Loratadine
Perennial Allergic Rhinitis, Urticaria
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Drug Status
Government Approvals
US(FDA), UK(BNF)
WHO Essential Medicine
YES
Known Teratogen
NO
Pharmaceutical Class
Histamine-1 Receptor Antagonist
Controlled Drug Substance
No
Loratadine
Summary
Loratadine is used to treat allergies such as hay fever, hives, and other allergic reactions. It helps relieve symptoms like sneezing, runny nose, itchy eyes and skin rashes caused by allergens like pollen, dust, pet dander, and insect bites.
Loratadine is an antihistamine. It works by blocking histamine, a chemical in the body that is released during an allergic reaction and causes symptoms like sneezing, itching and inflammation.
For adults and children over 12 years, the usual dose is 10 mg once daily. For children aged 2-12 years, the dose depends on weight. Those under 30 kg take 5 mg once daily, and those over 30 kg take 10 mg once daily.
Common side effects include headache, dry mouth, and rare instances of drowsiness. Less common effects are stomach upset, fast heartbeat, or liver problems in rare cases.
People with severe liver disease, those allergic to Loratadine, pregnant or breastfeeding women, and children under 2 years old should avoid Loratadine. If you have kidney or liver issues, take Loratadine under medical supervision.
Indications and Purpose
How does Loratadine work?
Loratadine is an antihistamine that works by blocking histamine, which is a substance in the body that causes allergy symptoms. Think of it like a shield that prevents histamine from attaching to its receptors, reducing symptoms like sneezing, runny nose, and itchy eyes. This action helps relieve allergy symptoms and makes Loratadine effective for treating seasonal allergies and hives. It's important to take Loratadine as directed to achieve the best results.
Is Loratadine effective?
Loratadine is effective for relieving allergy symptoms like sneezing, runny nose, and itchy eyes. It works by blocking histamine, which is a substance in the body that causes allergy symptoms. Clinical studies show that Loratadine significantly reduces these symptoms in people with seasonal allergies. It's important to take Loratadine as directed to achieve the best results. If you don't notice improvement, talk with your doctor about other treatment options.
What is Loratadine?
Loratadine is an antihistamine used to relieve allergy symptoms like sneezing, runny nose, and itchy eyes. It works by blocking histamine, which is a substance in the body that causes allergy symptoms. Loratadine is commonly used for seasonal allergies and can also help with hives. It's usually taken once daily and is available over-the-counter. Always follow your doctor's advice on how to use Loratadine for your specific health needs.
Directions for Use
For how long do I take Loratadine?
Loratadine is usually taken for short-term relief of allergy symptoms. You can take it daily as long as you have symptoms. If your symptoms improve, you can stop taking it. Always follow your doctor's advice on how long to take Loratadine, especially if you have ongoing allergy issues. Your doctor can provide guidance based on your specific health needs.
How do I dispose of Loratadine?
To dispose of Loratadine, take it to a drug take-back program or collection site at a pharmacy or hospital. If that's not possible, you can throw it in the trash at home. First, remove it from its original container, mix it with something undesirable like used coffee grounds, seal the mixture in a plastic bag, and throw it away. This helps prevent accidental ingestion by children or pets.
How do I take Loratadine?
Take Loratadine once daily, usually in the morning. You can take it with or without food. If you have trouble swallowing pills, Loratadine can be crushed or mixed with water or food. If you miss a dose, take it as soon as you remember, unless it's almost time for your next dose. In that case, skip the missed dose and continue your regular schedule. Don't take two doses at once. There are no specific food or beverage restrictions while taking Loratadine, but always follow your doctor's advice.
How long does it take for Loratadine to start working?
Loratadine starts working within 1 to 3 hours after you take it. Most people notice relief from allergy symptoms within this time frame. The full effect of Loratadine can be felt within a few hours. Individual factors like age, weight, and overall health can affect how quickly it works. Take Loratadine as directed for the best results. If you don't notice improvement, talk with your doctor.
How should I store Loratadine?
Store Loratadine at room temperature, away from moisture and light. Keep it in a tightly closed container to protect it from damage. Avoid storing it in humid places like bathrooms, as moisture can affect its effectiveness. Always keep Loratadine out of reach of children to prevent accidental ingestion. Check the expiration date regularly and dispose of any unused or expired medication properly.
What is the usual dose of Loratadine?
The usual dose of Loratadine for adults and children over 6 years old is 10 mg once daily. This dose can be taken with or without food. For children aged 2 to 5 years, the dose is typically 5 mg once daily. Always follow your doctor's specific dosing instructions, especially for children or the elderly, as they may require adjustments based on their health needs.
