Dicyclomine + Mefenamic-acid

Find more information about this combination medication at the webpages for dicyclomine and mefenamic acid

Menorrhagia , Dysmenorrhea ... show more

Drug Status

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Government Approvals

US(FDA)

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WHO Essential Medicine

NO

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Known Teratogen

Possible

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Pharmaceutical Class

Anticholinergic and Nonsteroidal Anti-inflammatory Drug

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Controlled Drug Substance

NO

Summary

  • Dicyclomine is used to relieve muscle spasms in the stomach and intestines, often associated with irritable bowel syndrome, which is a disorder causing abdominal pain and cramping. Mefenamic acid is used to reduce pain and inflammation, particularly for menstrual cramps, which are painful contractions of the uterus. Both medicines aim to alleviate discomfort, though they target different symptoms. Together, they can provide a comprehensive approach to managing pain and muscle spasms.

  • Dicyclomine works by relaxing the muscles in the stomach and intestines, which helps to relieve cramps and spasms associated with irritable bowel syndrome. It does this by blocking the action of acetylcholine, which is a neurotransmitter that causes muscle contractions. Mefenamic acid works by reducing inflammation and pain through its action as a non-steroidal anti-inflammatory drug (NSAID), which inhibits the production of prostaglandins, which are chemicals in the body that cause inflammation and pain.

  • The usual adult dose for dicyclomine is typically 20 mg taken four times a day, but it may be adjusted based on individual needs and response. Mefenamic acid is usually prescribed at a dose of 500 mg initially, followed by 250 mg every 6 hours as needed, not exceeding 7 days of use. Both medicines are taken orally, which means they are swallowed and absorbed through the digestive system. It's important to follow the prescribed dosage to ensure effectiveness and minimize the risk of side effects.

  • Common side effects of dicyclomine include dry mouth, dizziness, blurred vision, and constipation, which are related to its action on the nervous system. Mefenamic acid can cause side effects like stomach upset, nausea, and diarrhea, which are typical for NSAIDs. Both medicines can cause dizziness and should be used with caution when driving or operating machinery. Significant adverse effects may include allergic reactions or severe gastrointestinal issues, such as ulcers or bleeding, particularly with mefenamic acid.

  • Dicyclomine should not be used by individuals with certain conditions like glaucoma, which is increased pressure in the eye, or myasthenia gravis, which is a muscle weakness disorder, due to its anticholinergic effects. Mefenamic acid is contraindicated in people with a history of gastrointestinal bleeding or ulcers, as it can exacerbate these conditions. Both medicines should be used with caution in individuals with kidney or liver issues. It's crucial to follow medical advice and disclose all health conditions to a healthcare provider to avoid serious complications and ensure safe use.

Indications and Purpose

How does combination of Dicyclomine and Mefenamic acid work?

Dicyclomine and Mefenamic acid work together to relieve pain and discomfort, particularly in conditions like menstrual cramps or irritable bowel syndrome. Dicyclomine is an antispasmodic medication, which means it helps to relax the muscles in the stomach and intestines. This relaxation reduces muscle spasms and cramping, providing relief from abdominal pain. Mefenamic acid is a non-steroidal anti-inflammatory drug (NSAID). It works by reducing inflammation and blocking the production of certain natural substances in the body that cause pain and swelling. Together, these medications help to alleviate pain by both relaxing muscle spasms and reducing inflammation.

How effective is combination of Dicyclomine and Mefenamic acid?

The combination of Dicyclomine and Mefenamic acid is often used to relieve symptoms of abdominal pain and cramps, particularly those associated with menstrual periods. Dicyclomine is an antispasmodic medication, which means it helps to relax the muscles in the stomach and intestines, reducing spasms and cramps. Mefenamic acid is a non-steroidal anti-inflammatory drug (NSAID) that helps to reduce inflammation and pain. Together, these medications can be effective in providing relief from pain and discomfort. However, their effectiveness can vary from person to person, and they may not be suitable for everyone. It's important to use them under the guidance of a healthcare professional to ensure they are appropriate for your specific condition and to manage any potential side effects.

Directions for Use

What is the usual dose of combination of Dicyclomine and Mefenamic acid?

The usual dose for a combination of Dicyclomine and Mefenamic acid can vary based on the specific needs of the patient and the guidance of a healthcare provider. However, a common dosage might include Dicyclomine 20 mg and Mefenamic acid 250 mg taken up to four times a day. It's important to follow the dosage instructions provided by a healthcare professional or the information on the medication packaging. Dicyclomine is used to relieve muscle spasms in the stomach and intestines, while Mefenamic acid is a non-steroidal anti-inflammatory drug (NSAID) used to reduce pain and inflammation.

How does one take combination of Dicyclomine and Mefenamic acid?

Dicyclomine is a medication used to relieve muscle spasms in the stomach and intestines, while Mefenamic acid is a non-steroidal anti-inflammatory drug (NSAID) used to relieve pain and inflammation. When taking these medications together, it is important to follow the dosage instructions provided by your healthcare provider or the information on the medication packaging. Typically, Dicyclomine is taken before meals to help reduce stomach spasms, while Mefenamic acid is taken with food or milk to minimize stomach upset. Always use the lowest effective dose for the shortest duration necessary to manage your symptoms. If you have any concerns or experience side effects, consult your healthcare provider for advice. For more detailed information, you can refer to trusted sources like the NHS or DailyMeds.

For how long is combination of Dicyclomine and Mefenamic acid taken?

