Omadacycline
Bacterial Skin Diseases, Bacterial Pneumonia ... show more
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Drug Status
Government Approvals
US(FDA)
WHO Essential Medicine
NO
Known Teratogen
No
Pharmaceutical Class
Tetracycline-class Antibacterial
Controlled Drug Substance
No
Omadacycline
Summary
Omadacycline is used to treat bacterial infections such as community-acquired bacterial pneumonia and acute bacterial skin and skin structure infections. It's not effective against viral infections.
Omadacycline works by binding to the 30S ribosomal subunit of bacteria. This blocks protein synthesis, preventing the bacteria from growing and spreading.
For adults, the usual dose of Omadacycline is 300 mg orally once daily. It's not recommended for children under 18 years of age or during pregnancy.
Common side effects of Omadacycline include nausea, vomiting, diarrhea, constipation, and headache. Serious side effects can include allergic reactions, severe headache, blurred vision, and watery or bloody stools.
Omadacycline should not be used in patients with known hypersensitivity to tetracycline-class drugs. It can cause tooth discoloration and inhibit bone growth in children under 8 and during pregnancy. Avoid unnecessary sun exposure as it may increase skin sensitivity.
Indications and Purpose
How does Omadacycline work?
Omadacycline works by binding to the 30S ribosomal subunit of bacteria, blocking protein synthesis, which prevents the bacteria from growing and spreading.
Is Omadacycline effective?
Omadacycline has been shown to be effective in treating community-acquired bacterial pneumonia and acute bacterial skin and skin structure infections in clinical trials. It works by inhibiting bacterial protein synthesis, which prevents the growth and spread of bacteria.
What is Omadacycline?
Omadacycline is an antibiotic used to treat bacterial infections like pneumonia and skin infections. It belongs to the tetracycline class and works by inhibiting bacterial protein synthesis, preventing bacteria from growing and spreading. It is not effective against viral infections.
Directions for Use
For how long do I take Omadacycline?
Omadacycline is typically taken once a day for 7 to 14 days, depending on the type and severity of the infection being treated.
How do I dispose of Omadacycline?
If you can, bring unused medicines to a drug take-back program or collection site at a pharmacy or hospital. They will dispose of this medicine properly so they don't harm people or the environment. If you can't find a take-back program, you can throw most medicines in the trash at home. But first, take them out of their original containers, mix them with something undesirable like used coffee grounds, seal the mixture in a plastic bag and throw it away.
How do I take Omadacycline?
Omadacycline should be taken on an empty stomach with water, at least 4 hours after eating. Avoid eating or drinking anything except water for 2 hours after taking it, and avoid dairy products for 4 hours after taking the medication.
How long does it take for Omadacycline to start working?
Omadacycline starts working within a few hours, with peak plasma concentration reached in about 2 to 4 hours. Full therapeutic effects may take a few days, depending on the infection. Factors like the type of infection and individual health can affect how quickly it works. Always follow your healthcare provider's instructions for the best results.
How should I store Omadacycline?
Store Omadacycline in its original container, tightly closed, at room temperature away from excess heat and moisture. Keep it out of reach of children.
What is the usual dose of Omadacycline?
For adults, the usual dose of Omadacycline is 300 mg orally once daily. For children, Omadacycline is not recommended for those under 18 years of age due to potential adverse effects on bone growth and teeth discoloration.
Warnings and Precautions
Can I take Omadacycline with other prescription drugs?
Omadacycline's effectiveness can be reduced by antacids containing magnesium, aluminum, or calcium, and iron products. It should be taken 4 hours before or after these substances.
Can Omadacycline be taken safely while breastfeeding?
Breastfeeding is not recommended while taking Omadacycline and for 4 days after the last dose due to potential adverse effects on the infant, such as tooth discoloration and bone growth inhibition.
Can Omadacycline be taken safely while pregnant?
Omadacycline should not be used during pregnancy as it can harm the fetus, causing tooth discoloration and affecting bone growth. Women of childbearing age should use effective birth control while taking this medication.
Does Omadacycline have adverse effects?
Adverse effects are unwanted or harmful effects caused by a medicine. Omadacycline can cause nausea, vomiting, diarrhea, headache, and dizziness. These are not very common but can occur. Rarely, it may cause severe allergic reactions, which need immediate medical attention. If you experience new or worsening symptoms, it's important to talk to your healthcare provider before stopping the medicine.
Does Omadacycline have any safety warnings?
Omadacycline comes with safety warnings. It can cause allergic reactions, so watch for symptoms like rash, itching, or swelling. It may affect liver function, so signs like yellowing of the skin or eyes should be reported. It can also cause diarrhea, which might indicate a more serious intestinal condition. Always inform your doctor of any unusual symptoms while taking this medicine.
Is it safe to drink alcohol while taking Omadacycline?
Most people tolerate Omadacycline well, and occasional alcoholic drinks should not affect the way this medicine works. There are no well-established interactions between Omadacycline and alcohol that would interfere with its effectiveness. However, it's always wise to drink alcohol in moderation and consult your healthcare provider if you have any concerns.
Is it safe to exercise while taking Omadacycline?
Most people tolerate Omadacycline well, and it should not limit your ability to exercise. There are no known symptoms caused by this medicine that would affect exercise capacity, physical strength, or endurance. However, if you experience any unusual symptoms during physical activity, it's wise to take precautions and consult your healthcare provider.
Is it safe to stop Omadacycline?
Omadacycline is typically used for treating temporary or acute conditions like infections. Stopping it abruptly can lead to the infection not being fully treated, which might cause it to return or worsen. There are no known withdrawal symptoms, but it's crucial to complete the prescribed course to ensure effectiveness. Always consult your doctor before stopping any medication to avoid complications.
Is Omadacycline addictive?
Omadacycline has no known potential for dependence or addiction. It is an antibiotic used to treat infections and does not affect the brain in a way that would cause addiction. You can take it as prescribed without worrying about becoming addicted.
Is Omadacycline safe for the elderly?
Elderly patients, especially those over 65, should be closely monitored when taking Omadacycline, as there is a higher risk of mortality in this age group. Consult your doctor for personalized advice.
What are the most common side effects of Omadacycline?
A side effect is an unwanted reaction to a medicine. Common side effects of Omadacycline include nausea, vomiting, diarrhea, headache, and dizziness. These are not very common but can happen. It's important to know that new symptoms might not be related to the medicine and could be temporary. Always talk to your healthcare provider before stopping any medicine.
Who should avoid taking Omadacycline?
Omadacycline should not be used in patients with known hypersensitivity to tetracycline-class drugs. It can cause tooth discoloration and inhibit bone growth in children under 8 and during pregnancy. Avoid unnecessary sun exposure, as it may increase skin sensitivity.
