Lusutrombopag
Thrombocytopenia
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Drug Status
Government Approvals
US(FDA), UK(BNF)
WHO Essential Medicine
NO
Known Teratogen
No
Pharmaceutical Class
NA
Controlled Drug Substance
No
Lusutrombopag
Summary
Lusutrombopag is used to increase platelet counts in patients with chronic liver disease, which is a long-term liver condition, who are undergoing medical procedures. It helps reduce the need for platelet transfusions, which are procedures to increase platelet levels in the blood.
Lusutrombopag works by stimulating the production of platelets, which are small blood cells that help with clotting. It acts on the thrombopoietin receptor, which is a protein that regulates platelet production in the bone marrow.
The usual starting dose of Lusutrombopag for adults is 3 mg once daily. It is taken orally, which means by mouth, and can be taken with or without food. It's important to follow your doctor's specific dosing instructions.
Common side effects of Lusutrombopag include headache and nausea, which is a feeling of sickness with an inclination to vomit. These effects vary from person to person and are usually mild.
Lusutrombopag can increase the risk of blood clots, which are clumps of blood that can block blood vessels. It should not be used if you have a known allergy to it or its ingredients. Always consult your doctor about any concerns.
Indications and Purpose
How does Lusutrombopag work?
Lusutrombopag works by stimulating the production of platelets, which are small blood cells that help with clotting. It acts on the thrombopoietin receptor, which is a protein that regulates platelet production in the bone marrow. Think of it like turning up the volume on a radio to increase the sound. This medication helps increase platelet counts in patients with chronic liver disease undergoing medical procedures.
Is Lusutrombopag effective?
Lusutrombopag is effective in increasing platelet counts in patients with chronic liver disease who are undergoing medical procedures. Clinical studies show that it helps reduce the need for platelet transfusions, which are procedures to increase platelet levels in the blood. This medication is specifically designed to manage low platelet counts in these patients.
What is Lusutrombopag?
Lusutrombopag is a medication used to increase platelet counts in patients with chronic liver disease who are undergoing medical procedures. It belongs to a class of drugs called thrombopoietin receptor agonists, which stimulate the production of platelets. This helps reduce the need for platelet transfusions, which are procedures to increase platelet levels in the blood.
Directions for Use
For how long do I take Lusutrombopag?
Lusutrombopag is usually taken for a short period before a medical procedure to increase platelet counts. The duration of use depends on your specific health needs and your doctor's recommendations. Always follow your doctor's instructions on how long to take this medication. Do not stop taking it without consulting your healthcare provider.
How do I dispose of Lusutrombopag?
To dispose of Lusutrombopag, bring unused medicines to a drug take-back program or collection site at a pharmacy or hospital. They will dispose of this medicine properly so it doesn't harm people or the environment. If you can't find a take-back program, you can throw most medicines in the trash at home. Mix them with something undesirable like used coffee grounds, seal the mixture in a plastic bag, and throw it away.
How do I take Lusutrombopag?
Lusutrombopag is usually taken once daily. You can take it with or without food. It's important to follow your doctor's instructions on how to take this medication. If you miss a dose, take it as soon as you remember unless it's almost time for your next dose. In that case, skip the missed dose and continue your regular schedule. Do not take two doses at once. Always follow your doctor's specific advice about diet and fluid intake while taking this medication.
How long does it take for Lusutrombopag to start working?
Lusutrombopag starts working within a few days to increase platelet counts. The full therapeutic effect is usually achieved within 7 to 14 days. Individual factors like your overall health and response to the medication can affect how quickly it works. Follow your doctor's instructions and attend regular check-ups to monitor your progress.
How should I store Lusutrombopag?
Store Lusutrombopag at room temperature, away from moisture and light. Keep it in its original packaging until you're ready to take it. Avoid storing it in humid places like bathrooms. Always keep it out of reach of children to prevent accidental ingestion. Check the expiration date regularly and properly dispose of any unused or expired medication.
What is the usual dose of Lusutrombopag?
The usual starting dose of Lusutrombopag for adults is typically 3 mg once daily. It's important to follow your doctor's specific dosing instructions for your personal health needs. Your doctor may adjust your dose based on your response to the medication and any side effects you experience. Always consult your healthcare provider for guidance tailored to your situation.
