Cabergoline
Parkinson Disease, Adenoma ... show more
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Drug Status
Government Approvals
US(FDA), UK(BNF)
WHO Essential Medicine
YES
Known Teratogen
No
Pharmaceutical Class
Ergot Derivative
Controlled Drug Substance
No
Cabergoline
Summary
Cabergoline is used to treat hyperprolactinemia, a condition characterized by high levels of prolactin hormone. This can lead to symptoms like irregular periods, infertility, and unwanted breast milk production. It may also be used in low doses for Parkinson's disease.
Cabergoline works by mimicking a brain chemical called dopamine. It stimulates dopamine D2 receptors in the hypothalamus, inhibiting the release of prolactin from the anterior pituitary gland. This reduces prolactin levels in the blood, alleviating symptoms caused by its overproduction.
The initial dose for adults is typically 0.25 mg taken orally twice a week. Dose adjustments are made every 4 weeks based on prolactin levels, with a maximum recommended dose of 1 mg twice weekly.
Common side effects include nausea, headache, dizziness, and fatigue. Serious but rare side effects include heart valve disorders, shortness of breath, or fibrosis affecting the lungs or heart.
Cabergoline is contraindicated in individuals with uncontrolled hypertension, heart valve disorders, or a history of fibrotic conditions. It should also be avoided by those allergic to ergot derivatives or those with pregnancy-related hypertension unless benefits outweigh risks.
Indications and Purpose
How does Cabergoline work?
Cabergoline works by mimicking dopamine, a brain chemical that helps regulate prolactin levels. It belongs to a class of drugs called dopamine agonists. By increasing dopamine activity, Cabergoline reduces the production of prolactin, which is a hormone that stimulates milk production. This helps treat conditions like hyperprolactinemia, which is high prolactin levels. Think of it like turning down the volume on a radio to reduce the sound.
Is Cabergoline effective?
Cabergoline is effective in treating conditions like hyperprolactinemia, which is high levels of prolactin in the blood. It works by reducing prolactin levels, helping to restore normal menstrual cycles and fertility in women. Clinical studies support its effectiveness in managing these conditions. If you have concerns about how well Cabergoline is working for you, discuss them with your doctor. They can assess your progress and adjust your treatment if needed.
What is Cabergoline?
Cabergoline is a medication used to treat high levels of prolactin, which is a hormone that stimulates milk production. It belongs to a class of drugs called dopamine agonists, which work by mimicking dopamine, a brain chemical that helps regulate prolactin levels. Cabergoline is primarily used for conditions like hyperprolactinemia, which is high prolactin levels, and can also be used for other conditions as determined by your doctor.
Directions for Use
For how long do I take Cabergoline?
Cabergoline is usually taken long-term for conditions like hyperprolactinemia, which is high levels of prolactin in the blood. The duration of use depends on your response to treatment and your doctor's recommendations. Regular monitoring of prolactin levels will help determine how long you need to take the medication. Always follow your doctor's advice and discuss any concerns about your treatment duration with them.
How do I dispose of Cabergoline?
Dispose of Cabergoline by taking it to a drug take-back program or collection site at a pharmacy or hospital. This ensures safe disposal without harming people or the environment. If a take-back program isn't available, mix the medication with something undesirable like used coffee grounds, seal it in a plastic bag, and throw it away in the trash. Always keep medications out of reach of children and pets.
How do I take Cabergoline?
Take Cabergoline exactly as your doctor prescribes. It's usually taken twice a week. You can take it with or without food. Swallow the tablets whole; do not crush or chew them. If you miss a dose, take it as soon as you remember unless it's almost time for your next dose. In that case, skip the missed dose and continue your regular schedule. Do not take two doses at once. Always follow your doctor's specific instructions regarding your medication.
How long does it take for Cabergoline to start working?
Cabergoline starts working within a few hours of taking it, but it may take several weeks to see the full effects. The time it takes to achieve its full therapeutic effect can vary based on individual factors like your condition and response to treatment. Regular monitoring of prolactin levels will help determine how well the medication is working. Always take Cabergoline as prescribed for the best results.
How should I store Cabergoline?
Store Cabergoline at room temperature, away from moisture and light. Keep it in a tightly closed container to protect it from damage. Avoid storing it in humid places like bathrooms, as moisture can affect the medication's effectiveness. Always keep Cabergoline out of reach of children and pets to prevent accidental ingestion. Check the expiration date regularly and properly dispose of any unused or expired medication.
What is the usual dose of Cabergoline?
The usual starting dose of Cabergoline for adults is 0.25 mg twice a week. Your doctor may adjust the dose based on your response and needs. The maximum recommended dose is 1 mg twice a week. Dose adjustments may be necessary for special populations, such as the elderly. Always follow your doctor's specific dosing instructions for your health needs. Do not change your dose without consulting your healthcare provider.
