odevixibat
Pruritus
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Drug Status
Government Approvals
UK(BNF)
WHO Essential Medicine
NO
Known Teratogen
No
Pharmaceutical Class
Ileal Bile Acid Transporter Inhibitor
Controlled Drug Substance
No
Summary
Odevixibat is used to treat progressive familial intrahepatic cholestasis, which is a liver disorder affecting bile flow. It helps reduce bile acid levels, improving liver function and reducing symptoms like itching. Odevixibat is used as a complementary addition to other therapies for managing liver conditions.
Odevixibat works by inhibiting the ileal bile acid transporter, which reduces the reabsorption of bile acids in the intestines. This process helps lower bile acid levels in the liver and intestines, improving liver function. Think of it like a sponge soaking up excess liquid; odevixibat helps remove excess bile acids, reducing liver stress.
Odevixibat is typically taken once daily, as directed by your doctor. You can take it with or without food. If you miss a dose, take it as soon as you remember unless it's almost time for your next dose. In that case, skip the missed dose and continue your regular schedule. Do not take two doses at once.
Common side effects of odevixibat include diarrhea and abdominal pain, which are unwanted reactions to the medication. These effects vary from person to person. If you notice new symptoms after starting odevixibat, they might be temporary or unrelated to the medication. Talk with your doctor before stopping any medication.
Odevixibat can cause liver problems, so regular liver function tests are recommended. If you experience symptoms like jaundice, which is yellowing of the skin or eyes, or severe abdominal pain, contact your doctor immediately. Not adhering to these warnings can lead to serious health issues. Always follow your doctor's advice and report any unusual symptoms.
Indications and Purpose
How does odevixibat work?
Odevixibat works by inhibiting the ileal bile acid transporter, which reduces the reabsorption of bile acids in the intestines. This process helps lower bile acid levels in the liver and intestines, improving liver function. Think of it like a sponge soaking up excess liquid; odevixibat helps remove excess bile acids, reducing liver stress. This medication is effective for conditions like progressive familial intrahepatic cholestasis.
Is odevixibat effective?
Odevixibat is effective for treating certain liver conditions, such as progressive familial intrahepatic cholestasis, which is a liver disorder that affects bile flow. Clinical studies show that odevixibat can improve bile acid levels and liver function in patients with this condition. Always follow your doctor's advice and attend regular check-ups to monitor your progress and ensure the medication is working effectively.
What is odevixibat?
Odevixibat is a medication used to treat liver conditions like progressive familial intrahepatic cholestasis, which is a liver disorder affecting bile flow. It works by reducing bile acid levels in the liver and intestines, helping to improve liver function. Odevixibat is part of a class of medications called ileal bile acid transporter inhibitors. It is used as a complementary addition to other therapies for managing liver conditions.
Directions for Use
For how long do I take odevixibat?
Odevixibat is usually a long-term medication for managing chronic liver conditions like progressive familial intrahepatic cholestasis. You'll typically take odevixibat every day as a lifelong treatment unless your doctor suggests otherwise. How long you'll need this medication depends on your body's response, any side effects you experience, and changes in your overall health. Always talk with your doctor before changing or stopping your odevixibat treatment.
How do I dispose of odevixibat?
If you can, bring unused odevixibat to a drug take-back program or collection site at a pharmacy or hospital. They will dispose of this medicine properly so it doesn't harm people or the environment. If you can't find a take-back program, you can throw most medicines in the trash at home. But first, take them out of their original containers, mix them with something undesirable like used coffee grounds, seal the mixture in a plastic bag, and throw it away.
How do I take odevixibat?
Take odevixibat as directed by your doctor, usually once daily. You can take it with or without food. If you miss a dose, take it as soon as you remember unless it's almost time for your next dose. In that case, skip the missed dose and continue your regular schedule. Do not take two doses at once. Always follow your doctor's specific instructions regarding diet and fluid intake while on this medication.
How long does it take for odevixibat to start working?
Odevixibat begins working in your body shortly after you take it, but you may not notice all the benefits right away. For liver conditions, improvements in symptoms like itching may take several weeks. The full therapeutic effect on liver function may take months to appear. How quickly the medication works can depend on your overall health and the severity of your condition. Take it exactly as prescribed for the best results.
How should I store odevixibat?
Store odevixibat at room temperature, away from moisture and light. Keep it in a tightly closed container to protect it from damage. Don't store your medicine in humid places like bathrooms, where moisture in the air could affect how well the medication works. Always store odevixibat out of children's reach to prevent accidental swallowing. Check the expiration date regularly and properly dispose of any unused or expired medication.
