Tacrolimus is used to prevent organ rejection after a transplant, which is when the body attacks a new organ. It is also used for certain autoimmune diseases, which are conditions where the immune system attacks the body's own tissues.
Tacrolimus works by suppressing the immune system, which is the body's defense system against infections. It inhibits a protein called calcineurin, which is involved in activating immune cells, helping to prevent organ rejection.
Tacrolimus is usually taken twice daily, in the morning and evening, on an empty stomach. The dose varies based on individual needs and is adjusted by the doctor. It is important to follow the doctor's instructions carefully.
Common side effects of Tacrolimus include tremors, which are involuntary shaking, headaches, and high blood pressure, which is when the force of blood against artery walls is too high. These effects vary in severity.
Tacrolimus can increase the risk of infections and certain cancers due to its immune-suppressing effects. It is not recommended for people with certain kidney problems. Always inform your doctor about your medical history before starting Tacrolimus.
Drug Status
Government Approvals
UK(BNF)
WHO Essential Medicine
YES
Known Teratogen
NO
Pharmaceutical Class
Calcineurin Inhibitor Immunosuppressant
Controlled Drug Substance
No
Drug Ingredient
tacrolimus
Summary
Tacrolimus is used to prevent organ rejection after a transplant, which is when the body attacks a new organ. It is also used for certain autoimmune diseases, which are conditions where the immune system attacks the body's own tissues.
Tacrolimus works by suppressing the immune system, which is the body's defense system against infections. It inhibits a protein called calcineurin, which is involved in activating immune cells, helping to prevent organ rejection.
Tacrolimus is usually taken twice daily, in the morning and evening, on an empty stomach. The dose varies based on individual needs and is adjusted by the doctor. It is important to follow the doctor's instructions carefully.
Common side effects of Tacrolimus include tremors, which are involuntary shaking, headaches, and high blood pressure, which is when the force of blood against artery walls is too high. These effects vary in severity.
Tacrolimus can increase the risk of infections and certain cancers due to its immune-suppressing effects. It is not recommended for people with certain kidney problems. Always inform your doctor about your medical history before starting Tacrolimus.
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