Mirabegron
Overactive Urinary Bladder, Urge Urinary Incontinence
.svg)
Drug Status
Government Approvals
US(FDA), UK(BNF)
WHO Essential Medicine
NO
Known Teratogen
No
Pharmaceutical Class
Beta3-Adrenergic Agonist
Controlled Drug Substance
No
Mirabegron
Summary
Mirabegron is used to treat overactive bladder symptoms, which include frequent urination, urgency, and incontinence, which is the inability to control urination.
Mirabegron works by relaxing the bladder muscle, which allows it to hold more urine. It belongs to a class of drugs called beta-3 adrenergic agonists, which help reduce urgency and frequency of urination.
The usual starting dose of Mirabegron for adults is 25 mg once daily, which may be adjusted by your doctor. It is taken orally, which means by mouth, and can be taken with or without food.
Common adverse effects of Mirabegron include increased blood pressure and urinary tract infections, which occur in a small percentage of users.
Mirabegron can increase blood pressure, so regular monitoring is important. It is contraindicated in people with severe uncontrolled high blood pressure and severe liver or kidney impairment.
Indications and Purpose
How does Mirabegron work?
Mirabegron works by relaxing the bladder muscle, allowing it to hold more urine. It belongs to a class of drugs called beta-3 adrenergic agonists. Think of it like loosening a tight rubber band, allowing more space for urine. This helps reduce the urgency and frequency of urination in people with overactive bladder.
Is Mirabegron effective?
Mirabegron is effective for treating overactive bladder symptoms, such as frequent urination and urgency. It works by relaxing the bladder muscle, allowing it to hold more urine. Clinical studies show that Mirabegron significantly reduces the number of bathroom trips and urgency episodes. This makes it a beneficial treatment for people with overactive bladder.
What is Mirabegron?
Mirabegron is a medication used to treat overactive bladder symptoms, such as frequent urination and urgency. It belongs to a class of drugs called beta-3 adrenergic agonists, which work by relaxing the bladder muscle to help it fill and store urine. This reduces the number of bathroom trips and urgency episodes.
Directions for Use
For how long do I take Mirabegron?
Mirabegron is usually a long-term medication for managing overactive bladder symptoms. You'll typically take it every day as a lifelong treatment unless your doctor suggests otherwise. How long you'll need this medication depends on your body's response and any side effects you experience. Always talk with your doctor before changing or stopping your Mirabegron treatment.
How do I dispose of Mirabegron?
Dispose of unused Mirabegron by taking it to a drug take-back program or collection site at a pharmacy or hospital. If you can't find a take-back program, you can throw it in the trash at home. First, mix it with something undesirable like used coffee grounds, seal it in a plastic bag, and then throw it away.
How do I take Mirabegron?
Take Mirabegron as prescribed by your doctor, usually once daily. You can take it with or without food. Swallow the tablet whole; do not crush or chew it. If you miss a dose, take it as soon as you remember unless it's almost time for your next dose. In that case, skip the missed dose and continue your regular schedule. Do not take two doses at once. Always follow your doctor's specific instructions.
How long does it take for Mirabegron to start working?
Mirabegron begins working in your body shortly after you take it, but it may take several weeks to notice significant improvements in overactive bladder symptoms. Individual factors like age and overall health can affect how quickly you see results. Take it exactly as prescribed for the best results.
How should I store Mirabegron?
Store Mirabegron at room temperature, away from moisture and light. Keep it in a tightly closed container. Avoid storing it in humid places like bathrooms. If your pills came in packaging that isn't child-resistant, transfer them to a container that children can't easily open. Always store Mirabegron out of children's reach.
What is the usual dose of Mirabegron?
The usual starting dose of Mirabegron for adults is 25 mg once daily. Your doctor may adjust your dose based on your response and needs. The maximum recommended dose is 50 mg daily. Always follow your doctor's specific dosing instructions. Special populations, such as the elderly or those with kidney problems, may require dose adjustments.