What is the usual dose of odevixibat?
The usual starting dose of odevixibat for adults is determined by your doctor based on your specific condition. It's typically taken once daily. Your doctor may adjust your dose as needed. Always follow your doctor's specific dosing instructions for your personal health needs. If you have any questions about your dosage, consult your healthcare provider.
Warnings and Precautions
Can I take odevixibat with other prescription drugs?
Odevixibat may interact with other medications, increasing the risk of side effects or reducing effectiveness. Always inform your doctor about all the medicines you take, including over-the-counter drugs and supplements. Your doctor can help identify potential interactions and adjust your treatment plan accordingly. Regular check-ups ensure your treatment remains safe and effective.
Can odevixibat be taken safely while breastfeeding?
The safety of odevixibat while breastfeeding is not well-established. It's unclear if this medication passes into breast milk. If you're taking odevixibat and want to breastfeed, talk with your doctor about safer medication options that would allow you to nurse your baby safely. Your doctor can help determine the best course of action for you and your baby.
Can odevixibat be taken safely while pregnant?
The safety of odevixibat during pregnancy is not well-established. Limited data is available, so it's important to weigh the benefits and risks with your doctor. If you're pregnant or planning to become pregnant, talk with your doctor about the safest way to manage your condition during this important time. Your doctor can help create a pregnancy-specific treatment plan that protects both you and your baby.
Does odevixibat have adverse effects?
Adverse effects are unwanted reactions to a medication. With odevixibat, common adverse effects include diarrhea and abdominal pain. These effects vary in frequency and severity. Serious side effects are rare but can include liver problems. If you notice any new or worsening symptoms, contact your doctor. They can help determine if these symptoms are related to odevixibat and suggest appropriate actions.
Does odevixibat have any safety warnings?
Odevixibat has important safety warnings. It can cause liver problems, so regular liver function tests are recommended. If you experience symptoms like jaundice, which is yellowing of the skin or eyes, or severe abdominal pain, contact your doctor immediately. Not adhering to these warnings can lead to serious health issues. Always follow your doctor's advice and report any unusual symptoms.
Is it safe to drink alcohol while taking odevixibat?
It's best to avoid alcohol while taking odevixibat. Alcohol can affect liver function and may worsen side effects of odevixibat. If you do choose to drink occasionally, limit how much alcohol you consume and watch for warning signs like nausea or abdominal pain. Talk with your doctor about alcohol use while taking odevixibat to get personalized advice based on your specific health situation.
Is it safe to exercise while taking odevixibat?
You can exercise while taking odevixibat, but keep a few things in mind. This medication can cause diarrhea, which might make you feel weak during workouts. To exercise safely, drink plenty of water before, during, and after physical activity. Watch for signs of dizziness or unusual fatigue. If you notice these symptoms, slow down or stop exercising and rest. Check with your doctor if you have concerns about your specific situation.
Is it safe to stop odevixibat?
Odevixibat is usually used for long-term management of chronic conditions. Stopping it suddenly can cause your symptoms to return or worsen. Always talk with your doctor before stopping odevixibat. They might suggest gradually reducing your dose or switching to a different medication to keep your condition under control. Your doctor will help you make any medication changes safely.
Is odevixibat addictive?
Odevixibat is not addictive or habit-forming. This medication doesn't cause dependency or withdrawal symptoms when you stop taking it. You won't experience cravings for this medication or feel compelled to take more than prescribed. If you have concerns about medication dependence, you can feel confident that odevixibat doesn't carry this risk.
Is odevixibat safe for the elderly?
The elderly may be more vulnerable to the side effects of odevixibat, such as diarrhea and abdominal pain. These side effects can lead to dehydration, which is when your body doesn't have enough fluids. It's important for elderly patients to stay well-hydrated and report any unusual symptoms to their doctor. Regular check-ups help ensure the medication is working safely and effectively.
What are the most common side effects of odevixibat?
Side effects are unwanted reactions that can happen when taking a medication. Common side effects of odevixibat include diarrhea and abdominal pain. These effects vary from person to person. If you notice new symptoms after starting odevixibat, they might be temporary or unrelated to the medication. Talk with your doctor before stopping any medication.
Who should avoid taking odevixibat?
Don't take odevixibat if you're allergic to it or its ingredients. Serious allergic reactions, which cause rash, hives, or swelling that makes breathing difficult, require immediate medical help. Odevixibat should be used with caution in patients with liver problems. Always consult your doctor about these concerns and inform them of any other medications you are taking.
