Alfuzosin
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Drug Status
Government Approvals
US(FDA), UK(BNF)
WHO Essential Medicine
NO
Known Teratogen
NO
Pharmaceutical Class
Alpha-Adrenergic Blocker
Controlled Drug Substance
NO
Alfuzosin
Summary
Alfuzosin is a medication used to treat the symptoms of an enlarged prostate in adult men. It is not intended for use by women or children.
Alfuzosin works by relaxing the muscles around the bladder and prostate, which helps urine flow more easily. It does not typically affect weight, appetite, or eating behaviors.
Alfuzosin is typically administered as extended-release tablets taken with food and the same meal each day. The tablets should not be crushed or chewed as they are designed to release the medication slowly over time.
Common side effects of Alfuzosin include dizziness, headaches, and fatigue. Other side effects include upper respiratory tract infection, abdominal pain, and nausea. Serious side effects include a sudden drop in blood pressure and a painful, long-lasting erection known as priapism.
Alfuzosin can lower blood pressure, especially when first taken, which could cause dizziness or fainting. It should not be taken if you have liver problems, are taking certain antifungal or anti-HIV medicines, or are allergic to Alfuzosin. It is important to avoid driving or operating machinery until you know how Alfuzosin affects you.
Indications and Purpose
How does Alfuzosin work?
Alfuzosin is an alpha blocker that selectively targets alpha-1 adrenergic receptors in the prostate and bladder. By blocking these receptors, it relaxes the smooth muscles in these areas, improving urine flow and reducing symptoms of benign prostatic hyperplasia (BPH).
How does one know if Alfuzosin is working?
The benefit of Alfuzosin is evaluated by monitoring the improvement in urinary symptoms associated with benign prostatic hyperplasia (BPH). Regular follow-up appointments with your doctor will help assess the effectiveness of the treatment and make any necessary adjustments.
Is Alfuzosin effective?
Clinical trials have shown that Alfuzosin significantly improves urinary flow rates and reduces symptoms of benign prostatic hyperplasia (BPH). Patients reported a reduction in symptom severity and an increase in peak urinary flow rate, demonstrating the medication's effectiveness.
What is Alfuzosin?
Alfuzosin is used to treat symptoms of an enlarged prostate, such as difficulty urinating. It belongs to a class of medications called alpha blockers, which work by relaxing the muscles in the prostate and bladder, allowing urine to flow more easily.
What is Alfuzosin used for?
Alfuzosin is indicated for the treatment of symptoms associated with benign prostatic hyperplasia (BPH) in men. It helps alleviate urinary difficulties such as hesitation, dribbling, weak stream, and incomplete bladder emptying.
Directions for Use
For how long do I take Alfuzosin?
Alfuzosin is typically used as a long-term treatment for symptoms of an enlarged prostate. It is important to continue taking it even if you feel well, as it controls symptoms but does not cure the condition.
How do I dispose of Alfuzosin?
If you can, bring unused medicines to a drug take-back program or collection site at a pharmacy or hospital. They will dispose of this medicine properly so they don't harm people or the environment. If you can't find a take-back program, you can throw most medicines in the trash at home. But first, take them out of their original containers, mix them with something undesirable like used coffee grounds, seal the mixture in a plastic bag and throw it away.
How do I take Alfuzosin?
Take Alfuzosin as an extended-release tablet once daily, immediately after a meal. Do not take it on an empty stomach. Swallow the tablet whole without crushing or chewing. Discuss with your doctor about consuming grapefruit or grapefruit juice while on this medication.
How long does it take for Alfuzosin to start working?
Alfuzosin may start to improve symptoms within a few days, but it can take up to a few weeks to experience the full benefits. Continue taking the medication as prescribed, even if you feel well.
How should I store Alfuzosin?
Store Alfuzosin in its original container, tightly closed, at room temperature away from light, excess heat, and moisture. Keep it out of reach of children. Do not store it in the bathroom. Dispose of unneeded medication through a take-back program.
What is the usual dose of Alfuzosin?
The usual daily dose for adults is one 10 mg extended-release tablet taken once daily. Alfuzosin is not indicated for use in children.
