Ibuprofen

Juvenile Arthritis, Postoperative Pain ... show more

Drug Status

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Government Approvals

US(FDA), UK(BNF)

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WHO Essential Medicine

YES

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Known Teratogen

NO

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Pharmaceutical Class

Nonsteroidal Anti-inflammatory Drug

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Controlled Drug Substance

NO

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Drug Ingredient

Ibuprofen

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Summary

  • Ibuprofen is used to treat various conditions such as headaches, muscle pain, toothaches, menstrual cramps, minor injuries, arthritis, tendonitis, and other inflammatory conditions. It's also used to reduce fever caused by infections or other conditions.

  • Ibuprofen works by inhibiting enzymes called cyclooxygenase (COX) which are responsible for producing chemicals called prostaglandins that cause inflammation, pain, and fever. By blocking these enzymes, ibuprofen reduces these symptoms.

  • For adults, the usual dosage of ibuprofen is 200 to 400 mg every 4 to 6 hours as needed. The maximum daily dose is 1200 mg for over-the-counter use and up to 2400 mg for prescription use. It's taken orally, ideally with food or milk to reduce stomach irritation.

  • Common side effects of ibuprofen include stomach upset, nausea, dizziness, and headache. More serious effects can include gastrointestinal bleeding, ulcers, kidney damage, and increased risk of heart attack or stroke with long-term use. Allergic reactions such as skin rashes or swelling are also possible.

  • Ibuprofen should not be used by individuals with a history of gastrointestinal bleeding, ulcers, severe kidney or liver disease, or heart conditions such as heart failure. It's also not recommended for pregnant individuals, especially in the third trimester. Caution is advised for people with high blood pressure, asthma, or a history of allergic reactions to NSAIDs.

Indications and Purpose

Directions for Use

Warnings and Precautions