Everolimus

What is Everolimus used for?

Everolimus is used for:

• Treating kidney, breast, and pancreatic cancers.
• Preventing organ rejection in kidney and liver transplant patients.
• Treating certain types of brain tumors and lung diseases linked to genetic disorders.

How does Everolimus work?

Everolimus blocks the mTOR pathway, stopping cancer cells from growing and slowing tumor spread. In transplant patients, it reduces immune system activity to prevent the body from attacking the new organ.

Is Everolimus effective?

Yes, Everolimus is effective in slowing cancer growth and preventing organ rejection when taken correctly. However, it does not cure cancer but helps manage it. In transplant patients, it significantly reduces rejection risks when used with other immunosuppressants.

How does one know if Everolimus is working?

For cancer treatment, doctors check tumor size through scans and blood tests. For transplant patients, doctors monitor organ function tests and blood levels to ensure the immune system is controlled properly.

What is the usual dose of Everolimus?

The dose varies based on the condition being treated.

• For cancer treatment: Typically, 10 mg once daily.
• For transplant patients: Usually, 0.75 mg twice daily with other immunosuppressants.Doses may change based on response, blood tests, and side effects. Always follow the doctor’s prescription carefully.

How do I take Everolimus?

Take Everolimus once daily at the same time each day, with or without food. Swallow the tablet whole with water, without crushing or chewing it. Avoid grapefruit and grapefruit juice, as they can affect how the medicine works in the body.

For how long do I take Everolimus?

The duration depends on the condition:

• For cancer: As long as it remains effective and tolerated.
• For transplant patients: It is a long-term medication to prevent organ rejection.Your doctor will decide the treatment duration based on your health condition and response.

How long does it take for Everolimus to start working?

It starts working within weeks, but noticeable improvements depend on the condition. Cancer patients may take a few months to see tumor shrinkage, while transplant patients need regular monitoring to ensure the organ is not being rejected.

How should I store Everolimus?

Store Everolimus at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep it out of reach of children.

Who should avoid taking Everolimus?

People with severe liver disease, active infections, uncontrolled diabetes, or a history of severe allergic reactions to Everolimus should avoid it. Pregnant women should not use it unless absolutely necessary.

Can I take Everolimus with other prescription drugs?

Everolimus interacts with many drugs, including antibiotics, antifungals, seizure medicines, and blood pressure medications. Always inform your doctor about all the medicines you are taking.

Can I take Everolimus with vitamins or supplements?

Some supplements, like St. John’s Wort, certain herbal teas, and high doses of vitamin C, may interact with Everolimus. Always consult your doctor before taking any supplements.

Can Everolimus be taken safely while pregnant?

Everolimus is not recommended during pregnancy, as it may harm the baby. Women of childbearing age should use effective birth control during treatment and for at least 8 weeks after stopping it.

Can Everolimus be taken safely while breastfeeding?

No, Everolimus passes into breast milk and may harm the baby. Women should avoid breastfeeding while taking this medication.

Is Everolimus safe for the elderly?

Yes, but elderly patients may have a higher risk of side effects like infections, kidney problems, and lung inflammation. Doctors may monitor them closely and adjust doses if needed.

Is it safe to exercise while taking Everolimus?

Yes, but moderate exercise is recommended. Strenuous activity may worsen fatigue, dizziness, or muscle weakness, which can be side effects of Everolimus. Light activities like walking, yoga, or stretching can help maintain fitness. Listen to your body, and if you feel excessively tired, dizzy, or short of breath, stop exercising and consult your doctor.

Is it safe to drink alcohol while taking Everolimus?

Drinking alcohol while on Everolimus is not recommended, as it may increase the risk of liver damage, dizziness, and drowsiness. Alcohol can also worsen dehydration and weaken the immune system, making you more prone to infections. If you drink alcohol regularly, speak to your doctor about safe consumption limits or possible risks.