Sarecycline
Acne Vulgaris
Drug Status
Government Approvals
US(FDA)
WHO Essential Medicine
NO
Known Teratogen
No
Pharmaceutical Class
Tetracycline-class Drug
Controlled Drug Substance
No

Sarecycline
Summary
Sarecycline is an antibiotic used to treat moderate to severe acne vulgaris in individuals aged 9 years and older. It is not effective against viral infections like colds or flu.
Sarecycline works by binding to the 30S ribosomal subunit of bacteria. This inhibits protein synthesis and bacterial growth, reducing the number of bacteria in the pores and decreasing the production of a natural oily substance that contributes to acne.
Sarecycline is taken once daily with or without food. The dose is based on body weight: 60 mg for those weighing 33-54 kg, 100 mg for 55-84 kg, and 150 mg for 85-136 kg.
The most frequently reported side effect of Sarecycline is nausea, occurring in about 3.1% of users. Serious adverse effects include severe headaches, blurred vision, and intracranial hypertension.
Sarecycline should not be used during pregnancy or by children under 8 years, as it can cause fetal harm and permanent tooth discoloration. It may also cause photosensitivity, so avoid unnecessary sun exposure. Sarecycline is contraindicated in individuals with hypersensitivity to tetracyclines.
Indications and Purpose
How does Sarecycline work?
Sarecycline works by inhibiting the growth of bacteria that cause acne. It belongs to the tetracycline class of antibiotics, which block protein production in bacteria, stopping their growth. This reduces inflammation and the number of acne lesions, leading to clearer skin.
Is Sarecycline effective?
Sarecycline is effective in treating moderate to severe acne. It works by reducing inflammation and bacteria on the skin. Clinical studies show significant improvement in acne symptoms among people using Sarecycline. Always follow your doctor's instructions for the best results.
What is Sarecycline?
Sarecycline is an antibiotic used to treat moderate to severe acne. It belongs to the tetracycline class of antibiotics, which work by reducing bacteria and inflammation on the skin. Sarecycline is specifically designed to target acne-causing bacteria, making it effective for treating acne.
Directions for Use
For how long do I take Sarecycline?
Sarecycline is usually prescribed for a specific duration to treat acne, often several weeks to months. Your doctor will determine the appropriate length of treatment based on your condition and response to the medication. Always follow your doctor's instructions and complete the full course.
How do I dispose of Sarecycline?
Bring unused Sarecycline to a drug take-back program or collection site at a pharmacy or hospital. If unavailable, mix the medication with something undesirable like used coffee grounds, seal it in a plastic bag, and throw it away. This prevents harm to people and the environment.
How do I take Sarecycline?
Take Sarecycline once daily, preferably at the same time each day. You can take it with or without food. Do not crush or chew the tablet. If you miss a dose, take it as soon as you remember unless it's almost time for your next dose. In that case, skip the missed dose and continue with your regular schedule. Do not take two doses at once. Always follow your doctor's specific instructions.
How long does it take for Sarecycline to start working?
Sarecycline may start to improve acne symptoms within a few weeks, but full benefits might take several months. Individual response times can vary based on factors like the severity of acne and overall health. Follow your doctor's instructions for the best results.
How should I store Sarecycline?
Store Sarecycline at room temperature, away from moisture and light. Keep it in a tightly closed container. Do not store it in humid places like bathrooms. Always keep it out of reach of children. Check the expiration date regularly and dispose of any unused or expired medication properly.
What is the usual dose of Sarecycline?
The usual starting dose of Sarecycline for adults is 60 mg once daily. Your doctor may adjust your dose based on your response to the medication. Always follow your doctor's specific dosing instructions for your personal health needs. There are no specific dose adjustments for children or the elderly, but your doctor will monitor your treatment closely.
Warnings and Precautions
Can I take Sarecycline with other prescription drugs?
Sarecycline can interact with other medications, such as blood thinners and certain antacids, which may increase the risk of side effects or reduce effectiveness. Always inform your doctor about all medications you're taking to avoid potential interactions and ensure safe treatment.
Can Sarecycline be taken safely while breastfeeding?
Sarecycline is not recommended while breastfeeding. It may pass into breast milk and affect the baby's bone and tooth development. If you're breastfeeding and need acne treatment, talk with your doctor about safer medication options.
Can Sarecycline be taken safely while pregnant?
Sarecycline is not recommended during pregnancy. It may harm the developing baby, particularly affecting bone and tooth development. If you're pregnant or planning to become pregnant, talk with your doctor about safer alternatives for managing your condition.
Does Sarecycline have adverse effects?
Adverse effects are unwanted reactions to a medication. Common adverse effects of Sarecycline include nausea and headache. These effects are usually mild. Serious side effects are rare but can include severe skin reactions. If you notice any new or worsening symptoms, contact your doctor immediately.
Does Sarecycline have any safety warnings?
Sarecycline has important safety warnings. It can cause photosensitivity, which means your skin may become more sensitive to sunlight. Use sunscreen and wear protective clothing when outdoors. If you experience severe skin reactions, stop taking the medication and seek medical help. Always follow your doctor's advice and report any unusual symptoms.
Is it safe to drink alcohol while taking Sarecycline?
It's best to avoid alcohol while taking Sarecycline. Alcohol can increase the risk of side effects like dizziness and stomach upset. If you choose to drink, do so in moderation and watch for any unusual symptoms. Talk with your doctor about alcohol use while taking Sarecycline.
Is it safe to exercise while taking Sarecycline?
You can exercise while taking Sarecycline. This medication doesn't typically limit exercise capacity. However, if you experience dizziness or unusual fatigue, slow down or stop exercising and rest. Always stay hydrated and talk with your doctor if you have concerns.
Is it safe to stop Sarecycline?
Sarecycline is usually prescribed for a specific duration to treat acne. Stopping it early may result in the return of acne symptoms. Always follow your doctor's instructions regarding the duration of treatment. If you have concerns about stopping the medication, discuss them with your doctor.
Is Sarecycline addictive?
Sarecycline is not addictive or habit-forming. This medication doesn't cause dependency or withdrawal symptoms when you stop taking it. If you have concerns about medication dependence, you can feel confident that Sarecycline doesn't carry this risk while managing your health condition.
Is Sarecycline safe for the elderly?
The elderly may be more sensitive to the side effects of Sarecycline, such as dizziness or stomach upset. It's important for older adults to be monitored closely by their doctor while taking this medication. Always follow your doctor's advice and report any unusual symptoms.
What are the most common side effects of Sarecycline?
Side effects are unwanted reactions to a medication. Common side effects of Sarecycline include nausea and headache. These effects are usually mild and may go away on their own. If you notice new symptoms after starting Sarecycline, they might be temporary or unrelated to the medication. Talk with your doctor before stopping any medication.
Who should avoid taking Sarecycline?
Do not take Sarecycline if you're allergic to it or its ingredients. It's not recommended for use in children under 9 years old due to the risk of tooth discoloration. Pregnant or breastfeeding women should avoid it, as it may harm the baby. Always consult your doctor about these concerns.