Oxacillin
Cellulitis , Sepsis ... show more
Drug Status
Government Approvals
US(FDA)
WHO Essential Medicine
NO
Known Teratogen
No
Pharmaceutical Class
Penicillin-class Antibacterial
Controlled Drug Substance
No
Summary
Oxacillin is used to treat bacterial infections, particularly those caused by penicillinase-producing staphylococci, which are bacteria that produce an enzyme breaking down penicillin. It's effective for skin, bone, and respiratory infections, especially when other penicillins are not effective due to bacterial resistance.
Oxacillin works by inhibiting the synthesis of bacterial cell walls, which are essential for their survival. It targets penicillinase-producing staphylococci, effectively killing the bacteria and helping to clear the infection. This makes it useful for treating resistant bacterial infections.
The usual adult dose of oxacillin is 250 mg to 500 mg every 4 to 6 hours, depending on the infection's severity. It can be taken orally or by injection. For children, the dose is based on body weight and should be determined by a doctor.
Common adverse effects of oxacillin include nausea, vomiting, and diarrhea, which are usually mild. Serious adverse effects, like severe allergic reactions, are rare but require immediate medical attention. If you notice any new or worsening symptoms, contact your doctor.
Oxacillin can cause allergic reactions, especially in people allergic to penicillin, which is a type of antibiotic. Symptoms include rash, itching, or difficulty breathing, requiring immediate medical attention. Always inform your doctor of any allergies and follow their guidance closely.
Indications and Purpose
How does oxacillin work?
Oxacillin works by inhibiting the synthesis of bacterial cell walls, which are essential for their survival. It targets penicillinase-producing staphylococci, which are bacteria that produce an enzyme breaking down penicillin. By blocking this enzyme, oxacillin effectively kills the bacteria, helping to clear the infection. This makes it useful for treating resistant bacterial infections.
Is oxacillin effective?
Oxacillin is effective in treating bacterial infections, particularly those caused by penicillinase-producing staphylococci. It works by inhibiting the growth of bacteria, helping to clear the infection. Clinical evidence supports its effectiveness in treating these types of infections. Always follow your doctor's instructions to ensure the best outcomes.
What is oxacillin?
Oxacillin is an antibiotic in the penicillin class. It works by killing bacteria, making it effective for treating infections caused by penicillinase-producing staphylococci. It's used to treat various bacterial infections, including skin, bone, and respiratory infections. Oxacillin is often used when other penicillins are not effective due to bacterial resistance.
Directions for Use
For how long do I take oxacillin?
Oxacillin is usually prescribed for short-term use to treat acute infections. The duration depends on the type and severity of the infection, typically ranging from 7 to 14 days. Always complete the full course as prescribed by your doctor, even if you feel better, to ensure the infection is fully treated.
How do I dispose of oxacillin?
Dispose of unused oxacillin by taking it to a drug take-back program or collection site at a pharmacy or hospital. If that's not possible, mix the medication with something undesirable, like used coffee grounds, seal it in a plastic bag, and throw it away in the trash. This helps prevent harm to people and the environment.
How do I take oxacillin?
Take oxacillin as prescribed by your doctor. It's usually taken every 4 to 6 hours, either orally or by injection. If taking orally, it should be taken on an empty stomach, 1 hour before or 2 hours after meals. Do not crush or chew the capsules. If you miss a dose, take it as soon as you remember, unless it's almost time for your next dose. In that case, skip the missed dose. Do not double up on doses. Always follow your doctor's specific instructions.
How long does it take for oxacillin to start working?
Oxacillin starts working shortly after you take it, with noticeable improvement in symptoms within a few days. The full therapeutic effect may take longer, depending on the infection's severity and location. Factors like your overall health and the specific bacteria involved can affect how quickly oxacillin works. Always take it as prescribed for the best results.
How should I store oxacillin?
Store oxacillin at room temperature, away from moisture and light. Keep it in a tightly closed container. Do not store it in the bathroom, where humidity can affect the medication. Always keep oxacillin out of reach of children to prevent accidental ingestion. Check the expiration date regularly and dispose of any expired medication properly.
What is the usual dose of oxacillin?
