Metoprolol succinate
Hypertension, Angina Pectoris ... show more
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Drug Status
Government Approvals
US(FDA), UK(BNF)
WHO Essential Medicine
NO
Known Teratogen
NO
Pharmaceutical Class
Beta-Adrenergic Blocker
Controlled Drug Substance
NO
Metoprolol succinate
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Click HereSummary
Metoprolol succinate is used to treat high blood pressure, chest pain (angina), and heart failure. It can also help prevent heart attacks.
Metoprolol succinate is a beta-blocker. It works by blocking certain signals in the heart, which slows the heart rate and reduces the heart's workload, thereby lowering blood pressure and preventing chest pain.
The dosage of Metoprolol succinate depends on the condition being treated. For high blood pressure, the starting dose is usually 25-100 mg once daily, with a maximum of 400 mg/day. For angina, it's 100-400 mg once daily. For heart failure, you start with 12.5-25 mg once daily and gradually increase to a target dose of 200 mg/day as tolerated. The medicine is taken orally, ideally with food.
Common side effects of Metoprolol succinate include tiredness, dizziness, depression, diarrhea, shortness of breath, slow heartbeat, and rash. More serious but less common side effects include worsening chest pain, heart attack, or heart failure.
Do not stop taking Metoprolol succinate suddenly without talking to your doctor, as this can cause serious heart problems. Avoid driving or operating machinery until you know how the medicine affects you. Also, avoid alcohol as it can increase the risk of side effects. If you have heart failure, tell your doctor if you gain weight or have shortness of breath.
Indications and Purpose
How does Metoprolol succinate work?
Metoprolol succinate works by blocking beta-adrenergic receptors in the heart, which reduces the effects of adrenaline. This leads to a slower heart rate and decreased force of heart contractions, resulting in lower blood pressure and improved blood flow. It also helps reduce the heart's oxygen demand, alleviating angina symptoms.
How does one know if Metoprolol succinate is working?
The benefit of Metoprolol succinate is evaluated by monitoring blood pressure, heart rate, and symptoms of angina or heart failure. Regular follow-up appointments with your doctor are important to assess the effectiveness and adjust the dosage if necessary. Self-monitoring of blood pressure at home can also be helpful.
Is Metoprolol succinate effective?
Metoprolol succinate has been shown in clinical trials to effectively lower blood pressure, reduce angina attacks, and improve survival rates after heart attacks. It works by relaxing blood vessels and slowing the heart rate, which improves blood flow and decreases blood pressure. These benefits have been consistently observed in various studies.
What is Metoprolol succinate?
Metoprolol succinate is commonly used to treat high blood pressure, angina, and heart failure. It belongs to a class of medications called beta-blockers, which work by relaxing blood vessels and slowing the heart rate to improve blood flow and decrease blood pressure. This helps reduce the risk of heart attacks and strokes.
What is Metoprolol succinate used for?
Metoprolol succinate is indicated for the treatment of high blood pressure, angina pectoris, and heart failure. It is also used to improve survival after a heart attack and may be prescribed for certain types of irregular heartbeats. Always consult your doctor for specific indications and treatment plans.
Directions for Use
For how long do I take Metoprolol succinate?
Metoprolol succinate is typically used as a long-term treatment for conditions like hypertension, angina, and heart failure. The duration of use depends on the individual's condition and response to treatment. It's important to follow your doctor's guidance and not stop taking the medication without consulting them.
How do I dispose of Metoprolol succinate?
If you can, bring unused medicines to a drug take-back program or collection site at a pharmacy or hospital. They will dispose of this medicine properly so they don't harm people or the environment. If you can't find a take-back program, you can throw most medicines in the trash at home. But first, take them out of their original containers, mix them with something undesirable like used coffee grounds, seal the mixture in a plastic bag and throw it away.
How do I take Metoprolol succinate?
Metoprolol succinate should be taken with or immediately after meals to enhance absorption. There are no specific food restrictions, but it's important to maintain a healthy diet low in fat and salt to support blood pressure management. Always follow your doctor's instructions regarding dosage and administration.
How long does it take for Metoprolol succinate to start working?
Metoprolol succinate begins to work within a few hours of taking the first dose, but it may take a week or more to see the full effect on blood pressure. For heart failure or angina, it may take longer to notice improvements. Consistent use as prescribed is important for optimal results.
How should I store Metoprolol succinate?
Store Metoprolol succinate in its original container, tightly closed, at room temperature away from excess heat and moisture. Keep it out of reach of children. Do not store it in the bathroom. For disposal, use a medicine take-back program to prevent accidental ingestion by pets or children.
What is the usual dose of Metoprolol succinate?