Warnings and Precautions
Can Alfuzosin be taken safely while breastfeeding?
Alfuzosin is not indicated for use in women, including those who are breastfeeding. There is no data on its presence in human milk or its effects on the breastfed child. Consult a healthcare provider for personalized advice.
Can Alfuzosin be taken safely while pregnant?
Alfuzosin is not indicated for use in women, especially during pregnancy. There is no adequate data on the developmental risk associated with its use in pregnant women. Consult a healthcare provider for personalized advice.
Can I take Alfuzosin with other prescription drugs?
Alfuzosin should not be taken with potent CYP3A4 inhibitors like ketoconazole, itraconazole, or ritonavir, as these can increase Alfuzosin blood levels. Caution is advised when used with other alpha-blockers, antihypertensive medications, and PDE5 inhibitors due to the risk of hypotension.
Can I take Alfuzosin with vitamins or supplements?
There are no well-documented interactions between Alfuzosin and vitamins or supplements. However, it's always important to inform your healthcare provider about all medications and supplements you are taking. This helps them monitor for any potential interactions and ensure your treatment is safe and effective.
Does Alfuzosin have adverse effects?
Adverse effects are unwanted or harmful effects caused by a medicine. For Alfuzosin, common adverse effects include dizziness, headache, and tiredness. Serious but rare effects might include chest pain or a severe drop in blood pressure, which need immediate medical attention. Always report new symptoms to your healthcare provider and consult them before stopping the medicine.
Does Alfuzosin have any safety warnings?
Alfuzosin has safety warnings related to its effect on blood pressure. It can cause a sudden drop in blood pressure, especially when standing up, leading to dizziness or fainting. Be cautious when getting up from sitting or lying down. If you experience severe dizziness, chest pain, or a fast heartbeat, seek medical attention immediately. Always follow your doctor's instructions and report any unusual symptoms.
Is Alfuzosin addictive?
Alfuzosin is not known to be addictive. It does not have habit-forming potential, so there is no risk of physical or psychological dependence. You can take it as prescribed by your doctor without worrying about addiction. Always follow your healthcare provider's instructions and discuss any concerns you may have.
Is Alfuzosin safe for the elderly?
Elderly patients may be more sensitive to the effects of Alfuzosin, particularly the risk of dizziness and fainting. It is important for elderly patients to be cautious when standing up quickly and to avoid activities that require full alertness until they know how the medication affects them.
Is it safe to drink alcohol while taking Alfuzosin?
Most people tolerate Alfuzosin well, and occasional alcoholic drinks should not affect the way this medicine works. However, alcohol can increase the risk of dizziness or fainting, especially when standing up. It's best to limit alcohol consumption and be cautious when drinking. If you experience any unusual symptoms, consult your healthcare provider.
Is it safe to exercise while taking Alfuzosin?
Alfuzosin may cause dizziness or lightheadedness, especially when you first start taking it. This could potentially affect your ability to exercise safely. If you experience these symptoms, it is advisable to avoid strenuous activities until you know how the medication affects you.
Is it safe to stop Alfuzosin?
Alfuzosin is typically used for managing symptoms of an enlarged prostate, a chronic condition. Stopping it suddenly might cause symptoms like difficulty urinating to return. There are no known withdrawal symptoms, but it's crucial to consult your doctor before stopping. They can guide you on how to safely discontinue or adjust your medication.
What are the most common side effects of Alfuzosin?
A side effect is an unwanted reaction to a medicine. Common side effects of Alfuzosin include dizziness, headache, tiredness, and nausea. These effects are usually mild and may go away as your body adjusts. It's important to remember that new symptoms might not be related to the medicine. Always talk to your healthcare provider before stopping any medication.
Who should avoid taking Alfuzosin?
Alfuzosin should not be used in patients with moderate or severe liver impairment or those taking potent CYP3A4 inhibitors. It may cause dizziness and fainting, especially when standing up quickly. Patients should be cautious when driving or operating machinery. Women, especially those who are pregnant or breastfeeding, should not take Alfuzosin.
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