Paroxetine
Post-Traumatic Stress Disorders, Depressive Disorder ... show more
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Drug Status
Government Approvals
US(FDA), UK(BNF)
WHO Essential Medicine
NO
Known Teratogen
NO
Pharmaceutical Class
Serotonin Reuptake Inhibitor
Controlled Drug Substance
No
Paroxetine
Summary
Paroxetine is used to treat depression and anxiety disorders, which are conditions that affect mood and cause feelings of sadness or worry. It is also used for obsessive-compulsive disorder, which involves unwanted thoughts and repetitive behaviors, and post-traumatic stress disorder, which is a condition triggered by a traumatic event.
Paroxetine works by increasing serotonin levels in the brain, which is a chemical that helps improve mood. It blocks the reuptake of serotonin, which means it prevents the brain from absorbing it too quickly, allowing more serotonin to be available to improve mood and reduce anxiety.
Paroxetine is usually taken as a tablet once daily, often in the morning. The starting dose for adults is typically 20 mg per day, but your doctor may adjust it based on your needs. It's important to swallow the tablet whole and not to crush it.
Common side effects of Paroxetine include nausea, which is an upset stomach, dizziness, which is feeling lightheaded, and drowsiness, which is feeling sleepy. These effects are usually mild and may improve as your body adjusts to the medication.
Paroxetine can increase the risk of suicidal thoughts, especially in young adults. It should not be taken with MAO inhibitors, which are another type of antidepressant, due to the risk of serotonin syndrome, a serious condition. Always consult your doctor about your medical history before starting Paroxetine.
Indications and Purpose
How does Paroxetine work?
Paroxetine works by blocking the reuptake of serotonin, which is a chemical in the brain that affects mood. This increases serotonin levels, helping improve mood and reduce anxiety. Think of it like a sponge that holds onto more water, keeping serotonin available for longer. This helps treat depression and anxiety disorders.
Is Paroxetine effective?
Yes, Paroxetine is effective for treating depression, anxiety disorders, and other mental health conditions. It works by increasing serotonin levels in the brain, which helps improve mood. Clinical studies show significant improvement in symptoms for many users. Always follow your doctor's instructions for the best results.
What is Paroxetine?
Paroxetine is a medication in the selective serotonin reuptake inhibitor (SSRI) class. It works by increasing serotonin levels in the brain, which helps improve mood. It's primarily used to treat depression and anxiety disorders. Paroxetine can also be used for other conditions like obsessive-compulsive disorder and post-traumatic stress disorder.
Directions for Use
For how long do I take Paroxetine?
Paroxetine is usually taken long-term for chronic conditions like depression and anxiety. The duration depends on your response and any side effects. Your doctor will guide you on how long to continue treatment. Never stop taking Paroxetine without consulting your doctor, as it can cause withdrawal symptoms.
How do I dispose of Paroxetine?
Dispose of Paroxetine by taking it to a drug take-back program or collection site at a pharmacy or hospital. If that's not possible, mix it with something undesirable like used coffee grounds, seal it in a plastic bag, and throw it away. This helps prevent harm to people and the environment.
How do I take Paroxetine?
Take Paroxetine once daily, usually in the morning, with or without food. Swallow the tablet whole; do not crush it. If you miss a dose, take it as soon as you remember unless it's close to your next dose. In that case, skip the missed dose. Do not double up on doses. Avoid alcohol while taking Paroxetine, as it can increase side effects. Always follow your doctor's specific instructions regarding your medication.
How long does it take for Paroxetine to start working?
Paroxetine may start working within a few days, but it can take several weeks to achieve its full effect. Individual factors like age and overall health can affect how quickly you notice improvements. Be patient and continue taking it as prescribed. Regular check-ups with your doctor will help monitor your progress.
How should I store Paroxetine?
Store Paroxetine at room temperature, away from moisture and light. Keep it in a tightly closed container. Do not store it in the bathroom, where humidity can affect it. Always keep it out of reach of children and pets. Check the expiration date regularly and dispose of any expired medication properly.
What is the usual dose of Paroxetine?
