Aripiprazole
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Drug Status
Government Approvals
US(FDA), UK(BNF)
WHO Essential Medicine
NO
Known Teratogen
No
Pharmaceutical Class
Atypical Antipsychotic
Controlled Drug Substance
No
aripiprazole
Summary
Aripiprazole is used to treat schizophrenia, which is a mental disorder causing hallucinations and delusions, and bipolar disorder, which involves extreme mood swings. It can also be an add-on treatment for depression, which is a condition causing persistent sadness and loss of interest.
Aripiprazole works by balancing chemicals in the brain, specifically dopamine and serotonin, which are neurotransmitters involved in mood and behavior. This helps reduce symptoms like hallucinations, mood swings, and depression, making it easier for individuals to manage their conditions.
Aripiprazole is typically taken as a tablet once daily, either in the morning or evening, with or without food. The usual starting dose for adults is 10 to 15 mg per day, with a maximum dose of 30 mg. Dosage may vary for children and the elderly.
Common side effects of Aripiprazole include nausea, which is a feeling of sickness with an inclination to vomit, vomiting, dizziness, which is a sensation of spinning or losing balance, and insomnia, which is trouble sleeping. These effects are usually mild and vary from person to person.
Aripiprazole may increase the risk of suicidal thoughts, especially in young people. It can cause neuroleptic malignant syndrome, which is a severe reaction with symptoms like high fever and muscle stiffness. Avoid if allergic to it, and consult a doctor if you have seizures or heart problems.
Indications and Purpose
How does Aripiprazole work?
Aripiprazole works by balancing certain chemicals in the brain, which helps improve symptoms of mental health conditions. It acts on dopamine and serotonin receptors, which are involved in mood and behavior. Think of it like adjusting the volume on a radio to get a clearer sound. This helps reduce symptoms like hallucinations and mood swings.
Is Aripiprazole effective?
Yes, Aripiprazole is effective for treating conditions like schizophrenia and bipolar disorder. It works by balancing certain chemicals in the brain, which helps improve symptoms. Clinical studies show that Aripiprazole can reduce symptoms like hallucinations and mood swings. It is also used as an add-on treatment for depression. Always follow your doctor's instructions to achieve the best results.
What is Aripiprazole?
Aripiprazole is an antipsychotic medication used to treat conditions like schizophrenia and bipolar disorder. It works by balancing certain chemicals in the brain, which helps improve symptoms like hallucinations and mood swings. Aripiprazole can also be used as an add-on treatment for depression. It is usually taken long-term to manage these conditions.
Directions for Use
For how long do I take Aripiprazole?
Aripiprazole is usually taken long-term for managing chronic conditions like schizophrenia or bipolar disorder. The duration depends on your response, side effects, and overall health. Your doctor will guide you on how long to continue the medication. Always talk with your doctor before changing or stopping your treatment.
How do I dispose of Aripiprazole?
Dispose of Aripiprazole by taking it to a drug take-back program or collection site at a pharmacy or hospital. If that's not possible, mix the medication with something undesirable like used coffee grounds, seal it in a plastic bag, and throw it away in the trash. This helps prevent harm to people and the environment.
How do I take Aripiprazole?
Take Aripiprazole exactly as your doctor prescribes. It's usually taken once daily, either in the morning or evening, with or without food. Swallow the tablet whole; do not crush or chew it. If you miss a dose, take it as soon as you remember unless it's close to your next dose. In that case, skip the missed dose. Do not double up on doses. Avoid alcohol while taking Aripiprazole, as it can increase side effects. Always follow your doctor's specific instructions.
How long does it take for Aripiprazole to start working?
Aripiprazole may start working within a few days, but it can take several weeks to achieve its full effect. The time it takes to work can vary based on individual factors like age and overall health. It's important to take it exactly as prescribed and have regular check-ups with your doctor to monitor progress.
How should I store Aripiprazole?
Store Aripiprazole at room temperature, away from moisture and light. Keep it in a tightly closed container. Do not store it in humid places like bathrooms. Always keep it out of reach of children. Check the expiration date regularly and dispose of any unused or expired medication properly.
What is the usual dose of Aripiprazole?
