Terbutaline
Asthma
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Drug Status
Government Approvals
UK(BNF)
WHO Essential Medicine
YES
Known Teratogen
NO
Pharmaceutical Class
None
Controlled Drug Substance
No
Terbutaline
Summary
Terbutaline is primarily used to treat conditions like asthma, chronic obstructive pulmonary disease (COPD), and bronchospasm, which are all related to difficulty in breathing. It helps in relaxing the muscles in the airways. In some cases, it's also used to delay preterm labor for a short time.
Terbutaline works by activating something called beta-2 adrenergic receptors. These receptors help to relax the smooth muscles in your airways, making it easier for you to breathe. In pregnancy, it can relax the muscles in the uterus to delay labor contractions.
For adults, the usual dose of Terbutaline is 2.5 mg to 5 mg taken three times daily. For children over 6 years, the typical dose is 2.5 mg three times daily. The maximum daily dose should not exceed 15 mg for adults and 7.5 mg for children.
Common side effects of Terbutaline include tremors, nervousness, dizziness, headache, nausea, and a fast heartbeat. Serious risks include irregular heart rhythms, chest pain, and high blood pressure. Rarely, severe allergic reactions may occur causing rash, swelling or breathing difficulty.
People with heart disease, high blood pressure, diabetes, or hyperthyroidism should use Terbutaline cautiously. Pregnant women should avoid long-term use due to potential risks to the fetus. If you have a history of seizures or irregular heartbeat, consult your doctor before using it.
Indications and Purpose
How does Terbutaline work?
Terbutaline works by activating beta-2 adrenergic receptors, which relax the smooth muscles in the airways. This helps to open up the lungs, making it easier to breathe. In pregnancy, it relaxes the uterine muscles to delay labor contractions.
Is Terbutaline effective?
Yes, terbutaline is effective in relaxing airway muscles and improving breathing in people with asthma and COPD. Studies show it significantly reduces wheezing, shortness of breath, and coughing. It is also effective in delaying labor contractions but is no longer the preferred treatment for this use.
What is Terbutaline?
Terbutaline is a bronchodilator used to treat asthma, chronic bronchitis, and emphysema by relaxing airway muscles. It is also sometimes used for preterm labor to delay childbirth. It works by stimulating beta-2 adrenergic receptors, which help open airways and make breathing easier.
Directions for Use
For how long do I take Terbutaline?
The duration of terbutaline treatment depends on your condition. For asthma or bronchitis, it is used as needed or long-term. If used for preterm labor, it is typically given for a short period under strict medical supervision.
How do I take Terbutaline?
Terbutaline tablets should be taken with or without food. If stomach upset occurs, take it with food. Drink plenty of water to stay hydrated. Avoid caffeinated drinks, as they can increase side effects like nervousness and a fast heartbeat.
How long does it take for Terbutaline to start working?
Terbutaline starts working within 30 minutes after taking a tablet and reaches peak effect in 2-3 hours. The effects typically last up to 6 hours. If used as an injection or inhaler, it works much faster—within 5 to 15 minutes.
How should I store Terbutaline?
Store terbutaline at room temperature (15-30°C), away from moisture, heat, and direct sunlight. Keep it in a tightly closed container and out of reach of children. Do not use expired medication.
What is the usual dose of Terbutaline?
For adults, the usual dose is 2.5 mg to 5 mg taken three times daily. For children over 6 years, the typical dose is 2.5 mg three times daily. The maximum daily dose should not exceed 15 mg for adults and 7.5 mg for children.
Warnings and Precautions
Can I take Terbutaline with other prescription drugs?
Terbutaline may interact with beta-blockers (like propranolol), diuretics, and antidepressants. Taking it with other stimulants or asthma medications can increase heart-related side effects. Always check with your doctor before combining it with other medications.
Can Terbutaline be taken safely while breastfeeding?
Yes, terbutaline passes into breast milk in small amounts but is generally considered safe for breastfeeding infants. However, watch for signs of irritability or fast heartbeat in your baby. Consult your doctor if any concerns arise.
Can Terbutaline be taken safely while pregnant?
Terbutaline is sometimes used to delay preterm labor, but it is not recommended for long-term use due to risks to the baby. It may cause increased heart rate and blood sugar levels in both the mother and fetus. Use only under strict medical supervision.
Is it safe to drink alcohol while taking Terbutaline?
It is not recommended to drink alcohol while taking terbutaline, as alcohol can worsen side effects like dizziness, increased heart rate, and low blood pressure. If you choose to drink, do so in moderation and watch for any unusual reactions. If symptoms worsen, avoid alcohol completely.
Is it safe to exercise while taking Terbutaline?
Yes, but with caution. Terbutaline can cause increased heart rate and muscle tremors, which may be intensified during exercise. Avoid high-intensity workouts immediately after taking the medicine. Light to moderate exercise is usually safe, but if you feel chest pain, dizziness, or excessive fatigue, stop exercising and seek medical help.
Is Terbutaline safe for the elderly?
Elderly patients may be more sensitive to terbutaline’s side effects, especially heart-related issues like palpitations and high blood pressure. Lower doses may be recommended to reduce risks. Regular monitoring is advised.
Who should avoid taking Terbutaline?
People with heart disease, high blood pressure, diabetes, or hyperthyroidism should use terbutaline cautiously. Pregnant women should avoid long-term use due to potential fetal risks. If you have a history of seizures or irregular heartbeat, consult your doctor before using it.
