Lorazepam

Partial Epilepsies, Depressive Disorder ... show more

Drug Status

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Government Approvals

US(FDA), UK(BNF)

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WHO Essential Medicine

YES

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Known Teratogen

NO

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Pharmaceutical Class

Benzodiazepine

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Controlled Drug Substance

YES

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Drug Ingredient

Lorazepam

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Summary

  • Lorazepam is used to treat conditions such as anxiety, insomnia, and seizures. It helps calm the brain and nervous system, providing quick relief from severe anxiety. However, it's not intended for everyday worries or long-term use.

  • Lorazepam works by attaching to special spots on brain cells called GABA receptors. This makes those brain cells less active, leading to a calming effect. It's like turning down the volume on a noisy brain. This results in reduced anxiety, better sleep, or cessation of seizures.

  • For anxiety, the typical dose is 2-3 mg daily in divided doses. For insomnia, a single dose of 2-4 mg at bedtime may be prescribed. The medicine can be taken with or without food. It should not be crushed or chewed, but swallowed whole.

  • Common side effects of Lorazepam include drowsiness, dizziness, weakness, and feeling unsteady. In rare cases, it may cause mood swings, irritability, depression, and decreased libido. It may also cause sleepiness and dizziness, making it harder to sleep well or drive.

  • Lorazepam is a strong medicine with serious risks. Mixing it with opioids can be deadly. It makes you sleepy and dizzy, so don't drive or use machinery. It's addictive and stopping it suddenly can be very dangerous. It can also make depression worse. Avoid alcohol and be cautious with caffeine and exercise.

Indications and Purpose

Directions for Use

Warnings and Precautions