Digoxin
Low Cardiac Output, Cardiogenic Shock ... show more
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Drug Status
Government Approvals
US(FDA), UK(BNF)
WHO Essential Medicine
YES
Known Teratogen
No
Pharmaceutical Class
Cardiac Glycoside
Controlled Drug Substance
NO
Digoxin
Summary
Digoxin is used to treat heart conditions, particularly heart failure and irregular heart rhythms (arrhythmias). It can also help control the heart rate in people with a type of irregular heartbeat called atrial fibrillation.
Digoxin increases the strength of heart contractions and helps regulate the rhythm by inhibiting an enzyme that controls sodium and potassium balance in heart cells. This improves the efficiency of the heart's pumping action.
The usual dose of Digoxin for adults is 0.125-0.25 mg per day taken orally. It's usually taken as a tablet or oral liquid. Always follow your healthcare provider's instructions for the correct dose based on your specific condition.
Common side effects of Digoxin include nausea, dizziness, blurred vision, and confusion. Serious side effects may include arrhythmias and toxicity, especially if blood levels of Digoxin become too high.
People with severe kidney disease, irregular heart rhythms, or electrolyte imbalances should avoid taking Digoxin unless recommended by a healthcare provider. Pregnant women should consult their doctor before use. Digoxin can interact with several medications and supplements, so always inform your healthcare provider about other medications you're taking.
Indications and Purpose
How does Digoxin work?
Digoxin increases the strength of heart contractions and helps regulate the rhythm by inhibiting an enzyme that controls sodium and potassium balance in heart cells. This improves the efficiency of the heart's pumping action.
Is Digoxin effective?
Yes, digoxin is effective in treating heart failure and certain arrhythmias. It helps improve heart function and reduces symptoms, such as shortness of breath and fatigue, leading to better quality of life.
What is Digoxin?
Digoxin is a medication used to treat heart conditions, particularly heart failure and irregular heart rhythms (arrhythmias). It works by increasing the force of the heart's contractions and helping to control the rhythm of the heart, making it more efficient in pumping blood.
Directions for Use
For how long do I take Digoxin?
The duration of digoxin treatment depends on the condition you're treating. It may be taken long-term for heart failure or arrhythmias, while short-term use may be prescribed for acute conditions. Your doctor will guide you on the appropriate duration.
How do I take Digoxin?
Take digoxin with or without food, as directed by your healthcare provider. It's usually taken as a tablet or oral liquid. Ensure you do not skip doses and take it at the same time each day.
How long does it take for Digoxin to start working?
Digoxin starts working within a few hours to a couple of days. However, its full effect on heart function may take several days to weeks, especially in cases of heart failure.
How should I store Digoxin?
Keep the medicine in a cool place, between 68° to 77°F (20° to 25°C), away from sunlight.
What is the usual dose of Digoxin?
The usual dose of digoxin for adults is 0.125–0.25 mg per day, taken orally. Children and elderly individuals may require adjusted doses. Always follow your healthcare provider's instructions for the correct dose based on your specific condition.
Warnings and Precautions
Can Digoxin be taken safely while breastfeeding?
Digoxin levels in breast milk are similar to the mother's blood levels. However, the amount of digoxin that reaches the baby through breast milk is much lower than the usual dose given to babies. This means that digoxin in breast milk usually won't cause any side effects in the baby. However, it's still important to be cautious and talk to a doctor before giving digoxin to a nursing mother.
Can Digoxin be taken safely while pregnant?
Digoxin is classified as a Category C drug during pregnancy, meaning it should only be used if clearly needed and prescribed by your doctor. Risks to the fetus are not well established, so it's essential to discuss alternatives with your doctor.
Can I take Digoxin with other prescription drugs?
Digoxin can interact with several medications, including diuretics, ACE inhibitors, and certain antibiotics, which can either increase digoxin levels or reduce its effectiveness. Always tell your healthcare provider about other medications you're taking.
Is Digoxin safe for the elderly?
For older adults, the amount of digoxin needed should take into account their kidney function. Monitoring their kidney function can be helpful. Older adults are more likely to have decreased kidney function, which increases the risk of harmful effects from digoxin. Those with impaired kidney function need lower maintenance doses to avoid toxicity that lasts a long time.
Is it safe to drink alcohol while taking Digoxin?
Drinking alcohol in moderation may not affect digoxin significantly, but alcohol can worsen heart conditions and increase the risk of side effects, including dizziness or fainting. Limit alcohol intake and talk to your healthcare provider.
Is it safe to exercise while taking Digoxin?
Exercise is generally safe when taking digoxin, but excessive physical strain can affect your heart function. Always consult your healthcare provider to ensure a safe level of exercise, especially if you have underlying heart conditions.
Who should avoid taking Digoxin?
People with certain conditions, like severe kidney disease, irregular heart rhythms, or electrolyte imbalances (especially low potassium), should avoid taking digoxin unless recommended by a healthcare provider. Pregnant women should consult their doctor before use.
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