Acenocoumarol

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Drug Status

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Government Approvals

UK(BNF)

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WHO Essential Medicine

NO

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Known Teratogen

Definite

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Pharmaceutical Class

Vitamin K Antagonist

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Controlled Drug Substance

NO

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Drug Ingredient

Acenocoumarol

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Summary

  • Acenocoumarol is a blood thinner used to prevent blood clots that can cause serious problems like strokes, heart attacks, and blockages in the lungs. Doctors prescribe it for people at risk of these clots, such as those with irregular heartbeats, a history of heart attacks, artificial heart valves or certain blood disorders.

  • Acenocoumarol works by blocking a vitamin K, which is needed to make proteins that help blood clot. This affects how the body absorbs the vitamin and changes how the body processes it. Most of the drug leaves the body through urine and stool.

  • For adults, doctors usually start with a daily dose between 2 and 4 milligrams of Acenocoumarol. The amount needed to keep blood thin can vary, so the daily dose might change to be between 1 and 8 milligrams.

  • Acenocoumarol can cause serious bleeding in many parts of the body like the stomach, brain, or kidneys. This bleeding can be life-threatening. Other side effects are less serious, such as skin rashes, feeling sick to your stomach, and hair loss.

  • Acenocoumarol is very dangerous to take while pregnant as it can harm the unborn baby. Serious bleeding is a risk, even death. Many other medicines can affect how well Acenocoumarol works, so it's vital to have regular blood tests, especially if you start or stop other medications.

Indications and Purpose

Directions for Use

Warnings and Precautions