The combination of Dicyclomine and Mefenamic acid is typically used for short-term relief of symptoms such as abdominal pain and menstrual cramps. According to the NHS and other trusted sources, it is generally recommended to take this combination for the shortest duration necessary to control symptoms, often not exceeding a few days. It's important to follow the specific guidance of a healthcare provider, as they will tailor the duration based on individual needs and response to treatment.

How long does it take for combination of Dicyclomine and Mefenamic acid to work?

Dicyclomine is a medication that helps to relieve muscle spasms in the stomach and intestines, while Mefenamic acid is a non-steroidal anti-inflammatory drug (NSAID) that reduces pain and inflammation. When taken together, these medications can start to relieve symptoms within 1 to 2 hours. However, the exact time can vary depending on individual factors such as the person's metabolism, the severity of symptoms, and whether the medication is taken with food. It's important to follow the dosage instructions provided by a healthcare professional.

Warnings and Precautions

Are there harms and risks from taking combination of Dicyclomine and Mefenamic acid?

Dicyclomine is a medication used to relieve muscle spasms in the stomach and intestines, while Mefenamic acid is a non-steroidal anti-inflammatory drug (NSAID) used to relieve pain and inflammation. Taking these two medications together can increase the risk of certain side effects. 1. **Increased Risk of Gastrointestinal Issues**: Both Dicyclomine and Mefenamic acid can cause gastrointestinal problems. Mefenamic acid, like other NSAIDs, can irritate the stomach lining, potentially leading to ulcers or bleeding. Dicyclomine can slow down the movement of the stomach and intestines, which might exacerbate these issues. 2. **Potential for Increased Side Effects**: Combining these medications may increase the likelihood of experiencing side effects such as dizziness, dry mouth, blurred vision, and constipation, which are common with Dicyclomine. 3. **Consultation with Healthcare Provider**: It is important to consult with a healthcare provider before taking these medications together. They can assess your specific health needs and determine if this combination is safe for you. For more detailed information, you can refer to trusted sources like the [NHS](https://www.nhs.uk/) or [NLM](https://www.nlm.nih.gov/).

Can I take combination of Dicyclomine and Mefenamic acid with other prescription drugs?

When considering taking Dicyclomine and Mefenamic acid with other prescription drugs, it's important to be aware of potential interactions. Dicyclomine is a medication used to relieve muscle spasms in the stomach and intestines, while Mefenamic acid is a non-steroidal anti-inflammatory drug (NSAID) used to relieve pain and inflammation. According to the NHS and NLM, both drugs can interact with other medications. For example, Mefenamic acid can increase the risk of bleeding when taken with other NSAIDs or blood thinners. Dicyclomine can interact with drugs that affect the central nervous system, such as sedatives or antidepressants, potentially increasing side effects like drowsiness. It's crucial to consult with a healthcare provider or pharmacist before combining these drugs with other prescriptions to ensure safety and avoid harmful interactions.

Can I take combination of Dicyclomine and Mefenamic acid if I am pregnant?

It is generally not recommended to take Dicyclomine and Mefenamic acid during pregnancy without consulting a healthcare professional. Dicyclomine is a medication used to relieve muscle spasms in the stomach and intestines, but its safety during pregnancy is not well established. Mefenamic acid is a non-steroidal anti-inflammatory drug (NSAID) used to relieve pain and inflammation. According to the NHS, NSAIDs like Mefenamic acid are usually not recommended during pregnancy, especially in the later stages, as they can affect the baby's circulation and kidney function. Always consult with a healthcare provider before taking any medication during pregnancy to ensure it is safe for you and your baby.

Can I take combination of Dicyclomine and Mefenamic acid while breastfeeding?

When considering the use of Dicyclomine and Mefenamic acid while breastfeeding, it's important to understand the potential effects on both the mother and the baby. Dicyclomine is a medication used to relieve muscle spasms in the stomach and intestines. According to the NHS, it is generally not recommended for breastfeeding mothers because it can pass into breast milk and may affect the baby, potentially causing side effects such as drowsiness or irritability. Mefenamic acid is a non-steroidal anti-inflammatory drug (NSAID) used to relieve pain and inflammation. The NHS advises caution when using Mefenamic acid during breastfeeding, as it can also pass into breast milk. However, if necessary, it may be used for short-term treatment, but always under the guidance of a healthcare professional. Before taking these medications, it is crucial to consult with a healthcare provider to weigh the benefits and risks, and to explore alternative treatments that may be safer during breastfeeding.

Who should avoid taking combination of Dicyclomine and Mefenamic acid?

People who should avoid taking the combination of Dicyclomine and Mefenamic acid include: 1. **Individuals with Allergies:** Those who are allergic to Dicyclomine, Mefenamic acid, or any other ingredients in these medications should not take them. 2. **People with Certain Medical Conditions:** - **Stomach or Intestinal Problems:** Those with a history of stomach ulcers, bleeding, or inflammatory bowel disease should avoid this combination as it can worsen these conditions. - **Heart Conditions:** People with heart disease or high blood pressure should be cautious, as Mefenamic acid can increase the risk of heart problems. - **Kidney or Liver Issues:** Those with kidney or liver problems should avoid these drugs, as they can further impair these organs. 3. **Pregnant or Breastfeeding Women:** These medications can affect the baby, so they should be avoided unless specifically advised by a healthcare provider. 4. **Elderly Individuals:** Older adults may be more sensitive to the side effects of these medications, particularly the risk of stomach bleeding and kidney issues. 5. **Children:** The safety and effectiveness of these drugs in children have not been established, so they should not be used unless prescribed by a doctor. Always consult with a healthcare professional before starting or stopping any medication.