Warnings and Precautions
Can I take Mirabegron with other prescription drugs?
Mirabegron can interact with certain medications, such as anticholinergic drugs, which may increase the risk of urinary retention. It can also interact with medications that affect liver enzymes, potentially altering Mirabegron's effectiveness. Always inform your doctor about all the medications you take to avoid potential interactions and ensure safe treatment.
Can Mirabegron be taken safely while breastfeeding?
The safety of Mirabegron while breastfeeding is not well-established. It's unclear if the medication passes into breast milk. If you're breastfeeding or planning to breastfeed, talk with your doctor about safer medication options. Your doctor can help you choose a treatment that allows you to nurse your baby safely.
Can Mirabegron be taken safely while pregnant?
The safety of Mirabegron during pregnancy is not well-established. Limited data is available, so it's best to avoid using it unless absolutely necessary. If you're pregnant or planning to become pregnant, talk with your doctor about the safest treatment options for managing your condition during pregnancy.
Does Mirabegron have adverse effects?
Adverse effects are unwanted reactions to a medication. Common adverse effects of Mirabegron include increased blood pressure and urinary tract infections. These occur in a small percentage of users. Serious side effects, like severe allergic reactions or heart palpitations, are rare. If you notice any new or worsening symptoms, contact your doctor immediately for advice.
Does Mirabegron have any safety warnings?
Yes, Mirabegron has safety warnings. It can increase blood pressure, so regular monitoring is important. It may also cause urinary retention, which is when you can't empty your bladder completely. If you experience symptoms like difficulty urinating or high blood pressure, contact your doctor. Not adhering to these warnings can lead to serious health issues.
Is it safe to drink alcohol while taking Mirabegron?
It's best to limit alcohol consumption while taking Mirabegron. Alcohol can increase the risk of side effects like dizziness or increased blood pressure. If you choose to drink, do so in moderation and watch for any unusual symptoms. Talk with your doctor about alcohol use while taking Mirabegron for personalized advice.
Is it safe to exercise while taking Mirabegron?
You can exercise while taking Mirabegron, but be mindful of your body's response. This medication can increase blood pressure, so monitor your heart rate and blood pressure during physical activity. If you feel dizzy or lightheaded, slow down or stop exercising and rest. Consult your doctor if you have concerns about exercising while on Mirabegron.
Is it safe to stop Mirabegron?
Mirabegron is usually used for long-term management of overactive bladder symptoms. Stopping it suddenly may cause your symptoms to return or worsen. Always talk with your doctor before stopping Mirabegron. They might suggest gradually reducing your dose or switching to a different medication to manage your condition safely.
Is Mirabegron addictive?
Mirabegron is not addictive or habit-forming. It doesn't cause dependency or withdrawal symptoms when you stop taking it. Mirabegron works by relaxing the bladder muscle to help it fill and store urine. This mechanism doesn't affect brain chemistry in ways that could lead to addiction. You won't experience cravings for this medication or feel compelled to take more than prescribed.
Is Mirabegron safe for the elderly?
Elderly individuals may be more sensitive to the effects of Mirabegron, especially regarding blood pressure increases. It's important to monitor blood pressure regularly. The elderly may also be at higher risk for urinary retention. Always consult a doctor before starting Mirabegron to ensure it's safe based on individual health conditions.
What are the most common side effects of Mirabegron?
Side effects are unwanted reactions that can happen when taking a medication. Common side effects of Mirabegron include increased blood pressure and urinary tract infections. These occur in a small percentage of users. If you notice new symptoms after starting Mirabegron, they might be temporary or unrelated to the medication. Talk with your doctor before stopping any medication.
Who should avoid taking Mirabegron?
Do not take Mirabegron if you have severe uncontrolled high blood pressure, as it can increase blood pressure. It's also contraindicated in people with severe liver or kidney impairment. If you're allergic to Mirabegron or its ingredients, avoid using it. Always consult your doctor about any health conditions before starting Mirabegron.
Forms / Brands
