Testosterone

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Drug Status

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Government Approvals

US(FDA), UK(BNF)

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WHO Essential Medicine

YES

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Known Teratogen

NO

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Pharmaceutical Class

Androgen

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Controlled Drug Substance

YES

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Drug Ingredient

Testosterone

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Summary

  • Testosterone is used to treat hypogonadism in men, a condition where the body doesn't produce enough natural testosterone due to disorders of the testicles, pituitary gland, or hypothalamus. Symptoms of low testosterone levels such as low libido, fatigue, and muscle weakness can be alleviated with this treatment.

  • Testosterone works by replacing the hormone that the body is unable to produce in sufficient quantities. It contributes to the growth and development of male sexual organs, secondary sexual characteristics like muscle mass and body hair, and helps in maintaining energy levels, mood, and overall wellbeing.

  • The usual daily dose for Testosterone in adults is 200 mg, taken orally twice daily, once in the morning and once in the evening with food. It's important to take the medication consistently with meals to ensure proper absorption and effectiveness.

  • Common side effects of Testosterone include headache, diarrhea, and increased blood pressure. Serious adverse effects can include cardiovascular events, liver disease, and mood changes. If you experience any unusual symptoms, you should inform your healthcare provider immediately.

  • Testosterone should not be used by pregnant women because of the risk of virilization of the female fetus. It's also contraindicated in patients with breast or prostate cancer, and those with known hypersensitivity to the drug. Patients with cardiovascular risk factors should be closely monitored.

Indications and Purpose

How does one know if Testosterone is working?

The benefit of testosterone is evaluated by monitoring serum testosterone concentrations and assessing the patient's response to treatment. Regular blood tests are conducted to ensure testosterone levels are within the normal range. The dosage may be adjusted based on these results and the patient's symptoms to optimize treatment effectiveness.

How does Testosterone work?

Testosterone is a hormone that contributes to the growth, development, and functioning of male sexual organs and typical male characteristics. It works by replacing the testosterone that is normally produced by the body, helping to maintain normal testosterone levels and alleviate symptoms associated with low testosterone.

Is Testosterone effective?

Testosterone is used to treat symptoms of low testosterone in men with hypogonadism, a condition where the body does not produce enough natural testosterone. It is effective in replacing testosterone that is normally produced by the body, helping to alleviate symptoms associated with low testosterone levels. Regular monitoring of testosterone levels ensures the treatment's effectiveness.

What is Testosterone?

Testosterone is used to treat symptoms of low testosterone in men with hypogonadism, a condition where the body does not produce enough natural testosterone. It works by replacing the testosterone that is normally produced by the body, helping to alleviate symptoms associated with low testosterone levels. Regular monitoring of testosterone levels ensures the treatment's effectiveness.

What is Testosterone used for?

Testosterone is indicated for the treatment of hypogonadism in men, a condition where the body does not produce enough natural testosterone. It is used for men with low testosterone levels caused by specific medical conditions, including disorders of the testicles, pituitary gland, or hypothalamus, but not for age-related low testosterone.

Directions for Use

For how long do I take Testosterone?

Testosterone is typically used as a long-term treatment for conditions associated with low testosterone levels. The duration of use depends on the individual's medical condition and response to treatment. Regular monitoring by a healthcare provider is essential to adjust the dosage and evaluate the effectiveness of the therapy.

How do I take Testosterone?

Testosterone should be taken orally with food, twice a day, once in the morning and once in the evening. It is important to take it at the same times every day. There are no specific food restrictions, but it is essential to follow your doctor's instructions regarding dosage and administration.

How should I store Testosterone?

Testosterone should be stored in its original container, tightly closed, at room temperature, away from excess heat and moisture. It should be kept out of reach of children. Unused medication should be disposed of through a take-back program, not flushed down the toilet, to prevent accidental ingestion by pets or children.

What is the usual dose of Testosterone?

For adults, the typical starting dose of testosterone is 200 mg taken orally twice daily, once in the morning and once in the evening, with food. The dose may be adjusted based on testosterone levels in the blood. Testosterone is not recommended for use in children under 18 years old due to potential effects on bone growth and development.

Warnings and Precautions

Can I take Testosterone with other prescription drugs?

Testosterone can interact with insulin, potentially affecting blood glucose levels, and with oral vitamin K antagonist anticoagulants, affecting anticoagulant activity. It may also interact with corticosteroids, leading to increased fluid retention. Patients should inform their healthcare provider of all medications they are taking to manage potential interactions effectively.

Can Testosterone be taken safely while breastfeeding?

Testosterone is not indicated for use in women, including those who are breastfeeding. There is a potential risk of harm to the nursing infant, and therefore, testosterone should not be used by breastfeeding women.

Can Testosterone be taken safely while pregnant?

Testosterone is contraindicated in pregnant women as it can cause virilization of the female fetus. There is strong evidence from animal studies that exposure to testosterone during pregnancy can result in structural impairments and hormonal changes in offspring. Women who are pregnant or may become pregnant should not use testosterone.

Is Testosterone safe for the elderly?

There is insufficient long-term safety data on the use of testosterone in geriatric patients to assess the potentially increased risk of cardiovascular disease and prostate cancer. Elderly patients treated with testosterone may be at risk for worsening signs and symptoms of benign prostatic hyperplasia (BPH). Regular monitoring by a healthcare provider is essential to ensure safe use.

Who should avoid taking Testosterone?

Testosterone can increase blood pressure, raising the risk of heart attack or stroke. It should not be used by individuals with breast or prostate cancer, or by women who are pregnant. Testosterone is contraindicated in men with age-related low testosterone. Regular monitoring of blood pressure and testosterone levels is essential during treatment.