Cefuroxime
Escherichia coli Infections, Bacterial Meningitis ... show more
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Drug Status
Government Approvals
US(FDA), UK(BNF)
WHO Essential Medicine
NO
Known Teratogen
NO
Pharmaceutical Class
Cephalosporin Antibacterial
Controlled Drug Substance
NO
Cefuroxime
Learn more about this medicine -
Click HereSummary
Cefuroxime is an antibiotic used to treat various bacterial infections. These include respiratory tract infections, urinary tract infections, skin infections, and certain sexually transmitted infections like gonorrhea.
Cefuroxime works by stopping the bacteria from forming a protective cell wall. Without this wall, the bacteria become vulnerable and eventually die, helping to clear the infection.
For adults, the typical dosage is 250-500 mg every 12 hours, depending on the infection. For children, doses are based on weight, generally 10-15 mg/kg every 12 hours, up to a maximum of 500 mg twice daily. Cefuroxime is usually taken orally after meals to enhance absorption.
Common side effects of Cefuroxime include diarrhea, nausea, and rash. Serious side effects, such as allergic reactions or severe diarrhea, are rare. If you experience persistent or severe side effects, consult your doctor.
Avoid Cefuroxime if you're allergic to cephalosporins, penicillins, or similar antibiotics. If you have kidney conditions, consult your doctor for dose adjustments. Cefuroxime can pass into breast milk in small amounts and may interact with certain medications, so always inform your doctor about all the medications you're taking.
Indications and Purpose
What is Cefuroxime used for?
Cefuroxime treats infections such as sinusitis, bronchitis, pneumonia, pharyngitis, urinary tract infections, and skin infections. It’s also effective against certain sexually transmitted infections like gonorrhea.
How does Cefuroxime work?
Cefuroxime works by inhibiting bacterial enzymes that build cell walls. Without a protective wall, the bacteria become vulnerable and die.
Is Cefuroxime effective?
Clinical studies confirm Cefuroxime is highly effective in treating bacterial infections, showing significant improvement in symptoms like reduced fever and infection-related discomfort.
How does one know if Cefuroxime is working?
For Cefuroxime, symptom improvement such as better breathing, reduced pain, and no fever indicates that the medication is effective. Lab tests may also show reduced bacterial presence.
Directions for Use
What is the usual dose of Cefuroxime?
For Cefuroxime, adults typically take 250–500 mg every 12 hours, depending on the infection. Children’s doses are calculated based on weight, generally 10–15 mg/kg every 12 hours, with a maximum of 500 mg twice daily. Always follow your doctor's advice.
How do I take Cefuroxime?
Take Cefuroxime tablets after meals to enhance absorption. Shake the oral suspension well before each dose and measure it using the prescribed device. Avoid acidic drinks like orange juice as they may interfere with the medicine.
For how long do I take Cefuroxime?
Cefuroxime is usually taken for 5–14 days, depending on the severity of the infection. Completing the full course ensures the infection is completely treated.
How long does it take for Cefuroxime to start working?
Cefuroxime begins working within 24–48 hours to relieve symptoms. Complete relief may take several days based on the infection's severity.
How should I store Cefuroxime?
Store Cefuroxime tablets at room temperature (20–25°C). Keep the suspension refrigerated and discard unused portions after 10 days.
Warnings and Precautions
Who should avoid taking Cefuroxime?
Avoid Cefuroxime if you are allergic to cephalosporins, penicillins, or similar antibiotics. Patients with kidney conditions should consult a doctor for dose adjustments.
Can I take Cefuroxime with other prescription drugs?
Cefuroxime may interact with antacids, diuretics, or blood-thinning medications like warfarin. Always inform your doctor about all medications you’re taking.
Can I take Cefuroxime with vitamins or supplements?
Take Cefuroxime 2 hours apart from calcium or iron supplements, which can interfere with absorption. Consult your doctor for specific vitamin interactions.
Can Cefuroxime be taken safely while pregnant?
Cefuroxime is considered safe during pregnancy (category B). Animal studies show no harm, but always consult your doctor before using it during pregnancy.
Can Cefuroxime be taken safely while breastfeeding?
Cefuroxime passes into breast milk in small amounts but is generally safe. However, watch for mild diarrhea or other side effects in the baby.
Is Cefuroxime safe for the elderly?
Elderly individuals can safely take Cefuroxime, but dose adjustments may be necessary for those with kidney impairment.
Is it safe to exercise while taking Cefuroxime?
Light to moderate exercise is safe while taking Cefuroxime unless the infection causes fatigue or you experience side effects like dizziness. Listen to your body and avoid overexertion.
Is it safe to drink alcohol while taking Cefuroxime?
Alcohol does not interact with Cefuroxime, but it can worsen side effects like nausea or dizziness. Consume in moderation during treatment.
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