Avanafil
.svg)
Drug Status
Government Approvals
US(FDA), UK(BNF)
WHO Essential Medicine
NO
Known Teratogen
No
Pharmaceutical Class
Phosphodiesterase 5 Inhibitor
Controlled Drug Substance
No
Avanafil
Summary
Avanafil is used to treat erectile dysfunction in adult men. It helps them achieve and maintain an erection sufficient for satisfactory sexual performance.
Avanafil works by inhibiting an enzyme called phosphodiesterase type 5 (PDE5). This leads to increased levels of a substance called cyclic guanosine monophosphate (cGMP) in the body, which relaxes the muscles in the penis and increases blood flow. This helps facilitate an erection during sexual stimulation.
The usual starting dose of Avanafil is 100 mg, taken as needed about 15 minutes before sexual activity. Depending on effectiveness and tolerance, the dose may be increased to 200 mg or decreased to 50 mg. It is not intended for continuous daily use and the maximum recommended frequency is once per day.
Common side effects of Avanafil include headache, flushing, and nasal congestion. Serious adverse effects can include prolonged erection, sudden vision or hearing loss, and severe low blood pressure which require immediate medical attention.
Avanafil should not be used with nitrates or guanylate cyclase stimulators as it can cause severe low blood pressure. It is also contraindicated in patients with severe cardiovascular conditions, recent heart attack or stroke, and those with severe liver or kidney impairment. Drinking alcohol while taking Avanafil can increase the likelihood of experiencing certain side effects.
Indications and Purpose
How does Avanafil work?
Avanafil works by blocking an enzyme called phosphodiesterase type 5, which is found in the blood vessels of the penis. This action increases blood flow to the penis during sexual stimulation, helping to achieve and maintain an erection. Think of it like opening a valve to allow more water to flow through a pipe. This increased blood flow is what helps with erectile function.
Is Avanafil effective?
Yes, Avanafil is effective for treating erectile dysfunction, which is the inability to achieve or maintain an erection. Clinical studies show that Avanafil helps improve erectile function in men with this condition. It works by increasing blood flow to the penis, which helps achieve an erection when sexually stimulated. The effectiveness of Avanafil has been supported by research and is a reliable option for many men.
What is Avanafil?
Avanafil is a medication used to treat erectile dysfunction, which is the inability to achieve or maintain an erection. It belongs to a class of drugs called phosphodiesterase type 5 inhibitors, which work by increasing blood flow to the penis during sexual stimulation. This helps achieve and maintain an erection. Avanafil is taken as needed before sexual activity and is not intended for daily use.
Directions for Use
For how long do I take Avanafil?
Avanafil is taken as needed for erectile dysfunction, which is the inability to achieve or maintain an erection. It is not intended for daily use. You take it about 15 to 30 minutes before sexual activity. The duration of use depends on your individual needs and response to the medication. Always follow your doctor's instructions and discuss any concerns about your treatment plan.
How do I dispose of Avanafil?
To dispose of Avanafil, take it to a drug take-back program or collection site at a pharmacy or hospital. This ensures safe disposal without harming people or the environment. If a take-back program isn't available, mix the medication with something undesirable, like used coffee grounds, seal it in a plastic bag, and throw it away in the trash. Always keep medications out of reach of children.
How do I take Avanafil?
Take Avanafil as directed by your doctor, usually about 15 to 30 minutes before sexual activity. It can be taken with or without food. Do not take more than one dose in a 24-hour period. If you miss a dose, take it as soon as you remember, but do not double up on doses. Avoid alcohol and grapefruit juice, as they can interfere with the effectiveness of the medication. Always follow your doctor's specific instructions.
How long does it take for Avanafil to start working?
Avanafil starts working about 15 to 30 minutes after you take it. The time it takes to achieve its full effect can vary based on individual factors like your overall health and other medications you may be taking. For best results, take Avanafil as directed by your doctor. If you don't notice improvement, talk with your healthcare provider for further guidance.
How should I store Avanafil?
Store Avanafil at room temperature, away from moisture and light. Keep it in its original packaging until you're ready to use it. Do not store it in the bathroom, where humidity can affect the medication. Always keep Avanafil out of reach of children and pets. Check the expiration date regularly and dispose of any unused or expired medication properly.
What is the usual dose of Avanafil?
The usual starting dose of Avanafil for adults is 100 mg taken as needed about 15 to 30 minutes before sexual activity. Depending on effectiveness and tolerance, your doctor may adjust the dose to 50 mg or 200 mg. The maximum recommended dose is 200 mg. Avanafil is not typically used in children or the elderly without specific medical advice. Always follow your doctor's dosing instructions.
