Montelukast
Perennial Allergic Rhinitis, Asthma
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Drug Status
Government Approvals
US(FDA), UK(BNF)
WHO Essential Medicine
NO
Known Teratogen
NO
Pharmaceutical Class
Leukotriene Receptor Antagonist
Controlled Drug Substance
NO
Montelukast
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Click HereSummary
Montelukast is used for the prevention and chronic treatment of asthma, prevention of exercise-induced bronchoconstriction, and relief of symptoms of seasonal and perennial allergic rhinitis.
Montelukast works by blocking leukotriene receptors in your body. Leukotrienes cause inflammation, constriction of airways, and mucus production. By blocking these, Montelukast reduces asthma symptoms and allergic reactions.
For adults and adolescents 15 years and older, the usual dose is 10 mg once daily. For children aged 6 to 14 years, it's typically 5 mg once daily, and for children aged 2 to 5 years, the dose is 4 mg once daily.
Common side effects include headache, stomach pain, and diarrhea. Serious adverse effects can include mental health changes like depression and suicidal thoughts.
Montelukast may cause serious mental health changes, including suicidal thoughts and behavior. It's not for treating sudden asthma attacks. If you experience any changes in behavior, contact your doctor immediately.
Indications and Purpose
What is Montelukast used for?
Montelukast is indicated for the prevention and chronic treatment of asthma, the prevention of exercise-induced bronchoconstriction, and the relief of symptoms of seasonal and perennial allergic rhinitis. It helps manage these conditions by reducing inflammation and improving breathing.
How does Montelukast work?
Montelukast works by blocking leukotriene receptors in the body. Leukotrienes are chemicals that cause inflammation, constriction of airways, and mucus production. By inhibiting these substances, Montelukast helps reduce asthma symptoms and allergic reactions.
Is Montelukast effective?
Clinical trials have shown that Montelukast effectively improves lung function and reduces asthma symptoms. It also helps manage symptoms of allergic rhinitis. The medication works by blocking substances in the body that cause inflammation and constriction of airways.
How does one know if Montelukast is working?
The benefit of Montelukast is evaluated by monitoring the improvement in asthma symptoms, such as reduced frequency of attacks and improved lung function, as well as relief from allergic rhinitis symptoms. Regular follow-ups with a healthcare provider help assess its effectiveness.
Directions for Use
What is the usual dose of Montelukast?
For adults and adolescents 15 years and older, the usual dose of Montelukast is 10 mg once daily. For children aged 6 to 14 years, the dose is typically 5 mg once daily. For children aged 2 to 5 years, the dose is 4 mg once daily. Always follow your doctor's specific instructions for dosing.
How do I take Montelukast?
Montelukast can be taken with or without food. It should be taken at the same time each day for consistency. There are no specific food restrictions, but always follow your doctor's instructions regarding diet and medication use.
For how long do I take Montelukast?
Montelukast is typically used as a long-term treatment for asthma and allergic rhinitis. It is important to continue taking it even if symptoms improve, as it helps manage the condition over time. Always follow your doctor's guidance on the duration of use.
How long does it take for Montelukast to start working?
Montelukast typically starts working within one day of starting treatment. However, it may take a few weeks to notice the full benefits. Consistent daily use is important for managing symptoms effectively.
How should I store Montelukast?
Store Montelukast in its original container at room temperature, away from light and moisture. Keep it out of reach of children. Do not store it in the bathroom, and ensure the container is tightly closed to maintain the medication's effectiveness.
Warnings and Precautions
Who should avoid taking Montelukast?
Montelukast may cause serious mental health changes, including suicidal thoughts and behavior. It is not for treating sudden asthma attacks. Patients should be aware of potential neuropsychiatric events and report any changes in behavior to their doctor immediately.
Can I take Montelukast with other prescription drugs?
Montelukast may interact with drugs like phenobarbital and rifampin, which can affect its metabolism. Always inform your doctor about all medications you are taking to avoid potential interactions and ensure the safe use of Montelukast.
Can I take Montelukast with vitamins or supplements?
From all available and reliable information, there is no confirmed data on this. Please consult a doctor for personalized advice.
Can Montelukast be taken safely while pregnant?
Available data from studies have not established a risk of major birth defects with Montelukast use during pregnancy. However, it should only be used if clearly needed. Always consult your doctor to weigh the benefits and risks before using Montelukast during pregnancy.
Can Montelukast be taken safely while breastfeeding?
Montelukast is present in human milk, but available data do not suggest a significant risk to breastfed infants. The benefits of breastfeeding should be considered along with the mother's need for Montelukast and any potential effects on the infant.
Is Montelukast safe for the elderly?
Montelukast is generally safe for elderly patients, with no specific dosage adjustments required. However, as with any medication, elderly patients should be monitored for side effects, and any unusual symptoms should be reported to a healthcare provider.
Is it safe to exercise while taking Montelukast?
Montelukast is used to prevent exercise-induced bronchoconstriction, meaning it helps improve the ability to exercise by reducing breathing difficulties during physical activity. It should be taken at least 2 hours before exercise for optimal effect.
Is it safe to drink alcohol while taking Montelukast?
From all available and reliable information, there is no confirmed data on this. Please consult a doctor for personalized advice.
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