Warnings and Precautions
Can I take Lusutrombopag with other prescription drugs?
Lusutrombopag may interact with other medications that affect blood clotting, increasing the risk of bleeding. It's important to inform your doctor about all the medications you are taking, including over-the-counter drugs and supplements. Your doctor will help manage any potential interactions to ensure your treatment is safe and effective.
Can Lusutrombopag be taken safely while breastfeeding?
The safety of Lusutrombopag while breastfeeding is not well-established. It's unclear if this medication passes into breast milk. If you're breastfeeding or planning to breastfeed, talk with your doctor about the safest options for you and your baby. Your doctor can help determine the best treatment plan for your situation.
Can Lusutrombopag be taken safely while pregnant?
The safety of Lusutrombopag during pregnancy is not well-established. There is limited information on its use in pregnant women. If you're pregnant or planning to become pregnant, talk with your doctor about the safest way to manage your condition. Your doctor can help create a treatment plan that protects both you and your baby.
Does Lusutrombopag have adverse effects?
Adverse effects are unwanted reactions that can occur with medication use. Lusutrombopag can cause some adverse effects, though most people tolerate it well. Common adverse effects include headache and nausea. Serious adverse effects, like blood clots, require immediate medical attention. Always inform your doctor about any new or worsening symptoms while taking Lusutrombopag.
Does Lusutrombopag have any safety warnings?
Lusutrombopag has important safety warnings. It can increase the risk of blood clots, which are clumps of blood that can block blood vessels. If you experience symptoms like chest pain, shortness of breath, or swelling in your legs, seek medical help immediately. It's crucial to follow your doctor's instructions and attend regular check-ups to monitor your health while taking this medication.
Is it safe to drink alcohol while taking Lusutrombopag?
It's best to avoid alcohol while taking Lusutrombopag. Alcohol can increase the risk of bleeding, which is a concern for patients with low platelet counts. If you do choose to drink occasionally, limit how much alcohol you consume and watch for any unusual symptoms. Talk with your doctor about alcohol use while taking Lusutrombopag for personalized advice.
Is it safe to exercise while taking Lusutrombopag?
You can exercise while taking Lusutrombopag, but be cautious. This medication can increase the risk of bleeding, which might affect your ability to engage in certain activities. Avoid high-impact sports or activities that could lead to injury. Listen to your body and stop exercising if you feel dizzy or experience unusual symptoms. Consult your doctor for personalized advice.
Is it safe to stop Lusutrombopag?
It's important not to stop Lusutrombopag suddenly without consulting your doctor. Stopping this medication abruptly can affect your health condition. Your doctor might suggest gradually reducing your dose or switching to a different medication to keep your condition under control. Always talk with your doctor before making any changes to your medication regimen.
Is Lusutrombopag addictive?
Lusutrombopag is not addictive or habit-forming. This medication doesn't cause dependency or withdrawal symptoms when you stop taking it. You won't experience cravings for this medication or feel compelled to take more than prescribed. If you have concerns about medication dependence, you can feel confident that Lusutrombopag doesn't carry this risk while managing your health condition.
Is Lusutrombopag safe for the elderly?
Elderly patients may be more vulnerable to the side effects of Lusutrombopag, such as an increased risk of bleeding. It's important for older adults to be closely monitored by their healthcare provider while taking this medication. Your doctor will consider your overall health and any other medications you take to ensure Lusutrombopag is safe for you.
What are the most common side effects of Lusutrombopag?
Side effects are unwanted reactions that can happen when taking a medication. With Lusutrombopag, common side effects include headache and nausea. These effects vary from person to person. If you notice new symptoms after starting Lusutrombopag, they might be temporary or unrelated to the medication. Talk with your doctor before stopping any medication.
Who should avoid taking Lusutrombopag?
Lusutrombopag should not be used if you have a known allergy to it or its ingredients. Serious allergic reactions, which cause rash, hives, or swelling that makes breathing difficult, require immediate medical help. Always consult your doctor about any concerns or conditions that might affect your use of Lusutrombopag.