Warnings and Precautions
Can Cabergoline be taken safely while breastfeeding?
Cabergoline is not recommended while breastfeeding. It may pass into breast milk and affect milk production. Limited information is available on its effects on breastfed infants. If you're taking Cabergoline and wish to breastfeed, discuss alternative treatments with your doctor. They can help you find a safer option that allows you to nurse your baby without compromising your treatment or your child's health.
Can Cabergoline be taken safely while pregnant?
Cabergoline is not recommended during pregnancy unless absolutely necessary. Limited evidence exists on its safety for pregnant women. Animal studies suggest potential risks, but human data is lacking. If you're pregnant or planning to become pregnant, discuss your treatment options with your doctor. They can help determine the safest approach for managing your condition while protecting your health and your baby's well-being.
Can I take Cabergoline with other prescription drugs?
Cabergoline can interact with certain medications, increasing the risk of side effects. Avoid using it with other dopamine agonists, which are drugs that mimic dopamine effects, as this can lead to excessive dopamine activity. Be cautious with blood pressure medications, as Cabergoline can lower blood pressure. Always inform your doctor about all medications you're taking to prevent interactions and ensure safe use of Cabergoline.
Does Cabergoline have adverse effects?
Adverse effects are unwanted reactions to a medication. Cabergoline can cause nausea, dizziness, and headaches, which are common side effects. Serious adverse effects include heart valve problems and fibrosis, which is the thickening of tissue. If you notice any new or worsening symptoms, contact your doctor immediately. They can help determine if these effects are related to Cabergoline and advise on the best course of action.
Does Cabergoline have any safety warnings?
Yes, Cabergoline has important safety warnings. It can cause heart valve problems, which are issues with the heart's ability to pump blood effectively. Regular heart monitoring is recommended. Not following these warnings can lead to serious heart issues. If you experience symptoms like shortness of breath or chest pain, seek medical help immediately. Always discuss any concerns with your doctor and follow their advice closely.
Is Cabergoline addictive?
Cabergoline is not considered addictive or habit-forming. It does not cause physical or psychological dependence. This medication works by affecting dopamine levels in the brain, which helps reduce prolactin levels. If you have concerns about medication dependence, discuss them with your doctor. They can provide reassurance and guidance on how to use Cabergoline safely and effectively for your condition.
Is Cabergoline safe for the elderly?
Elderly individuals may be more vulnerable to the side effects of Cabergoline, such as dizziness and low blood pressure. These effects can increase the risk of falls and other complications. It's important for elderly patients to be closely monitored by their healthcare provider while taking this medication. Dose adjustments may be necessary to ensure safety and effectiveness. Always discuss any concerns with your doctor.
Is it safe to drink alcohol while taking Cabergoline?
It's best to avoid alcohol while taking Cabergoline. Alcohol can increase the risk of side effects like dizziness and low blood pressure. These symptoms can be dangerous and may require medical attention. If you choose to drink occasionally, limit your alcohol intake and watch for warning signs like dizziness or fainting. Discuss alcohol use with your doctor to get personalized advice based on your health situation.
Is it safe to exercise while taking Cabergoline?
You can exercise while taking Cabergoline, but be cautious. This medication can cause dizziness or low blood pressure, which might affect your ability to exercise safely. To exercise safely, stay hydrated and avoid strenuous activities if you feel dizzy. If you notice symptoms like dizziness or unusual fatigue during exercise, slow down or stop and rest. Consult your doctor if you have concerns about exercising while on Cabergoline.
Is it safe to stop Cabergoline?
It's important to consult your doctor before stopping Cabergoline. This medication is often used long-term for conditions like high prolactin levels. Stopping suddenly can cause your symptoms to return or worsen. Your doctor may suggest gradually reducing your dose to prevent any issues. Always follow your healthcare provider's guidance when making changes to your medication regimen to ensure your safety and well-being.
What are the most common side effects of Cabergoline?
Side effects are unwanted reactions to a medication. Common side effects of Cabergoline include nausea, dizziness, and headaches. These occur in a small percentage of people taking the medication. If you experience new symptoms after starting Cabergoline, they might be temporary or unrelated to the medication. Always talk with your doctor before stopping any medication. They can help determine the cause of your symptoms and provide guidance.
Who should avoid taking Cabergoline?
Do not use Cabergoline if you have uncontrolled high blood pressure or a history of heart valve problems. These are absolute contraindications due to severe risks. Use caution if you have liver disease or are pregnant, as these are relative contraindications. Always inform your doctor of your medical history before starting Cabergoline. They can determine if this medication is safe for you and discuss any potential risks.
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