Flurbiprofen
Macular Edema, Rheumatoid Arthritis ... show more
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Drug Status
Government Approvals
US(FDA), UK(BNF)
WHO Essential Medicine
NO
Known Teratogen
NO
Pharmaceutical Class
Nonsteroidal Anti-inflammatory Drug
Controlled Drug Substance
NO
Flurbiprofen
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Click HereSummary
Flurbiprofen is used to relieve pain, swelling, and stiffness caused by conditions such as osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis, a type of arthritis that mainly affects the spine.
Flurbiprofen works by inhibiting enzymes called COX1 and COX2. These enzymes are involved in the production of substances called prostaglandins, which cause inflammation, pain, and fever. By reducing their production, Flurbiprofen helps alleviate these symptoms.
The usual daily dose of Flurbiprofen for adults is 200 to 300 mg, divided into two, three, or four doses. The largest recommended single dose is 100 mg. It's taken by mouth, usually two to four times a day, with or without food. It's not recommended for use in children under 12 years of age.
Common side effects of Flurbiprofen include headache, nausea, vomiting, diarrhea, and dizziness. Serious adverse effects can include cardiovascular events, gastrointestinal bleeding, and liver or kidney issues.
Flurbiprofen carries a risk of serious cardiovascular events like heart attack and stroke, and gastrointestinal issues like bleeding and ulcers. It's contraindicated in patients with a history of allergic reactions to NSAIDs, recent heart surgery, or severe heart, liver, or kidney failure.
Indications and Purpose
How does Flurbiprofen work?
Flurbiprofen works by inhibiting the enzymes COX-1 and COX-2, which are involved in the production of prostaglandins. Prostaglandins are substances in the body that cause inflammation, pain, and fever. By reducing their production, Flurbiprofen helps alleviate these symptoms.
How does one know if Flurbiprofen is working?
The benefit of Flurbiprofen is evaluated by monitoring the relief of symptoms such as pain, swelling, and stiffness. Regular check-ups with your doctor and laboratory tests may be conducted to assess your body's response and adjust the dosage if necessary.
Is Flurbiprofen effective?
Flurbiprofen is effective in relieving pain, tenderness, swelling, and stiffness caused by osteoarthritis and rheumatoid arthritis. It works by inhibiting the production of substances in the body that cause inflammation and pain. Clinical trials and patient reports support its effectiveness for these conditions.
What is Flurbiprofen?
Flurbiprofen is used to relieve pain, swelling, and stiffness caused by osteoarthritis and rheumatoid arthritis. It belongs to a class of medications called NSAIDs, which work by inhibiting the production of substances in the body that cause inflammation and pain. It is also used for ankylosing spondylitis.
What is Flurbiprofen used for?
Flurbiprofen is indicated for the relief of pain, tenderness, swelling, and stiffness caused by osteoarthritis and rheumatoid arthritis. It is also used to treat ankylosing spondylitis, a type of arthritis that mainly affects the spine. Always consult your doctor for appropriate use.
Directions for Use
For how long do I take Flurbiprofen?
Flurbiprofen should be used for the shortest duration necessary to relieve symptoms. The exact duration depends on the condition being treated and the patient's response to the medication. Always follow your doctor's instructions regarding the length of treatment.
How do I take Flurbiprofen?
Flurbiprofen should be taken by mouth, usually two to four times a day, with or without food. Taking it with food may help reduce stomach upset. Follow your doctor's instructions and avoid alcohol to minimize gastrointestinal risks.
How long does it take for Flurbiprofen to start working?
Flurbiprofen typically begins to relieve pain and inflammation within a few hours of taking a dose. However, the full effect may take longer, depending on the condition being treated and individual response.
How should I store Flurbiprofen?
Store Flurbiprofen in its original container, tightly closed, at room temperature away from excess heat and moisture. Keep it out of reach of children and pets. Do not store it in the bathroom. Dispose of unneeded medication through a take-back program.
What is the usual dose of Flurbiprofen?
For adults, the usual daily dose of Flurbiprofen is 200 to 300 mg, divided into two, three, or four doses. The largest recommended single dose is 100 mg. Flurbiprofen is not recommended for use in children under 12 years of age. Always follow your doctor's advice for the correct dosage.
Warnings and Precautions
Can Flurbiprofen be taken safely while breastfeeding?
Flurbiprofen is poorly excreted into human milk, but caution is advised. The benefits of breastfeeding should be weighed against the mother's need for Flurbiprofen and any potential effects on the infant. Consult your doctor for personalized advice.
Can Flurbiprofen be taken safely while pregnant?
Flurbiprofen is not recommended during pregnancy, especially after 20 weeks, due to risks of fetal harm such as premature closure of the ductus arteriosus and renal dysfunction. If necessary, use the lowest effective dose for the shortest duration. Consult your doctor for personalized advice.
Can I take Flurbiprofen with other prescription drugs?
Flurbiprofen can interact with anticoagulants, other NSAIDs, SSRIs, SNRIs, and corticosteroids, increasing the risk of bleeding. It may also affect the efficacy of ACE inhibitors, ARBs, and diuretics. Always inform your doctor about all medications you are taking to avoid harmful interactions.
Is Flurbiprofen safe for the elderly?
Elderly patients are at greater risk for serious cardiovascular, gastrointestinal, and renal adverse reactions when using Flurbiprofen. It is recommended to start with the lowest effective dose and monitor for adverse effects. Regular check-ups with a healthcare provider are advised to ensure safe use.
Is it safe to drink alcohol while taking Flurbiprofen?
Drinking alcohol while taking Flurbiprofen can increase the risk of gastrointestinal bleeding, ulcers, or holes in the stomach or intestine. It is advisable to avoid alcohol or consume it in moderation and consult your doctor for personalized advice.
Is it safe to exercise while taking Flurbiprofen?
Flurbiprofen does not inherently limit the ability to exercise. However, if you experience side effects such as dizziness, fatigue, or shortness of breath, it may affect your ability to exercise safely. Consult your doctor if you experience these symptoms.
Who should avoid taking Flurbiprofen?
Flurbiprofen carries a risk of serious cardiovascular events, such as heart attack and stroke, and gastrointestinal issues like bleeding and ulcers. It is contraindicated in patients with a history of allergic reactions to NSAIDs, recent heart surgery, or severe heart, liver, or kidney failure. Always consult your doctor before use.
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