Warnings and Precautions
Can I take Loratadine with other prescription drugs?
Loratadine has few significant drug interactions. However, taking it with other medications that cause drowsiness, like certain antihistamines or sedatives, can increase this effect. Always inform your doctor about all medications you're taking to avoid potential interactions. They can help determine if Loratadine is safe to use with your current medications and suggest alternatives if needed.
Can Loratadine be taken safely while breastfeeding?
Loratadine is considered safe to use while breastfeeding. It passes into breast milk in small amounts, but it's unlikely to harm a nursing infant. However, it's always best to consult your doctor before taking any medication while breastfeeding. They can provide personalized advice based on your health needs and ensure the safety of your baby.
Can Loratadine be taken safely while pregnant?
Loratadine is generally considered safe during pregnancy, but it's important to consult your doctor before using it. Limited studies in pregnant women suggest that Loratadine doesn't increase the risk of birth defects. However, your doctor will weigh the benefits and risks based on your specific situation. Always follow your doctor's advice on medication use during pregnancy to ensure the safety of both you and your baby.
Does Loratadine have adverse effects?
Adverse effects are unwanted reactions to a medication. Loratadine is generally well-tolerated, but some people may experience mild side effects like headache, drowsiness, or dry mouth. These effects are usually temporary. Serious adverse effects are rare but can include allergic reactions like rash or swelling. If you notice any new or worsening symptoms, contact your doctor. They can help determine if these symptoms are related to Loratadine and suggest appropriate actions.
Does Loratadine have any safety warnings?
Loratadine is generally safe, but there are a few safety warnings. It should not be used if you are allergic to it or any of its ingredients. If you experience symptoms like rash, itching, or swelling, seek medical help immediately. Loratadine can cause drowsiness in some people, so be cautious when driving or operating machinery. Always follow your doctor's instructions and inform them of any other medications you are taking to avoid interactions.
Is it safe to drink alcohol while taking Loratadine?
It's best to avoid alcohol while taking Loratadine. Alcohol can increase the risk of drowsiness, which is a possible side effect of Loratadine. This combination might make you feel more tired or less alert. If you choose to drink, do so in moderation and be aware of how your body responds. Talk with your doctor about alcohol use while taking Loratadine for personalized advice.
Is it safe to exercise while taking Loratadine?
It's safe to exercise while taking Loratadine. This medication doesn't typically affect exercise capacity. However, Loratadine can cause mild drowsiness in some people. If you feel unusually tired or dizzy during exercise, take a break and rest. Stay hydrated and listen to your body. If you have concerns about exercising while taking Loratadine, talk with your doctor for personalized advice.
Is it safe to stop Loratadine?
Loratadine is often used for temporary relief of allergy symptoms. You can stop taking it when your symptoms improve. There are no withdrawal symptoms associated with stopping Loratadine. However, if you stop taking it too soon, your allergy symptoms might return. Always follow your doctor's advice on how long to take Loratadine, especially if you have ongoing allergy issues.
Is Loratadine addictive?
Loratadine is not addictive or habit-forming. It doesn't cause dependency or withdrawal symptoms when you stop taking it. Loratadine works by blocking histamine, which is a substance in the body that causes allergy symptoms. This mechanism doesn't affect brain chemistry in ways that could lead to addiction. You won't experience cravings for this medication or feel compelled to take more than prescribed.
Is Loratadine safe for the elderly?
Loratadine is generally safe for the elderly, but they may be more sensitive to its effects, such as drowsiness. Older adults should use Loratadine with caution and under a doctor's guidance. It's important to monitor for any side effects and report them to a healthcare provider. Dose adjustments may be necessary based on individual health needs and other medications being taken.
What are the most common side effects of Loratadine?
Side effects are unwanted reactions to a medication. Common side effects of Loratadine include headache, drowsiness, and dry mouth. These effects are usually mild and temporary. If you experience new symptoms after starting Loratadine, they might be unrelated to the medication. Talk with your doctor if you have concerns. They can help determine if the symptoms are related to Loratadine and advise on the best course of action.
Who should avoid taking Loratadine?
Don't take Loratadine if you're allergic to it or its ingredients. Serious allergic reactions, which cause rash, hives, or swelling that makes breathing difficult, require immediate medical help. Loratadine should be used with caution in people with liver or kidney problems, as they may need dose adjustments. Always consult your doctor about these concerns and inform them of any other medications you are taking to avoid interactions.
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