For adults, the usual initial dose of Metoprolol succinate for hypertension is 25 mg to 100 mg once daily. For children aged 6 years and older, the starting dose is 1 mg/kg once daily, not exceeding 50 mg initially. Dosage adjustments are made based on the patient's response and can be increased gradually. Always follow your doctor's specific instructions.
Warnings and Precautions
Can I take Metoprolol succinate with other prescription drugs?
Metoprolol succinate can interact with catecholamine depleting drugs, CYP2D6 inhibitors, and other medications like digitalis, clonidine, and calcium channel blockers, increasing the risk of bradycardia and hypotension. Always inform your doctor about all medications and supplements you are taking to avoid potential interactions.
Can I take Metoprolol succinate with vitamins or supplements?
There are no well-documented interactions between Metoprolol succinate and vitamins or supplements. However, it's important to inform your healthcare provider about all supplements you're taking. This helps them monitor for any potential interactions or nutrient depletions. Always consult your healthcare provider before starting any new supplements while on this medicine.
Can Metoprolol succinate be taken safely while breastfeeding?
Metoprolol succinate is present in breast milk, but the amount is generally low. No adverse effects on breastfed infants have been identified. However, monitor the infant for signs of beta-blockade, such as bradycardia. Consult your doctor for personalized advice if you are breastfeeding while taking this medication.
Can Metoprolol succinate be taken safely while pregnant?
Metoprolol succinate should be used during pregnancy only if clearly needed, as untreated hypertension poses risks to both mother and fetus. Available data do not show a significant risk of major birth defects, but there are reports of intrauterine growth restriction. Always consult your doctor for personalized advice during pregnancy.
Does Metoprolol succinate have adverse effects?
Adverse effects are unwanted or harmful effects caused by a medicine. Metoprolol succinate can cause dizziness, fatigue, depression, shortness of breath, and slow heart rate. These effects are not very common but can occur. Rarely, it can cause severe allergic reactions or heart problems that need immediate medical attention. Always report new symptoms to your healthcare provider and never stop the medicine without consulting them.
Does Metoprolol succinate have any safety warnings?
Metoprolol succinate comes with safety warnings. It can cause dizziness or fatigue, so be cautious when driving or operating machinery. It may also mask signs of low blood sugar in diabetics. Watch for symptoms like unusual tiredness or slow heart rate. If you experience severe side effects, contact your doctor immediately. Always follow your healthcare provider's advice and report any new symptoms.
Is it safe to drink alcohol while taking Metoprolol succinate?
Drinking alcohol while taking Metoprolol succinate can increase the risk of side effects such as dizziness and drowsiness. Alcohol may also affect how the medication is released from extended-release formulations, potentially leading to increased side effects. It's advisable to avoid alcohol or consult your doctor for personalized advice.
Is it safe to exercise while taking Metoprolol succinate?
Metoprolol succinate can cause fatigue and dizziness, which may affect your ability to exercise. However, it is often prescribed to improve heart function, which can enhance exercise tolerance over time. If you experience significant limitations, consult your doctor for advice.
Is it safe to stop Metoprolol succinate?
Metoprolol succinate is often used for long-term management of chronic conditions like hypertension. Stopping it suddenly can lead to serious risks, such as a rapid increase in blood pressure or heart rate, which can be life-threatening. You might also experience withdrawal symptoms. It's crucial to consult your doctor before stopping this medicine to safely reduce the dose if needed.
Is Metoprolol succinate addictive?
Metoprolol succinate is not addictive and has no habit-forming potential. There are no known behaviors or warning signs of dependence associated with this medicine. You can take it as prescribed without worrying about addiction. Always follow your healthcare provider's instructions and consult them if you have any concerns.
Is Metoprolol succinate safe for the elderly?
Elderly patients may be more sensitive to the effects of Metoprolol succinate, particularly its impact on heart rate and blood pressure. It's important to start with a lower dose and adjust gradually under medical supervision. Regular monitoring of heart function and blood pressure is recommended to ensure safe use.
What are the most common side effects of Metoprolol succinate?
A side effect is an unwanted reaction to a medicine. Common side effects of Metoprolol succinate include tiredness, dizziness, depression, shortness of breath, and slow heart rate. These effects are not very common but can happen. When starting a new medicine, you might notice new symptoms that could be unrelated or temporary. Always talk to your healthcare provider before stopping any medicine.
Who should avoid taking Metoprolol succinate?
Metoprolol succinate is contraindicated in patients with severe bradycardia, heart block, cardiogenic shock, and decompensated heart failure. Abrupt cessation can worsen angina or cause heart attacks. Patients with asthma, diabetes, or thyroid disorders should use it cautiously. Always consult a doctor before starting or stopping the medication.
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