Lorazepam
Partial Epilepsies, Depressive Disorder ... show more
.svg)
Drug Status
Government Approvals
US(FDA), UK(BNF)
WHO Essential Medicine
YES
Known Teratogen
No
Pharmaceutical Class
Benzodiazepine
Controlled Drug Substance
YES
Lorazepam
Summary
Lorazepam is used to treat conditions such as anxiety, insomnia, and seizures. It helps calm the brain and nervous system, providing quick relief from severe anxiety. However, it's not intended for everyday worries or long-term use.
Lorazepam works by attaching to special spots on brain cells called GABA receptors. This makes those brain cells less active, leading to a calming effect. It's like turning down the volume on a noisy brain. This results in reduced anxiety, better sleep, or cessation of seizures.
For anxiety, the typical dose is 2-3 mg daily in divided doses. For insomnia, a single dose of 2-4 mg at bedtime may be prescribed. The medicine can be taken with or without food. It should not be crushed or chewed, but swallowed whole.
Common side effects of Lorazepam include drowsiness, dizziness, weakness, and feeling unsteady. In rare cases, it may cause mood swings, irritability, depression, and decreased libido. It may also cause sleepiness and dizziness, making it harder to sleep well or drive.
Lorazepam is a strong medicine with serious risks. Mixing it with opioids can be deadly. It makes you sleepy and dizzy, so don't drive or use machinery. It's addictive and stopping it suddenly can be very dangerous. It can also make depression worse. Avoid alcohol and be cautious with caffeine and exercise.
Indications and Purpose
How does Lorazepam work?
Lorazepam works by enhancing the effects of a neurotransmitter called GABA, which is a chemical in the brain that helps calm nerve activity. Think of it like turning down the volume on a loud radio. By increasing GABA's calming effects, Lorazepam helps reduce anxiety and promote relaxation. This makes it effective for treating anxiety disorders and insomnia, which is difficulty sleeping. Always follow your doctor's instructions and discuss any concerns about how Lorazepam works with your healthcare provider.
Is Lorazepam effective?
Yes, Lorazepam is effective for treating anxiety and insomnia, which is difficulty sleeping. It works by calming the brain and nerves, providing relief from anxiety symptoms and helping with sleep. Clinical studies support its effectiveness for these conditions. However, Lorazepam is usually prescribed for short-term use due to the risk of dependence. Always follow your doctor's instructions and discuss any concerns about its effectiveness with your healthcare provider. They can help ensure Lorazepam is working well for your needs.
What is Lorazepam?
Lorazepam is a medication that belongs to the benzodiazepine class. It works by calming the brain and nerves, providing relief from anxiety and helping with sleep. Lorazepam is primarily used to treat anxiety disorders and insomnia, which is difficulty sleeping. It may also be used for other conditions as determined by your doctor. Lorazepam is usually prescribed for short-term use due to the risk of dependence. Always follow your doctor's instructions and discuss any concerns about its use with your healthcare provider.
Directions for Use
For how long do I take Lorazepam?
Lorazepam is usually prescribed for short-term use, typically 2 to 4 weeks, for conditions like anxiety or insomnia. It's not recommended for long-term use due to the risk of dependence. Your doctor will determine the appropriate duration based on your specific needs and response to treatment. Always follow your doctor's instructions and do not change your dosage or duration without consulting them. If you have concerns about how long to take Lorazepam, discuss them with your healthcare provider.
How do I dispose of Lorazepam?
To dispose of Lorazepam, take it to a drug take-back program or collection site at a pharmacy or hospital. They will dispose of it properly to prevent harm to people or the environment. If you can't find a take-back program, you can throw Lorazepam in the trash at home. First, mix it with something undesirable, like used coffee grounds, seal it in a plastic bag, and throw it away. Always keep medications out of reach of children and pets.
How do I take Lorazepam?
Take Lorazepam exactly as your doctor prescribes. It's usually taken 2 to 3 times a day, with or without food. Swallow the tablet whole; do not crush or chew it. If you miss a dose, take it as soon as you remember unless it's almost time for your next dose. In that case, skip the missed dose and continue your regular schedule. Do not double up on doses. Avoid alcohol while taking Lorazepam, as it can increase side effects. Always follow your doctor's specific instructions regarding dosage and any dietary restrictions.
How long does it take for Lorazepam to start working?
Lorazepam starts working quickly, usually within 20 to 30 minutes after taking it. The full therapeutic effect can be felt within 1 to 2 hours. Individual factors, like your metabolism and overall health, can affect how quickly you feel the effects. Always take Lorazepam exactly as prescribed for the best results. If you have concerns about how long it takes to work, discuss them with your doctor. They can provide personalized advice based on your health needs.
How should I store Lorazepam?
Store Lorazepam at room temperature, away from light and moisture. Keep it in a tightly closed container to protect it from damage. Avoid storing it in humid places like bathrooms, as moisture can affect its effectiveness. Always keep Lorazepam out of reach of children and pets to prevent accidental ingestion. Check the expiration date regularly and properly dispose of any unused or expired medication. If you have questions about storing Lorazepam, ask your pharmacist or healthcare provider for guidance.
What is the usual dose of Lorazepam?
The usual starting dose of Lorazepam for adults is 2 to 3 mg per day, divided into 2 or 3 doses. Your doctor may adjust your dose based on your response and needs. The maximum recommended dose is 10 mg per day. For elderly patients, the dose is usually lower to reduce the risk of side effects. Always follow your doctor's specific dosing instructions for your personal health needs. Do not change your dose without consulting your healthcare provider.
Warnings and Precautions
Can I take Lorazepam with other prescription drugs?
