Oxymorphone
Pain
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Drug Status
Government Approvals
US(FDA)
WHO Essential Medicine
NO
Known Teratogen
No
Pharmaceutical Class
Opioid Agonist
Controlled Drug Substance
No
Oxymorphone
Summary
Oxymorphone is used to manage severe acute and chronic pain in patients who require an opioid analgesic and cannot be treated with other pain medications. It's used when the pain is severe enough to need continuous opioid treatment.
Oxymorphone works by binding to opioid receptors in the brain and spinal cord. This changes the perception of pain and the emotional response to it, providing pain relief. However, it also carries risks of side effects and addiction.
For adults, the usual dose of Oxymorphone immediate-release tablets is 10 to 20 mg every 4 to 6 hours as needed for pain. It's not recommended for children. Always follow your doctor's advice for dosing.
Common side effects of Oxymorphone include nausea, vomiting, constipation, dizziness, and drowsiness. Serious adverse effects can include respiratory depression and addiction.
Key warnings for Oxymorphone include the risk of addiction, respiratory depression, and interactions with alcohol and CNS depressants. It's contraindicated in cases of severe asthma, respiratory depression, and gastrointestinal obstruction. Always consult a healthcare provider before use.
Indications and Purpose
How does Oxymorphone work?
Oxymorphone works by binding to opioid receptors in the brain and spinal cord, altering the perception of pain and emotional response to it. This action provides pain relief but also carries risks of side effects and addiction.
Is Oxymorphone effective?
Oxymorphone is an opioid analgesic that effectively relieves severe pain by altering the body's response to pain. Clinical trials have demonstrated its efficacy in managing acute and chronic pain when other treatments are inadequate.
What is Oxymorphone?
Oxymorphone is an opioid analgesic used to manage severe pain when other treatments are inadequate. It works by altering the body's response to pain, providing relief. However, it carries risks of addiction and respiratory depression, so it should be used under medical supervision.
Directions for Use
For how long do I take Oxymorphone?
Oxymorphone is typically used for short-term management of acute pain. The duration of use depends on the individual's condition and response to treatment. Long-term use is generally avoided due to the risk of addiction and other side effects.
How do I take Oxymorphone?
Take oxymorphone on an empty stomach, at least one hour before or two hours after eating. Avoid alcohol and consult your healthcare provider about any other food restrictions or interactions with your medication.
How long does it take for Oxymorphone to start working?
Oxymorphone typically begins to relieve pain within 30 minutes to an hour after taking the immediate-release form. The onset may vary based on individual factors and the specific formulation used.
How should I store Oxymorphone?
Store oxymorphone in a tightly closed container at room temperature, away from heat and moisture. Keep it out of reach of children and in a secure location to prevent misuse. Dispose of unused medication through a take-back program or by flushing it down the toilet.
What is the usual dose of Oxymorphone?
For adults, the usual dose of oxymorphone immediate-release tablets is 10 to 20 mg every 4 to 6 hours as needed for pain. For children, safety and effectiveness have not been established, so it is not recommended. Always follow your doctor's advice for dosing.
Warnings and Precautions
Can I take Oxymorphone with other prescription drugs?
Significant interactions include those with benzodiazepines, other CNS depressants, and alcohol, which can increase the risk of respiratory depression and sedation. Always inform your healthcare provider of all medications and supplements you are taking.
Can Oxymorphone be taken safely while breastfeeding?
Oxymorphone passes into breast milk and may harm a nursing infant. Monitor infants for increased sleepiness, breathing difficulties, or limpness. Consult your healthcare provider before using oxymorphone while breastfeeding.
Can Oxymorphone be taken safely while pregnant?
Using oxymorphone during pregnancy can cause neonatal opioid withdrawal syndrome, which may be life-threatening. There is limited data on fetal harm, but opioids can affect fetal development. Consult your healthcare provider for personalized advice.
Is it safe to drink alcohol while taking Oxymorphone?
Drinking alcohol while taking oxymorphone is dangerous and can lead to serious, life-threatening side effects. Alcohol can increase the risk of respiratory depression, sedation, coma, and even death. It is crucial to avoid alcohol entirely while on this medication.
Is it safe to exercise while taking Oxymorphone?
Oxymorphone can cause dizziness, drowsiness, and fatigue, which may limit your ability to exercise safely. It's important to understand how the medication affects you before engaging in physical activities. Consult your doctor for personalized advice.
Is Oxymorphone safe for the elderly?
Elderly patients should use oxymorphone with caution due to increased risk of respiratory depression and other side effects. Start with the lowest effective dose and monitor closely for adverse reactions. Consult a healthcare provider for personalized advice.
Who should avoid taking Oxymorphone?
Key warnings for oxymorphone include the risk of addiction, respiratory depression, and interactions with alcohol and CNS depressants. Contraindications include severe asthma, respiratory depression, and gastrointestinal obstruction. Always consult a healthcare provider before use.