Warnings and Precautions
Can Avanafil be taken safely while breastfeeding?
Avanafil is not intended for use in women, including those who are breastfeeding. There is limited information on whether this medication passes into breast milk. Since Avanafil is used to treat erectile dysfunction in men, it is not relevant for breastfeeding women. If you have concerns about medication use while breastfeeding, consult your healthcare provider for guidance.
Can Avanafil be taken safely while pregnant?
Avanafil is not intended for use in women, including during pregnancy. There is limited evidence on the safety of most medications during pregnancy, and Avanafil is specifically used to treat erectile dysfunction in men. If you have concerns about medication use during pregnancy, consult your healthcare provider for advice tailored to your situation.
Can I take Avanafil with other prescription drugs?
Avanafil should not be taken with nitrates, which are medications for chest pain, as this can cause a dangerous drop in blood pressure. It can also interact with certain blood pressure medications and alpha-blockers, which are used for prostate problems. These interactions can increase the risk of side effects. Always inform your doctor about all medications you are taking to avoid potential interactions.
Does Avanafil have adverse effects?
Adverse effects are unwanted reactions to a medication. Common adverse effects of Avanafil include headaches, flushing, and nasal congestion. These occur in more than 10% of users. Serious side effects, like sudden vision loss or an erection lasting more than four hours, require immediate medical attention. If you experience any adverse effects, contact your doctor. They can help determine if Avanafil is the cause and suggest appropriate actions.
Does Avanafil have any safety warnings?
Yes, Avanafil has important safety warnings. It should not be used with nitrates, which are medications for chest pain, as this can cause a dangerous drop in blood pressure. If you experience symptoms like chest pain, dizziness, or nausea during sex, seek immediate medical help. Not adhering to these warnings can lead to serious health risks. Always discuss your medical history with your doctor before using Avanafil.
Is Avanafil addictive?
Avanafil is not addictive or habit-forming. It does not cause dependency or withdrawal symptoms. Avanafil works by increasing blood flow to the penis to help achieve an erection, and it does not affect brain chemistry in a way that leads to addiction. You won't experience cravings for this medication. If you have concerns about medication dependence, rest assured that Avanafil does not carry this risk.
Is Avanafil safe for the elderly?
Avanafil can be used by the elderly, but they may be more sensitive to its effects. Older adults are more vulnerable to side effects like dizziness or low blood pressure. It's important for elderly users to start with a lower dose and be closely monitored by their doctor. Always discuss your health conditions and medications with your healthcare provider to ensure Avanafil is safe for you.
Is it safe to drink alcohol while taking Avanafil?
It's best to limit alcohol consumption while taking Avanafil. Alcohol can increase the risk of side effects like dizziness and can lower blood pressure, which may interfere with the effectiveness of the medication. If you choose to drink, do so in moderation and be aware of how your body responds. Talk with your doctor about alcohol use while taking Avanafil for personalized advice.
Is it safe to exercise while taking Avanafil?
Yes, it's generally safe to exercise while taking Avanafil. However, be mindful of how your body feels during physical activity. Avanafil can cause dizziness or lightheadedness, especially if you have low blood pressure. Stay hydrated and avoid strenuous activities if you feel unwell. If you experience any unusual symptoms during exercise, stop and rest. Consult your doctor if you have concerns about exercising while on this medication.
Is it safe to stop Avanafil?
Yes, it is safe to stop taking Avanafil. This medication is used as needed for erectile dysfunction, so you can stop without withdrawal symptoms. However, stopping may result in the return of erectile dysfunction symptoms. Always discuss with your doctor before making changes to your medication routine to ensure it aligns with your health needs and treatment goals.
What are the most common side effects of Avanafil?
Side effects are unwanted reactions to a medication. Common side effects of Avanafil include headaches, flushing, and nasal congestion, affecting more than 10% of users. These side effects are usually mild and temporary. If you experience new symptoms after starting Avanafil, they might be unrelated to the medication. Always talk with your doctor before stopping any medication to ensure your treatment remains effective.
Who should avoid taking Avanafil?
Avanafil should not be used if you are taking nitrates, which are medications for chest pain, as this can cause a dangerous drop in blood pressure. It's also contraindicated in people with severe liver or kidney problems. Caution is needed if you have heart disease or a history of stroke. Always consult your doctor to ensure Avanafil is safe for you, considering your medical history.
Forms / Brands