The usual starting dose of Paroxetine for adults is 20 mg once daily, usually in the morning. Your doctor may adjust your dose based on your response and needs. The maximum recommended dose is 50 mg per day. For elderly patients or those with liver problems, a lower starting dose may be recommended. Always follow your doctor's specific dosing instructions.
Warnings and Precautions
Can I take Paroxetine with other prescription drugs?
Paroxetine can interact with other medications, increasing the risk of side effects. Combining it with MAO inhibitors, which are another type of antidepressant, can cause serotonin syndrome, a serious condition. It can also interact with blood thinners, increasing bleeding risk. Always inform your doctor about all medications you take to avoid interactions.
Can Paroxetine be taken safely while breastfeeding?
Paroxetine is excreted into breast milk, but it's generally considered safe for breastfeeding. However, monitor your baby for any unusual symptoms, like irritability or poor feeding. Always discuss with your doctor before taking Paroxetine while breastfeeding to ensure it's the best option for you and your baby.
Can Paroxetine be taken safely while pregnant?
Paroxetine is not recommended during pregnancy, especially in the first trimester, due to the risk of birth defects. Limited evidence makes it hard to provide definitive advice. If you're pregnant or planning to become pregnant, talk with your doctor about safer treatment options.
Does Paroxetine have adverse effects?
Adverse effects are unwanted reactions to a medication. Common adverse effects of Paroxetine include nausea, dizziness, and drowsiness. Serious effects can include serotonin syndrome and increased suicidal thoughts. If you notice any new or worsening symptoms, contact your doctor immediately. They can help determine if these are related to Paroxetine and adjust your treatment if necessary.
Does Paroxetine have any safety warnings?
Yes, Paroxetine has important safety warnings. It can increase the risk of suicidal thoughts, especially in young adults. It may also cause serotonin syndrome, which is a potentially life-threatening condition. Symptoms include confusion, rapid heart rate, and high blood pressure. If you experience these, seek medical help immediately. Always follow your doctor's advice and report any unusual symptoms.
Is it safe to drink alcohol while taking Paroxetine?
It's best to avoid alcohol while taking Paroxetine. Alcohol can increase side effects like dizziness and drowsiness. It may also worsen depression symptoms. If you choose to drink, do so in moderation and be aware of how it affects you. Talk with your doctor for personalized advice.
Is it safe to exercise while taking Paroxetine?
Yes, it's safe to exercise while taking Paroxetine. Regular physical activity can improve mood and overall well-being. However, Paroxetine can cause dizziness, so start with light exercises and see how your body responds. If you feel dizzy or lightheaded, stop and rest. Always consult your doctor before starting a new exercise routine.
Is it safe to stop Paroxetine?
It's not safe to stop Paroxetine suddenly due to withdrawal symptoms like dizziness and irritability. These symptoms can be uncomfortable and may last for several weeks. Always talk to your doctor before stopping Paroxetine. They will guide you on how to gradually reduce your dose to minimize withdrawal effects.
Is Paroxetine addictive?
Paroxetine is not considered addictive, but it can cause withdrawal symptoms if stopped suddenly. These symptoms include dizziness, irritability, and sleep disturbances. To avoid withdrawal, your doctor will likely recommend gradually reducing your dose when it's time to stop. Always follow your doctor's instructions when discontinuing Paroxetine.
Is Paroxetine safe for the elderly?
Elderly individuals are more vulnerable to side effects from Paroxetine, such as dizziness and drowsiness, which can increase the risk of falls. It's generally safe but requires careful monitoring. Doctors may prescribe a lower dose to minimize risks. Regular check-ups are important to ensure the medication is working safely.
What are the most common side effects of Paroxetine?
Side effects are unwanted reactions to a medication. Common side effects of Paroxetine include nausea, dizziness, and drowsiness. These occur in more than 10% of users and are usually mild. If you experience new symptoms after starting Paroxetine, they might be temporary or unrelated. Talk with your doctor before stopping the medication.
Who should avoid taking Paroxetine?
Do not take Paroxetine if you're allergic to it or its ingredients. It's also contraindicated with MAO inhibitors, which are another type of antidepressant, due to the risk of serotonin syndrome. Caution is needed for those with liver problems or a history of seizures. Always consult your doctor about your medical history before starting Paroxetine.
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