Aceclofenac + Paracetamol

Find more information about this combination medication at the webpages for Aceclofenac and Paracetamol

Advisory

  • इस दवा में 2 दवाओं Aceclofenac और Paracetamol का संयोजन है।
  • Aceclofenac और Paracetamol दोनों का उपयोग एक ही बीमारी या लक्षण के इलाज के लिए किया जाता है, लेकिन शरीर में अलग-अलग तरीके से काम करते हैं।
  • अधिकांश डॉक्टर संयोजन रूप का उपयोग करने से पहले यह सुनिश्चित करने की सलाह देंगे कि प्रत्येक व्यक्तिगत दवा सुरक्षित और प्रभावी है।

Drug Status

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Government Approvals

None

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WHO Essential Medicine

NO

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Known Teratogen

No

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Pharmaceutical Class

None

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Controlled Drug Substance

NO

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Drug Ingredient

Aceclofenac + Paracetamol

Summary

  • Aceclofenac is primarily used to treat inflammatory conditions such as arthritis, which involves joint inflammation causing pain and stiffness. It is effective in reducing inflammation and pain associated with osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis, which is a type of arthritis affecting the spine.

  • Paracetamol is commonly used to relieve mild to moderate pain and reduce fever. It is effective for general pain relief, such as headaches, muscle aches, and toothaches, and is often used to manage fever associated with colds and flu.

  • Aceclofenac works by blocking the production of prostaglandins, which are chemicals in the body that cause inflammation and pain. As a non-steroidal anti-inflammatory drug (NSAID), it reduces inflammation and alleviates pain by inhibiting the enzymes responsible for prostaglandin synthesis.

  • Paracetamol works by reducing the production of prostaglandins in the brain, which are chemicals that signal pain and regulate body temperature. It acts as an analgesic, which means it relieves pain, and an antipyretic, which means it reduces fever.

  • The usual adult dose of Aceclofenac is 100 mg taken twice a day. It is typically administered orally in tablet form. It is recommended to take Aceclofenac with food to minimize the risk of stomach upset.

  • The usual adult dose of Paracetamol is 500 mg to 1000 mg every 4 to 6 hours, not exceeding 4000 mg in a day. It is typically taken orally in tablet or liquid form and can be taken with or without food.

  • Common side effects of Aceclofenac include stomach pain, nausea, and diarrhea. More serious adverse effects can include gastrointestinal bleeding, which refers to bleeding in the stomach or intestines, and kidney problems.

  • Paracetamol is generally well-tolerated, but in rare cases, it can cause liver damage, especially if taken in high doses. It is important to adhere to the recommended dosage to avoid potential liver-related side effects.

  • Aceclofenac should be avoided by individuals with a history of stomach ulcers or bleeding, as well as those taking blood thinners. It can also affect kidney function, so caution is advised for people with kidney issues. Pregnant or breastfeeding women should consult a doctor before use.

  • Paracetamol should be used with caution in individuals with liver problems or those who consume alcohol regularly, as it can increase the risk of liver damage. It is important to avoid exceeding the recommended dose and to consult a healthcare provider if taking other medications.

Indications and Purpose

How does combination of Aceclofenac and Paracetamol work?

Aceclofenac and Paracetamol are both used to relieve pain and reduce inflammation, which refers to the body's response to injury or infection that often causes redness, swelling, and pain. Aceclofenac is a non-steroidal anti-inflammatory drug, which means it works by blocking the production of certain chemicals in the body called prostaglandins that cause inflammation and pain. It is often used for conditions like arthritis, which is a disease causing painful inflammation and stiffness of the joints. Paracetamol, on the other hand, is an analgesic, which means it relieves pain, and an antipyretic, which means it reduces fever. It works by affecting the chemicals in the brain that send pain signals and control body temperature. Both medicines share the common attribute of pain relief, but they work in different ways and are often used together to enhance their effects.

How effective is combination of Aceclofenac and Paracetamol?

Aceclofenac and Paracetamol are both effective in relieving pain and reducing inflammation. Aceclofenac is a non-steroidal anti-inflammatory drug, which means it works by reducing hormones that cause inflammation and pain in the body. It is particularly effective for conditions like arthritis. Paracetamol, also known as acetaminophen, is an analgesic, which means it relieves pain, and an antipyretic, which means it reduces fever. It is often used for mild to moderate pain and fever. Both Aceclofenac and Paracetamol share the common attribute of being pain relievers. They are often combined to enhance pain relief, as they work through different mechanisms. While Aceclofenac targets inflammation, Paracetamol is gentler on the stomach and can be used by people who cannot tolerate NSAIDs. Together, they provide a balanced approach to managing pain and inflammation.

Directions for Use

What is the usual dose of combination of Aceclofenac and Paracetamol?

The usual adult daily dose for Aceclofenac, which is a non-steroidal anti-inflammatory drug used to relieve pain and inflammation, is typically 100 mg taken twice a day. Paracetamol, which is a pain reliever and fever reducer, is usually taken in doses of 500 mg to 1000 mg every 4 to 6 hours, not exceeding 4000 mg in a day. Aceclofenac is particularly effective for conditions like arthritis, which refers to inflammation of the joints, while Paracetamol is often used for general pain relief and reducing fever. Both medicines share the common attribute of providing pain relief, but they work in different ways. Aceclofenac reduces inflammation, which is the body's response to injury or infection, while Paracetamol works by blocking pain signals in the brain. It's important to follow dosing instructions to avoid side effects.

How does one take combination of Aceclofenac and Paracetamol?

