Flurazepam
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Drug Status
Government Approvals
US(FDA), UK(BNF)
WHO Essential Medicine
NO
Known Teratogen
NO
Pharmaceutical Class
Benzodiazepine
Controlled Drug Substance
NO
Flurazepam
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Click HereSummary
Flurazepam is used to treat insomnia, specifically for difficulty falling asleep, frequent nocturnal awakenings, and early morning awakenings. It helps improve sleep quality and duration in individuals experiencing sleep disturbances.
Flurazepam works by binding to specific receptors in the brain, enhancing the effects of a neurotransmitter called GABA. This action slows down brain activity, promoting relaxation and sleep.
Flurazepam is typically taken by mouth, usually at bedtime. The usual dose for adults is 15 mg, which can be increased to 30 mg if necessary. For elderly or debilitated patients, the dose should not exceed 15 mg.
Common side effects of Flurazepam include drowsiness, dizziness, and lightheadedness. Serious adverse effects can include respiratory depression, coma, and allergic reactions like swelling and difficulty breathing.
Flurazepam should not be used with opioids, alcohol, or other CNS depressants due to the risk of severe sedation and respiratory depression. It is not recommended during pregnancy, breastfeeding, or for use in children. It's also contraindicated for patients with severe respiratory insufficiency and sleep apnea.
Indications and Purpose
How does Flurazepam work?
Flurazepam works by binding to specific receptors in the brain, enhancing the effects of a neurotransmitter called GABA. This action slows down brain activity, promoting relaxation and sleep.
How does one know if Flurazepam is working?
The benefit of Flurazepam is evaluated by monitoring improvements in sleep quality and duration. If insomnia symptoms do not improve within 7 to 10 days, or if they worsen, consult your doctor. They may reassess your treatment plan or explore underlying conditions.
Is Flurazepam effective?
Flurazepam is effective in treating insomnia by helping individuals fall asleep and stay asleep. Sleep laboratory studies have shown its effectiveness for at least 28 consecutive nights. It works by slowing brain activity, allowing for better sleep quality.
What is Flurazepam?
Flurazepam is used to treat insomnia by helping individuals fall asleep and stay asleep. It belongs to the benzodiazepine class and works by slowing brain activity, promoting relaxation and sleep. It is typically used for short-term treatment due to the risk of dependence and side effects.
What is Flurazepam used for?
Flurazepam is indicated for the treatment of insomnia, specifically for difficulty falling asleep, frequent nocturnal awakenings, and early morning awakenings. It is used to improve sleep quality and duration in individuals experiencing sleep disturbances.
Directions for Use
For how long do I take Flurazepam?
Flurazepam is typically used for short-term treatment of insomnia, usually for a few days to two weeks, with a maximum of four weeks including the tapering off process. Prolonged use is not recommended without re-evaluation of the patient's condition.
How do I take Flurazepam?
Flurazepam should be taken by mouth, usually at bedtime, as directed by your doctor. It can be taken with or without food. There are no specific food restrictions, but avoid alcohol and other CNS depressants while taking this medication.
How long does it take for Flurazepam to start working?
Flurazepam starts working slowly and may take a few nights to reach its full effect. You may notice improvements in sleep quality on the second or third night after starting the medication.
How should I store Flurazepam?
Store Flurazepam in a tightly closed container at room temperature, away from light, heat, and moisture. Keep it out of reach of children and pets. Do not store it in the bathroom to prevent exposure to humidity.
What is the usual dose of Flurazepam?
For adults, the usual dose of Flurazepam is 15 mg, which can be increased to 30 mg if necessary. For elderly or debilitated patients, the dose should not exceed 15 mg due to increased sensitivity. Flurazepam is not recommended for use in children.
Warnings and Precautions
Can Flurazepam be taken safely while breastfeeding?
Breastfeeding is not recommended while taking Flurazepam due to the potential for serious adverse reactions in infants, including sedation and withdrawal symptoms. Consult your doctor for advice on alternative treatments or feeding options.
Can Flurazepam be taken safely while pregnant?
Flurazepam is not recommended during pregnancy, especially in the late stages, due to the risk of neonatal sedation and withdrawal symptoms. There is a pregnancy registry for monitoring outcomes, but consult your doctor for personalized advice if you are pregnant or planning to become pregnant.
Can I take Flurazepam with other prescription drugs?
Flurazepam interacts with opioids, other benzodiazepines, alcohol, and CNS depressants, increasing the risk of severe sedation and respiratory depression. It may also interact with certain allergy medications and other drugs affecting the central nervous system. Always inform your doctor of all medications you are taking.
Is Flurazepam safe for the elderly?
Elderly patients are more sensitive to Flurazepam and may experience increased sedation, dizziness, and confusion. The recommended dose for elderly patients is 15 mg, and they should be monitored closely for side effects. Caution is advised to prevent falls and injuries.
Is it safe to drink alcohol while taking Flurazepam?
Drinking alcohol while taking Flurazepam is not recommended. Alcohol can increase the sedative effects of Flurazepam, leading to severe drowsiness, respiratory depression, and potentially life-threatening side effects. It is important to avoid alcohol to ensure the safe use of this medication.
Is it safe to exercise while taking Flurazepam?
Flurazepam can cause drowsiness and dizziness, which may affect your ability to exercise safely. It is important to understand how the medication affects you before engaging in physical activities. Consult your doctor if you have concerns about exercising while taking Flurazepam.
Who should avoid taking Flurazepam?
Flurazepam should not be used with opioids, alcohol, or other CNS depressants due to the risk of severe sedation and respiratory depression. It is contraindicated in patients with hypersensitivity to benzodiazepines, severe respiratory insufficiency, and sleep apnea. Caution is advised for those with a history of substance abuse or mental health disorders.
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