your doctor to ensure it is safe for you. They may provide guidance on how to manage any side effects that could impact your exercise routine.
Is it safe to drink alcohol while taking Thioridazine?
Drinking alcohol while taking thioridazine can worsen the side effects of the medication, such as drowsiness and dizziness. It is important to ask your doctor about the safe use of alcohol while on this medication. To ensure safety, it is generally advised to avoid alcohol consumption while taking thioridazine.
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