The usual adult dose of oxacillin is 250 mg to 500 mg every 4 to 6 hours, depending on the severity of the infection. For children, the dose is based on body weight and should be determined by a doctor. Dose adjustments may be necessary for elderly patients or those with kidney problems. Always follow your doctor's specific dosing instructions for your health needs.
Warnings and Precautions
Can I take oxacillin with other prescription drugs?
Oxacillin can interact with certain medications, such as probenecid, which can increase oxacillin levels in the blood. This may increase the risk of side effects. Always inform your doctor about all medications you are taking to avoid potential interactions. Your doctor can adjust your treatment plan to ensure safety and effectiveness.
Can oxacillin be taken safely while breastfeeding?
Oxacillin is generally considered safe to use while breastfeeding. It is excreted into breast milk in small amounts, but adverse effects on the breastfed infant are unlikely. Always consult your doctor before taking any medication while breastfeeding to ensure it's safe for you and your baby.
Can oxacillin be taken safely while pregnant?
Oxacillin is generally considered safe during pregnancy, but it's important to use it only if clearly needed. Limited data is available on its use in pregnant women, so always consult your doctor. They will weigh the benefits and risks to ensure the best outcome for you and your baby.
Does oxacillin have adverse effects?
Adverse effects are unwanted reactions to a medication. Common adverse effects of oxacillin include nausea, vomiting, and diarrhea. These effects are usually mild. Serious adverse effects, like severe allergic reactions, are rare but require immediate medical attention. If you notice any new or worsening symptoms while taking oxacillin, contact your doctor.
Does oxacillin have any safety warnings?
Yes, oxacillin has safety warnings. It can cause allergic reactions, especially in people allergic to penicillin. Symptoms include rash, itching, or difficulty breathing, which require immediate medical attention. Not adhering to these warnings can lead to severe allergic reactions. Always inform your doctor of any allergies and follow their guidance closely.
Is it safe to drink alcohol while taking oxacillin?
It's best to avoid alcohol while taking oxacillin. Alcohol can increase the risk of side effects like stomach upset and dizziness. If you choose to drink, do so in moderation and watch for any adverse reactions. Talk with your doctor about alcohol use while taking oxacillin for personalized advice.
Is it safe to exercise while taking oxacillin?
It's generally safe to exercise while taking oxacillin. However, if you experience side effects like dizziness or stomach upset, you might want to avoid strenuous activities. Listen to your body and rest if needed. If you have concerns about exercising while on oxacillin, consult your doctor for personalized advice.
Is it safe to stop oxacillin?
Oxacillin is usually prescribed for short-term use to treat infections. Stopping it early can lead to the infection not being fully treated, which might cause it to return or worsen. Always complete the full course as prescribed by your doctor, even if you feel better. If you have concerns about stopping oxacillin, talk with your doctor.
Is oxacillin addictive?
Oxacillin is not addictive or habit-forming. It does not cause dependency or withdrawal symptoms when you stop taking it. Oxacillin works by killing bacteria and does not affect brain chemistry in ways that could lead to addiction. You won't experience cravings for this medication or feel compelled to take more than prescribed. If you have concerns about medication dependence, you can feel confident that oxacillin doesn't carry this risk.
Is oxacillin safe for the elderly?
Elderly individuals may be more sensitive to the effects of oxacillin, especially if they have kidney problems. Dose adjustments may be necessary. It's important for elderly patients to be closely monitored by their doctor while taking oxacillin to ensure safety and effectiveness. Always follow your doctor's guidance.
What are the most common side effects of oxacillin?
Side effects are unwanted reactions to a medication. Common side effects of oxacillin include nausea, vomiting, and diarrhea. These occur in a small percentage of people and are usually mild. If you experience new symptoms after starting oxacillin, they might be temporary or unrelated to the medication. Talk with your doctor before stopping any medication.
Who should avoid taking oxacillin?
Oxacillin should not be used if you are allergic to it or other penicillin antibiotics. This is an absolute contraindication due to the risk of severe allergic reactions. Use with caution in people with kidney problems, as dose adjustments may be needed. Always inform your doctor of any allergies or health conditions before starting oxacillin.

