Sertraline
Post-Traumatic Stress Disorders, Depressive Disorder ... show more
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Drug Status
Government Approvals
US(FDA), UK(BNF)
WHO Essential Medicine
NO
Known Teratogen
No
Pharmaceutical Class
Serotonin Reuptake Inhibitor
Controlled Drug Substance
No
Sertraline
Summary
Sertraline is used to treat depression and anxiety disorders, which are conditions that affect mood and cause feelings of sadness or worry. It may also be prescribed for other conditions as determined by your doctor.
Sertraline works by increasing serotonin levels in the brain, which is a chemical that helps improve mood and reduce anxiety. It does this by blocking the reuptake of serotonin, allowing it to have a greater effect.
The usual starting dose of Sertraline for adults is 50 mg once daily, which can be adjusted by your doctor. It is taken orally, either in the morning or evening, with or without food.
Common side effects of Sertraline include nausea, insomnia, and dizziness, which are unwanted reactions to the medication. These effects are usually mild and affect more than 10% of users.
Sertraline can increase the risk of suicidal thoughts, especially in young people. It should not be used with MAO inhibitors, which are a type of antidepressant, due to the risk of serotonin syndrome, a serious condition.
Indications and Purpose
How does Sertraline work?
Sertraline works by blocking the reuptake of serotonin, which is a chemical in the brain that affects mood. This increases serotonin levels, helping to improve mood and reduce anxiety. Think of it like a sponge that holds more water, allowing serotonin to have a greater effect on the brain.
Is Sertraline effective?
Yes, Sertraline is effective for treating depression, anxiety, and other mood disorders. It works by increasing serotonin levels in the brain, which helps improve mood. Clinical studies show significant improvement in symptoms for many users. Always follow your doctor's advice and report any concerns about your treatment.
What is Sertraline?
Sertraline is a medication in the selective serotonin reuptake inhibitor (SSRI) class. It works by increasing serotonin levels in the brain, which helps improve mood. It's primarily used to treat depression and anxiety disorders. It may also be used for other conditions as determined by your doctor.
Directions for Use
For how long do I take Sertraline?
Sertraline is usually taken long-term for chronic conditions like depression and anxiety. The duration depends on your response and doctor's advice. Some people may need it for several months, while others may require longer treatment. Always follow your doctor's guidance and do not stop without consulting them.
How do I dispose of Sertraline?
Dispose of Sertraline by taking it to a drug take-back program or collection site at a pharmacy or hospital. If unavailable, mix the medication with an undesirable substance like used coffee grounds, seal it in a plastic bag, and throw it in the trash. This prevents harm to people and the environment.
How do I take Sertraline?
Take Sertraline once daily, either in the morning or evening, with or without food. Swallow the tablet whole; do not crush or chew it. If you miss a dose, take it as soon as you remember, unless it's close to your next dose. In that case, skip the missed dose. Do not double up on doses. Avoid alcohol while taking Sertraline, as it can increase side effects. Always follow your doctor's specific instructions regarding your dosage and any dietary restrictions.
How long does it take for Sertraline to start working?
Sertraline may start to improve symptoms within 1 to 2 weeks, but it can take 4 to 6 weeks to achieve its full effect. Individual factors like age and overall health can affect how quickly it works. Always take it as prescribed and consult your doctor if you have concerns.
How should I store Sertraline?
Store Sertraline at room temperature, away from moisture and light. Keep it in a tightly closed container. Do not store it in the bathroom, where humidity can affect it. Always keep it out of reach of children and check the expiration date regularly.
What is the usual dose of Sertraline?
The usual starting dose of Sertraline for adults is 50 mg once daily. Your doctor may adjust the dose based on your response and needs, with a maximum recommended dose of 200 mg per day. For children and the elderly, dose adjustments may be necessary. Always follow your doctor's specific dosing instructions for your health needs.
Warnings and Precautions
Can I take Sertraline with other prescription drugs?
Sertraline can interact with other medications, increasing the risk of side effects. Avoid using it with MAO inhibitors, which are a type of antidepressant, as this can cause serotonin syndrome, a serious condition. Inform your doctor about all medications you take to prevent harmful interactions.
Can Sertraline be taken safely while breastfeeding?
Sertraline is generally considered safe while breastfeeding, as only small amounts pass into breast milk. However, monitor the baby for any unusual symptoms like irritability or poor feeding. Always consult your doctor to ensure the benefits outweigh any potential risks.
Can Sertraline be taken safely while pregnant?
The safety of Sertraline during pregnancy is not fully established. Some studies suggest potential risks, but untreated depression can also harm both mother and baby. Always discuss with your doctor to weigh the benefits and risks and to create a safe treatment plan during pregnancy.
Does Sertraline have adverse effects?
Adverse effects are unwanted reactions to a medication. Common adverse effects of Sertraline include nausea, insomnia, and dizziness. These occur in more than 10% of users. Serious effects like serotonin syndrome, which is a dangerous condition with symptoms like confusion and rapid heart rate, are rare but require immediate medical attention. Always inform your doctor about any new or worsening symptoms.
Does Sertraline have any safety warnings?
Yes, Sertraline has important safety warnings. It can increase the risk of suicidal thoughts, especially in young people. Monitor for mood changes and report them to your doctor. Sertraline can also cause serotonin syndrome, which is a serious condition with symptoms like confusion and rapid heart rate. If you experience these, seek medical help immediately. Always follow your doctor's advice and report any unusual symptoms.
Is it safe to drink alcohol while taking Sertraline?
It's best to avoid alcohol while taking Sertraline. Alcohol can increase side effects like drowsiness and dizziness. It may also worsen depression or anxiety. If you choose to drink, do so in moderation and consult your doctor for personalized advice.
Is it safe to exercise while taking Sertraline?
Yes, it's safe to exercise while taking Sertraline. Exercise can improve mood and reduce anxiety. However, Sertraline can cause dizziness, so start slowly and stay hydrated. If you feel dizzy or lightheaded, stop exercising and rest. Consult your doctor if you have concerns about your exercise routine.
Is it safe to stop Sertraline?
Stopping Sertraline suddenly can cause withdrawal symptoms like dizziness and irritability. It's usually used long-term for conditions like depression and anxiety. Always consult your doctor before stopping. They may suggest gradually reducing your dose to minimize withdrawal effects and ensure your condition remains stable.
Is Sertraline addictive?
No, Sertraline is not considered addictive or habit-forming. It does not cause cravings or withdrawal symptoms typical of addictive substances. However, stopping Sertraline suddenly can lead to withdrawal symptoms like dizziness and irritability. To avoid these, your doctor may gradually reduce your dose when it's time to stop the medication.
Is Sertraline safe for the elderly?
Elderly individuals are more vulnerable to medication side effects due to age-related changes in the body. Sertraline is generally safe for the elderly, but they may experience more dizziness or drowsiness. Close monitoring by a doctor is important to adjust doses and manage any side effects.
What are the most common side effects of Sertraline?
Side effects are unwanted reactions to a medication. Common side effects of Sertraline include nausea, insomnia, and dizziness, affecting more than 10% of users. These effects vary among individuals and may be temporary or unrelated to the medication. If you experience new symptoms, consult your doctor before stopping the medication.
Who should avoid taking Sertraline?
Do not use Sertraline if you are allergic to it or its ingredients. It's contraindicated with MAO inhibitors, which are a type of antidepressant, due to the risk of serotonin syndrome, a serious condition. Caution is needed if you have liver disease or a history of seizures. Always consult your doctor about your medical history before starting Sertraline.
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