Lorazepam can interact with other medications, increasing the risk of side effects. Combining it with other central nervous system depressants, like opioids or alcohol, can enhance drowsiness and respiratory depression, which is slowed breathing. Some medications, like certain antidepressants, can also increase Lorazepam's effects. Always inform your doctor about all medications you're taking to avoid interactions. They can help ensure your treatment is safe and effective. Regularly review your medication list with your healthcare provider to prevent potential issues.
Can Lorazepam be taken safely while breastfeeding?
Lorazepam is not recommended while breastfeeding. It can pass into breast milk and may affect the nursing baby, causing drowsiness or feeding difficulties. If you're taking Lorazepam and want to breastfeed, talk with your doctor about safer medication options. They can help you find a treatment that allows you to nurse your baby safely. Always inform your healthcare provider if you're breastfeeding or planning to breastfeed while taking Lorazepam.
Can Lorazepam be taken safely while pregnant?
Lorazepam is not recommended during pregnancy, especially in the first trimester. It may harm the unborn baby, causing birth defects or withdrawal symptoms after birth. If you're pregnant or planning to become pregnant, talk with your doctor about the safest way to manage your condition. They can help create a treatment plan that protects both you and your baby. Always inform your healthcare provider if you become pregnant while taking Lorazepam.
Does Lorazepam have adverse effects?
Yes, Lorazepam can have adverse effects, which are unwanted reactions to the medication. Common adverse effects include drowsiness, dizziness, and weakness. These effects are usually mild and may go away as your body adjusts. Serious side effects, like confusion, mood changes, or difficulty breathing, require immediate medical attention. If you experience any new or worsening symptoms, contact your doctor. They can help determine if Lorazepam is the cause and suggest appropriate actions. Always report any concerning symptoms to your healthcare provider.
Does Lorazepam have any safety warnings?
Yes, Lorazepam has important safety warnings. It can cause drowsiness, which may impair your ability to drive or operate machinery. Avoid alcohol, as it can increase drowsiness and other side effects. Lorazepam can be habit-forming, so use it only as prescribed. Stopping Lorazepam suddenly can cause withdrawal symptoms, so consult your doctor before making any changes. If you experience unusual mood changes, confusion, or difficulty breathing, seek medical help immediately. Always follow your doctor's advice and report any concerning symptoms.
Is it safe to drink alcohol while taking Lorazepam?
No, it's best to avoid alcohol while taking Lorazepam. Alcohol can increase the sedative effects of Lorazepam, leading to increased drowsiness, dizziness, and difficulty concentrating. This combination can be dangerous and impair your ability to perform tasks that require alertness, like driving. If you do choose to drink, limit your alcohol intake and be aware of how it affects you. Always talk with your doctor about alcohol use while taking Lorazepam to get personalized advice based on your health situation.
Is it safe to exercise while taking Lorazepam?
Yes, you can exercise while taking Lorazepam, but be cautious. Lorazepam can cause drowsiness and dizziness, which might affect your balance and coordination during physical activity. Start with light exercises and see how your body responds. Avoid strenuous activities or high-impact sports until you know how Lorazepam affects you. Stay hydrated and listen to your body. If you feel dizzy or lightheaded, stop exercising and rest. Always talk with your doctor about your exercise routine while taking Lorazepam.
Is it safe to stop Lorazepam?
No, it's not safe to stop Lorazepam suddenly. Doing so can cause withdrawal symptoms, which may include anxiety, insomnia, and irritability. Lorazepam is usually used for short-term relief of anxiety or insomnia. If you need to stop taking it, your doctor will guide you on how to gradually reduce your dose to minimize withdrawal effects. Always consult your healthcare provider before making any changes to your medication. They can help you stop Lorazepam safely and manage any withdrawal symptoms.
Is Lorazepam addictive?
Yes, Lorazepam can be addictive. It has the potential to cause physical and psychological dependence, especially with long-term use. Signs of dependence include needing higher doses to achieve the same effect and experiencing withdrawal symptoms when not taking the medication. To prevent dependence, use Lorazepam exactly as prescribed by your doctor. Do not increase your dose or take it more frequently than directed. If you have concerns about dependence, discuss them with your healthcare provider. They can help you manage your medication safely.
Is Lorazepam safe for the elderly?
Lorazepam can be used by the elderly, but with caution. Older adults are more sensitive to its effects, which can increase the risk of drowsiness, dizziness, and falls. Lower doses are usually recommended to minimize these risks. Regular monitoring by a healthcare provider is important to ensure safety and effectiveness. If you're an older adult taking Lorazepam, report any unusual symptoms to your doctor. They can help adjust your treatment to suit your needs and reduce potential risks.
What are the most common side effects of Lorazepam?
Common side effects of Lorazepam include drowsiness, dizziness, and weakness. These side effects are usually mild and may decrease as your body adjusts to the medication. If you experience these symptoms, avoid activities that require alertness, like driving, until you know how Lorazepam affects you. If side effects persist or worsen, talk with your doctor. They can help determine if Lorazepam is the cause and suggest ways to manage these effects. Always report any new or concerning symptoms to your healthcare provider.
Who should avoid taking Lorazepam?
Lorazepam should not be used if you have severe respiratory problems, which affect your breathing, or if you have a known allergy to it. It's also contraindicated in people with acute narrow-angle glaucoma, which is a type of eye condition. Use caution if you have a history of substance abuse, as Lorazepam can be habit-forming. Always inform your doctor about your medical history before starting Lorazepam. They can help determine if it's safe for you and discuss any potential risks.
Forms / Brands