The usual starting dose of Aripiprazole for adults is 10 to 15 mg once daily. Your doctor may adjust the dose based on your response and needs. The maximum recommended dose is 30 mg per day. For children and the elderly, dose adjustments may be necessary, and they should be closely monitored. Always follow your doctor's specific dosing instructions for your health needs.
Warnings and Precautions
Can Aripiprazole be taken safely while breastfeeding?
The safety of Aripiprazole while breastfeeding is not well-established. It's unclear if the medication passes into breast milk. Discuss with your doctor if you're breastfeeding or planning to breastfeed. They can help determine the best treatment options for you and your baby, considering potential risks and benefits.
Can Aripiprazole be taken safely while pregnant?
The safety of Aripiprazole during pregnancy is not well-established. Limited evidence suggests potential risks, so it's important to discuss with your doctor if you're pregnant or planning to become pregnant. They can help create a treatment plan that considers the benefits and risks to both you and your baby.
Can I take Aripiprazole with other prescription drugs?
Aripiprazole can interact with other medications, increasing the risk of side effects or reducing effectiveness. For example, combining it with other central nervous system depressants can increase drowsiness. Always inform your doctor about all medications you take to avoid interactions. They can help manage your treatment safely.
Does Aripiprazole have adverse effects?
Yes, Aripiprazole can have adverse effects, which are unwanted reactions to a medication. Common adverse effects include nausea, vomiting, and dizziness. Serious side effects can include seizures and changes in mood or behavior. If you notice any new or worsening symptoms, contact your doctor immediately. They can help determine if these symptoms are related to Aripiprazole and suggest appropriate actions.
Does Aripiprazole have any safety warnings?
Yes, Aripiprazole has important safety warnings. It may increase the risk of suicidal thoughts, especially in young people. It can also cause neuroleptic malignant syndrome, which is a severe reaction with symptoms like high fever and muscle stiffness. Not following safety warnings can lead to serious health issues. Always discuss any concerns with your doctor and follow their guidance closely.
Is Aripiprazole addictive?
No, Aripiprazole is not considered addictive or habit-forming. It does not cause dependency or withdrawal symptoms when you stop taking it. Aripiprazole works by affecting certain chemicals in the brain but does not lead to addiction. You won't experience cravings or feel compelled to take more than prescribed. If you have concerns about medication dependence, discuss them with your doctor.
Is Aripiprazole safe for the elderly?
Aripiprazole can be used by the elderly, but they may be more vulnerable to side effects like dizziness and low blood pressure. These effects can increase the risk of falls. Close monitoring by a healthcare provider is important. The doctor may adjust the dose to minimize risks and ensure safety.
Is it safe to drink alcohol while taking Aripiprazole?
It's best to avoid alcohol while taking Aripiprazole. Alcohol can increase the risk of side effects like dizziness and drowsiness. It may also interfere with the effectiveness of the medication. If you choose to drink occasionally, limit your alcohol intake and watch for any warning signs. Discuss alcohol use with your doctor for personalized advice.
Is it safe to exercise while taking Aripiprazole?
Yes, you can exercise while taking Aripiprazole, but be mindful of how your body feels. The medication can cause dizziness or drowsiness, which might affect your exercise capacity. Stay hydrated and avoid strenuous activities if you feel unwell. If you experience unusual symptoms during exercise, slow down or stop and rest. Consult your doctor if you have concerns.
Is it safe to stop Aripiprazole?
No, it's not safe to stop Aripiprazole suddenly without consulting your doctor. Stopping it abruptly can cause your symptoms to return or worsen. There are no specific withdrawal symptoms, but your doctor may suggest gradually reducing your dose to avoid any potential issues. Always talk with your doctor before making any changes to your medication.
What are the most common side effects of Aripiprazole?
Common side effects of Aripiprazole include nausea, vomiting, dizziness, and insomnia, which is trouble sleeping. These side effects vary from person to person and are usually mild. If you experience new symptoms after starting Aripiprazole, they might be temporary or unrelated to the medication. Always talk with your doctor before stopping any medication.
Who should avoid taking Aripiprazole?
Aripiprazole should not be used if you are allergic to it or its ingredients. Serious allergic reactions require immediate medical help. Caution is needed for people with a history of seizures or heart problems. Always consult your doctor about any health concerns before starting Aripiprazole. They can help determine if the benefits outweigh the risks for your specific situation.
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