Satralizumab
NA
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Drug Status
Government Approvals
US(FDA)
WHO Essential Medicine
NO
Known Teratogen
No
Pharmaceutical Class
None
Controlled Drug Substance
No
Summary
Satralizumab is used to treat neuromyelitis optica spectrum disorder, which is a condition affecting the optic nerves and spinal cord. It helps reduce inflammation and prevent attacks by targeting a specific protein involved in the immune response.
Satralizumab works by targeting and blocking a protein called interleukin-6, which plays a role in the immune response. By blocking this protein, satralizumab helps reduce inflammation and prevent attacks in neuromyelitis optica spectrum disorder.
Satralizumab is usually given as an injection under the skin. The starting dose for adults is 120 mg, typically administered once every two weeks for the first three doses, then once every four weeks.
Common side effects of satralizumab include injection site reactions, such as redness or swelling, and upper respiratory infections. These effects vary from person to person.
Satralizumab can increase the risk of infections, as it affects the immune system. If you experience symptoms like fever or persistent cough, contact your doctor. Do not use satralizumab if you're allergic to it or its ingredients.
Indications and Purpose
How does satralizumab work?
Satralizumab works by targeting and blocking a protein called interleukin-6, which plays a role in the immune response. By blocking this protein, satralizumab helps reduce inflammation and prevent attacks in neuromyelitis optica spectrum disorder. Think of it like turning down the volume on an overactive immune system, helping to calm it down.
Is satralizumab effective?
Satralizumab is effective in treating neuromyelitis optica spectrum disorder, which is a condition that affects the optic nerves and spinal cord. Clinical studies show it reduces the frequency of relapses in patients. This medication works by targeting and blocking a specific protein involved in the immune response, helping to reduce inflammation and prevent attacks.
What is satralizumab?
Satralizumab is a medication used to treat neuromyelitis optica spectrum disorder, which is a condition affecting the optic nerves and spinal cord. It belongs to a class of drugs called monoclonal antibodies, which work by targeting and blocking a specific protein involved in the immune response. This helps reduce inflammation and prevent attacks.
Directions for Use
For how long do I take satralizumab?
Satralizumab is usually a long-term medication for managing neuromyelitis optica spectrum disorder. You'll typically take it as prescribed by your doctor for as long as it effectively controls your symptoms. Stopping this medication without medical advice could cause your condition to worsen. Always talk with your doctor before changing or stopping your treatment.
How do I dispose of satralizumab?
To dispose of satralizumab, bring unused medicine to a drug take-back program or collection site at a pharmacy or hospital. If you can't find a take-back program, you can throw it in the trash at home. First, take it out of its original container, mix it with something undesirable like used coffee grounds, seal it in a plastic bag, and throw it away.
How do I take satralizumab?
Satralizumab is usually given as an injection under the skin. Your doctor will provide specific instructions on how to administer it. The frequency of the dose is typically every four weeks after the initial loading doses. It's important to follow your doctor's instructions carefully. If you miss a dose, contact your healthcare provider for advice. Do not double up on doses to make up for a missed one.
How long does it take for satralizumab to start working?
Satralizumab may start to work within a few weeks, but it can take several months to achieve its full therapeutic effect. The time it takes to work can vary based on individual factors like your overall health and how your body responds to the medication. Follow your doctor's instructions for the best results.
How should I store satralizumab?
Store satralizumab in the refrigerator between 36°F to 46°F. Keep it in its original packaging to protect it from light. Do not freeze it. If needed, satralizumab can be kept at room temperature for up to 8 days. Always check the expiration date and properly dispose of any unused or expired medication.
What is the usual dose of satralizumab?
The usual starting dose of satralizumab for adults is an injection of 120 mg under the skin. It's typically given once every two weeks for the first three doses, then once every four weeks. Your doctor will provide specific dosing instructions based on your health needs. Always follow your doctor's guidance for the best results.
Warnings and Precautions
Can I take satralizumab with other prescription drugs?
Satralizumab may interact with other medications that affect the immune system, increasing the risk of infections. It's important to inform your doctor about all the medications you're taking, including over-the-counter drugs and supplements. Your doctor can help manage any potential interactions and adjust your treatment plan as needed.
Can satralizumab be taken safely while breastfeeding?
The safety of satralizumab while breastfeeding is not well-established. It's unclear if the medication passes into breast milk. Discuss with your doctor if you're breastfeeding or planning to breastfeed. They can help weigh the benefits and risks and decide the best course of action for your health and your baby's safety.
Can satralizumab be taken safely while pregnant?
The safety of satralizumab during pregnancy is not well-established. Limited data is available, so it's important to discuss with your doctor if you're pregnant or planning to become pregnant. They can help weigh the benefits and risks and decide the best course of action for your health and your baby's safety.
Does satralizumab have adverse effects?
Adverse effects are unwanted reactions to a medication. Common adverse effects of satralizumab include injection site reactions and upper respiratory infections. Serious effects, though rare, can include severe infections. If you notice any new or worsening symptoms, contact your doctor immediately. They can help determine if these symptoms are related to satralizumab and advise on the best course of action.
Does satralizumab have any safety warnings?
Yes, satralizumab has important safety warnings. It can increase the risk of infections, as it affects the immune system. If you experience symptoms like fever, chills, or persistent cough, contact your doctor. Not adhering to these warnings can lead to serious health issues. Always follow your doctor's advice and report any unusual symptoms.
Is it safe to drink alcohol while taking satralizumab?
It's best to avoid alcohol while taking satralizumab. Alcohol can weaken your immune system, which may increase the risk of infections. If you choose to drink, do so in moderation and watch for any unusual symptoms. Talk with your doctor about alcohol use while taking satralizumab for personalized advice.
Is it safe to exercise while taking satralizumab?
You can exercise while taking satralizumab, but keep a few things in mind. This medication can weaken your immune system, so avoid strenuous activities if you're feeling unwell. Stay hydrated and watch for signs of fatigue or dizziness. If you notice these symptoms, slow down or stop exercising and rest. Consult your doctor if you have concerns.
Is it safe to stop satralizumab?
Stopping satralizumab suddenly can lead to a return of symptoms it was managing. It's used for long-term treatment of conditions like neuromyelitis optica spectrum disorder. Always talk with your doctor before stopping satralizumab. They might suggest a gradual reduction or an alternative treatment to keep your condition under control.
Is satralizumab addictive?
Satralizumab is not addictive or habit-forming. This medication doesn't cause dependency or withdrawal symptoms when you stop taking it. It works by affecting the immune system to reduce inflammation, not by affecting brain chemistry. You won't experience cravings for this medication or feel compelled to take more than prescribed.
Is satralizumab safe for the elderly?
The elderly may be more vulnerable to the side effects of satralizumab, as they often have weaker immune systems. Satralizumab can increase the risk of infections, which may be more severe in older adults. It's important for elderly patients to be closely monitored by their healthcare provider while taking this medication.
What are the most common side effects of satralizumab?
Side effects are unwanted reactions that can happen when taking a medication. Common side effects of satralizumab include injection site reactions, such as redness or swelling, and upper respiratory infections. These effects vary from person to person. If you notice new symptoms after starting satralizumab, they might be temporary or unrelated to the medication. Talk with your doctor before stopping any medication.
Who should avoid taking satralizumab?
Don't use satralizumab if you're allergic to it or its ingredients. Serious allergic reactions require immediate medical help. Caution is needed if you have an active infection, as satralizumab can weaken your immune system. Always consult your doctor about any health concerns before starting this medication.