Aceclofenac, which is a non-steroidal anti-inflammatory drug (NSAID) used to relieve pain and inflammation, is best taken with food to reduce the risk of stomach upset. Paracetamol, which is a pain reliever and fever reducer, can be taken with or without food. However, taking it with food may help if it causes stomach discomfort. Both medicines are used to manage pain, but they work in different ways. Aceclofenac reduces inflammation, while Paracetamol primarily reduces pain and fever. There are no specific food restrictions for either medicine, but it's important to avoid alcohol while taking them, as it can increase the risk of liver damage, especially with Paracetamol. Always follow the dosage instructions provided by your healthcare provider and consult them if you have any concerns or experience any side effects.

For how long is combination of Aceclofenac and Paracetamol taken?

Aceclofenac, which is a non-steroidal anti-inflammatory drug (NSAID) used to relieve pain and inflammation, is typically used for short-term treatment. It is often prescribed for conditions like arthritis, which refers to joint inflammation, and is usually taken for a few days to a couple of weeks, depending on the condition and doctor's advice. Paracetamol, which is a pain reliever and fever reducer, is also used for short-term relief of mild to moderate pain and fever. It can be taken for a few days, but prolonged use should be under medical supervision. Both medicines are used to manage pain, but Aceclofenac also reduces inflammation, which Paracetamol does not. They are both generally well-tolerated when used as directed, but long-term use should be monitored by a healthcare professional to avoid potential side effects.

How long does it take for combination of Aceclofenac and Paracetamol to work?

The time it takes for a combination medicine to start working depends on the individual medicines involved. For example, if the combination includes ibuprofen, which is a pain reliever and anti-inflammatory drug, it typically starts working within 20 to 30 minutes. On the other hand, if the combination includes acetaminophen, which is another pain reliever, it usually begins to work within 30 to 60 minutes. Both medicines are used to relieve pain, but ibuprofen also reduces inflammation, which refers to swelling and redness in the body. When combined, these medicines can provide faster and more comprehensive pain relief. However, the exact time for the combination to start working can vary based on the specific formulation and the individual's response to the medication.

Warnings and Precautions

Are there harms and risks from taking combination of Aceclofenac and Paracetamol?

Aceclofenac, which is a non-steroidal anti-inflammatory drug (NSAID), commonly causes side effects like stomach pain, nausea, and diarrhea. Significant adverse effects can include gastrointestinal bleeding, which refers to bleeding in the stomach or intestines, and kidney problems. Paracetamol, which is a pain reliever and fever reducer, usually has fewer side effects, but in rare cases, it can cause liver damage, especially if taken in high doses. Both Aceclofenac and Paracetamol are used to relieve pain and reduce fever. However, Aceclofenac is more likely to cause stomach-related issues, while Paracetamol is generally safer for the stomach but can affect the liver if overused. It's important to use both medications as directed to minimize risks. They share the common attribute of providing pain relief, but they differ in their side effect profiles and potential adverse effects.

Can I take combination of Aceclofenac and Paracetamol with other prescription drugs?

Aceclofenac, which is a non-steroidal anti-inflammatory drug (NSAID), and Paracetamol, which is a pain reliever and fever reducer, both have interactions with other medications. Aceclofenac can interact with blood thinners, which are medications that prevent blood clots, increasing the risk of bleeding. It can also interact with other NSAIDs, increasing the risk of stomach ulcers. Paracetamol can interact with alcohol, which can increase the risk of liver damage. Both drugs can interact with medications that affect the liver, as they are processed by the liver. It's important to avoid taking more than the recommended dose of either medication to prevent liver damage. Always consult a healthcare provider before combining these medications with others to ensure safety.

Can I take combination of Aceclofenac and Paracetamol if I am pregnant?

Aceclofenac is a non-steroidal anti-inflammatory drug, which is a type of medication used to reduce inflammation and pain. During pregnancy, it is generally not recommended because it may affect the development of the baby, especially in the later stages. Paracetamol, which is also known as acetaminophen, is a pain reliever and fever reducer. It is considered safer during pregnancy and is often recommended for managing mild to moderate pain or fever. Both Aceclofenac and Paracetamol are used to relieve pain, but they work in different ways. Aceclofenac reduces inflammation, while Paracetamol does not. Paracetamol is usually preferred during pregnancy due to its safety profile. However, it is important for pregnant women to consult their healthcare provider before taking any medication to ensure it is safe for them and their baby.

Can I take combination of Aceclofenac and Paracetamol while breastfeeding?

Aceclofenac, which is a non-steroidal anti-inflammatory drug (NSAID), is generally not recommended during breastfeeding due to limited data on its safety. It may pass into breast milk and could potentially affect the baby. Paracetamol, which is a pain reliever and fever reducer, is considered safe during breastfeeding. It is one of the most commonly used medications for pain and fever in nursing mothers, as only small amounts pass into breast milk and it is unlikely to harm the baby. Both Aceclofenac and Paracetamol are used to relieve pain and reduce inflammation, but they work in different ways. Aceclofenac is more potent in reducing inflammation, while Paracetamol is preferred for its safety profile during breastfeeding. When considering medication during lactation, Paracetamol is usually the safer choice, while Aceclofenac should be used with caution and under medical advice.

Who should avoid taking combination of Aceclofenac and Paracetamol?

Aceclofenac, which is a non-steroidal anti-inflammatory drug (NSAID), can cause stomach issues like ulcers or bleeding. It should be avoided by people with a history of stomach problems or those taking blood thinners. It can also affect kidney function, so people with kidney issues should be cautious. Paracetamol, which is a pain reliever and fever reducer, can cause liver damage if taken in high doses or with alcohol. People with liver problems should avoid it. Both Aceclofenac and Paracetamol can cause allergic reactions, so anyone with a known allergy to these drugs should not take them. They should not be used together with other NSAIDs or pain relievers without consulting a doctor. Pregnant or breastfeeding women should seek medical advice before using these medications. Always follow the prescribed dosage to avoid potential side effects.