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Tribet 2 mg/500 mg/7.5 mg Tablet SR 15s

Introduction

This Medicine is commonly prescribed medications used in the management of type 2 diabetes mellitus It is a combination of three medications Glimepiride, Metformin and Pioglitazone

Each of these drugs contributes to diabetes control in different ways

Glimepiride: This belongs to the sulfonylurea class and stimulates the release of insulin from the pancreas It helps lower blood sugar levels by increasing the amount of insulin produced by the body

Metformin: This is a biguanide that improves insulin sensitivity, reducing the amount of glucose produced by the liver and enhancing the body's response to insulin It also helps lower blood sugar levels

Pioglitazone: A thiazolidinedione, it works by improving insulin sensitivity in the body's cells, allowing them to better respond to insulin This results in lower blood sugar levels

Follow the prescribed dosage provided by your healthcare provider This medication often comes in a fixeddose combination, and the number of tablets to be taken may vary

Tribet 2 mg/500 mg/7.5 mg Tablet SR 15s is usually taken with meals to help reduce the risk of stomach upset

Some common side effects with this medication combination The blood sugarlowering effect may lead to hypoglycemia, manifesting as shakiness, dizziness, sweating, and confusion Gastrointestinal issues such as nausea, diarrhea, or abdominal discomfort may occur Additionally, some individuals might experience fluctuations in weight

Due to the potential impact on the kidneys, those taking Metformin may undergo regular kidney function tests Similarly, periodic liver function tests may be recommended because of potential effects on the liver

If a dose is inadvertently missed, prompt action is necessary Take the missed dose as soon as you remember, unless the next scheduled dose is imminent In such cases, it's advisable to skip the missed dose to avoid doubling up

How it works

Glimepiride, a sulfonylurea, stimulates insulin release from the pancreas, aiding in blood glucose reduction. Metformin, a biguanide, targets hepatic glucose production and enhances peripheral insulin sensitivity. Pioglitazone, a thiazolidinedione, improves insulin sensitivity in adipose tissue and skeletal muscle. Together, these medications act synergistically to regulate insulin secretion, reduce hepatic glucose output, and enhance peripheral glucose utilization. This combination offers an effective strategy for managing diabetes by addressing multiple facets of glucose homeostasis.

How to take

["Follow your doctor's guidance for this medicine, taking it in the prescribed dose and duration","You can take this medicine with or without food, but maintaining a consistent time daily is recommended for better results","Swallow the drug whole; avoid chewing, crushing, or breaking it"]

Adverse drug effect

Tribet 2 mg/500 mg/7.5 mg Tablet SR may cause side effects like infections, vision problems, weight gain, numbness, nausea, diarrhea, stomach pain, headache, or low blood sugar. Monitor for signs of liver problems, heart failure, or bladder cancer. Consult your doctor if side effects persist or worsen, and seek immediate medical attention for serious allergic reactions.

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